Yazar "Kilic, Selcuk" seçeneğine göre listele

Listeleniyor 1 - 3 / 3
  • Küçük Resim
    Öğe
    Investigation of Antibodies Against Listeria monocytogenes in Ram and Ewes in Ankara Province
    (Kafkas Univ, Veteriner Fakultesi Dergisi, 2009) Gazyagci, Serkal; Yildirim, Murat; Babur, Cahit; Kilic, Selcuk
    This study was conducted on determination seroprevalance of listeriosis in sacrifial ewes and rams in Ankara. Antibody titers were detected against Listeria monocytogenes by Osebold Agglutination Test ( OAT). 112 sera of 205 were found as seropositive (%54.6) against Listeriosis. According to this study, Listeria monocytogenes was determined as a common disease in rams and ewes for sacrify in Ankara.
  • [ X ]
    Öğe
    Investigation of immunity against Bordetella pertussis in pregnant women and an overview of the vaccination schedule in Turkey
    (Turkish J Pediatrics, 2021) Gul, Serdar; Sonmez, Cemile; Ayvaz, Gokce; Kilic, Selcuk
    Background. Pertussis caused by Bordetella pertussis, is a disease leading to significant morbidity and mortality in neonates and infants. Direct protection of the infant may be achieved by maternal and neonatal vaccination. Despite primary vaccination, infants under six months pose the greatest risk of infection with pertussis. Maternal immunization provides a high level of infant protection from birth until immunity is achieved by active vaccination. There is no routine Tdap vaccination recommendation for pregnant women in Turkey. This study was carried out to determine pertussis antibody levels in pregnant women and provide data for improving vaccine planning. Methods. The study was carried out with 133 pregnant women in Turkey. Antibody titers to pertussis toxin (anti-PT) and filamentous hemagglutinin (anti-FHA) were measured by the commercially available ELISA. Results. Among 133 participants, 93 (69.9%) were found to be immune according to anti-PT IgG antibody levels. According to anti-FHA IgG antibody levels, 123 (92.5%) participants were considered to be immune. A positive correlation was observed between PT and FHA and the findings were statistically significant (P <0.001, r = 0.343). In the study group, the ages of the participants varied between 17 and 44 years. The mean age of those who were immune was 27.3 +/- 5.6, the mean age of non-immune patients was 29.1 +/- 6.2 and the difference was not statistically significant (P= 0.14). Conclusions. Our results reveal that approximately one-third of pregnant women were not immune to pertussis, reflecting many young infants to be vulnerable to pertussis infection until the onset of primary vaccinations, although childhood pertussis vaccination coverage has been high for a long time. We conclude that Tdap vaccine recommendation for pregnant women regardless of previous immunization history may be beneficial for the protection of infants in their first six months.
  • Küçük Resim
    Öğe
    Multiple-Locus Variable-Number Tandem-Repeat Analysis Genotyping of Human Brucella Isolates from Turkey
    (Amer Soc Microbiology, 2011) Kilic, Selcuk; Ivanov, Ivan N.; Durmaz, Riza; Bayraktar, Mehmet Refik; Ayaslioglu, Ergin; Uyanik, M. Hamidullah; Kantardjiev, Todor V.
    A multiple-locus variable-number tandem-repeat analysis (MLVA) was applied to investigate the epidemiological relationship and genetic diversity among 162 human Brucella isolates collected from all geographic regions of Turkey in an 8-year period (2001 to 2008). The isolates were genotyped by using an MLVA assay developed in Orsay, France (MLVA-16(Orsay)) including eight minisatellite (panel 1) and eight microsatellite (panel 2, subdivided into 2A and 2B) markers. Panels 1 and 2A distinguish 14 genotypes; two of these represented 85% of the strains. Panel 2B displayed a very high discriminatory power. Three loci from panel 2B had diversity index values higher than 0.74. MLVA-16(Orsay) yielded 105 genotypes; 73 were represented by a unique isolate, and 32 included two to eight isolates. The isolates from different patients within the same outbreak or from the same patient before first-line therapy and after relapse showed identical genotypes. A number of MLVA genotypes appeared to be partially restricted to some geographic areas and displayed no annual variation, possibly reflecting persistence of genotypes in certain areas for a time span of at least a decade. This study, representing the first molecular typing results of human Brucella isolates from Turkey, indicated that Turkish human Brucella melitensis isolates were most closely related to the neighboring countries' isolates included in the East Mediterranean group.