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  • Küçük Resim
    Öğe
    Associates Of Cognitive Functions In Aged Turkish Adults: Insights From A Psychiatry Outpatient Clinic
    (Gunes Kitabevi Ltd Sti, 2023) Kocakaya, Hanife; Öztürk, Hayriye Mihrimah
    Introduction: The aim of this study was to determine the cognitive function and its influential factors in elderly adults in Turkey. Materials and Methods: 127 patients aged over 65 years referred to a psychiatry outpatient clinic for the first time were included to cross-sectional and descriptive study. Patients were assessed by Carlson Comorbidity index, Montreal Cognitive Assessment Test, Geriatric Depression Scale, Beck Anxiety Inventory, Nottingham Health Profile and Lawton Instrumental Activities of Daily Living Scale.Results: The mean age of the patients was 69.7 & PLUSMN;4.2 years and 55.1% (n=70) of the participants were female. The primary diagnosis was Generalized Anxiety Disorder in 48.8% and Major depressive disorder in 51.2% of the patients. In multivariate analysis, age (OR:0.759, 95% CI:0.630-0.914, p=0.004), income <3800 TL (OR:14.72, 95% CI:1.78-121.51, p=0.013), medication usage (OR:0.171, 95% CI:0.035-0.845, p=0.030) and Geriatric Depression Scale score (OR:0.876, 95% CI:0.785-0.977, p=0.017) remained as independent predictors of Montreal Cognitive Assessment Test score.Conclusion: In Turkish adults with Generalized Anxiety Disorder or Major depressive disorder who admit to a psychiatry outpatient clinic for the first time, various parameters including age, education, income, leisure activity, medication usage, depression, Lawton Instrumental Activities of Daily Living Scale score and Nottingham Health Profile score are linked with cognitive impairment. However, only age, income, medication usage and depression independently associate with cognitive impairment in this highly specific patient population.
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    Öğe
    BİR ÜNİVERSİTE HASTANESİ PSİKİYATRİ POLİKLİNİĞİNE ADLİ YOLLA BAŞVURAN OLGULARIN RETROSPEKTİF İNCELENMESİ
    (2023) Kocakaya, Hanife; Özturan, Deniz Deniz
    Amaç: Adli psikiyatri, hukuk ve psikiyatrinin kesiştiği bir alan olup, yargı organlarına bilirkişilik boyutunda yardımcı olmaktadır. Bu çalışmada, adli psikiyatri polikliniğimizde değerlendirilen olguların sosyodemografik özellikleri, psikiyatrik tanıları, hangi amaçla adli psikiyatriye yönlendirildikleri ve değerlendirme sonucunda verilen kararların incelenmesi amaçlanmıştır. Gereç ve Yöntemler: Bu araştırma için 1 ocak 2020–1 mart 2023 yılları arasında psikiyatri polikliniği adli yolla başvuran hastaların sosyodemografik özellikleri, psikiyatrik tanıları ve isnat edilen suç özellikleri değerlendirilmek üzere tıbbi dosyaları araştırmacılar tarafından geriye dönük olarak taranmış ve tanımlayıcı istatistiksel analizler yapılmıştır. Bulgular: Çalışmamıza katılan olguların yaş ortalaması 37.06±8.19’ olup, katılımcılardan %75.7 (n=246)’sı erkek, %24.3 (n=79)’ü kadındı. Olguların psikiyatrik tanılarına bakıldığında; 94’ünde (%25.4) herhangi bir ruhsal bozukluk tanısı düşünülmedi, 83’ü (%25.5) için psikotik bozukluklar, 54’ü (%2) için zeka geriliği, 38’i (%12) için bipolar bozukluklar ve 16’sı (%4.9) için demans tanısı konuldu. Değerlendirilen adli olguların %23.7’sinin isnat edilen suçla ilgili olarak ceza sorumluluğunun tam olduğu, %18.5’inin TCK 32/1 kapsamında değerlendirildiği, %17.2’sine psikiyatrik hastalığı bulunmadığı yönünde rapor düzenlendiği, %5.5’inin TCK 32/2 kapsamında değerlendirildiği, %14.2’sine vasi atandığı,  % 5.8’ine gözlem kararı verildiği,  % 4.3’üne evlilik birliliğinin devamı hakkında görüş bildirildiği ve %10.8’ine ise vasi atanmasına gerek olmadığı yönünde görüş bildirilmiştir. Sonuç: Çalışmamız suç davranışı ve akıl sağlığı arasındaki ilişkiyi daha iyi anlama, ceza ve rehabilitasyon uygulamalarını iyileştirmeye yardımcı olma açısından literatüre katkı sağlamıştır.
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    Emotion dysregulation in migraine patients: can it be a hallmark the probability of the transformation from episodİc to chronic?
    (Taylor and Francis Ltd., 2023) Kocakaya, Hanife; Say, Bahar; Yörübulut, Serap; Ergün, Ufuk
    Objective: The main aim of this study was to examine patients with migraine in terms of emotional dysregulation and to evaluate whether the emotion dysregulation is effective on chronicity in migraine. Materials and Methods: A total of 85 migraine patients and 61 healthy participants were included in this study. All participants were evaluated using Migraine Disability Scale (MIDAS), Visual Analog Scale (VAS), Depression, Anxiety, and Stress Scale (DASS-21), Difficulties in Emotion Regulation Scale (DERS), Pain Catastrophizing Scale (PCS), and the Discomfort Intolerance Scale (DIS). Then, all results were compared between the migraine patients and healthy individuals. In addition, the migraine patients were separated into three groups as patients without an aura, patients with an aura and patients with chronic migraine and then their results were compared among them. Finally, the predictive markers of chronic migraine were explored using regression analyses. Results: Among 85 migraine patients, the mean age was 31.5 (SD = 7.98); 83.5% were women. The total and subscale scores of DERS, PCS, DIS, and DASS-21 were significantly higher in patients than in healthy individuals (p < 0.01). Subscale scores of DERS, DIS, and DASS-21 in the chronic migraine patients were found to be higher than in the other two patient groups (p < 0.01). Logistic regression analysis showed that chronic migraine could be associated with ‘lack of emotional clarity’ (OR = 1.229; p = 0.042), ‘lack of awareness’ (OR = 1.187; p = 0.032), ‘migraine associated disability’ (OR = 1.128; p = 0.033), and ‘stress’ (OR = 1.292; p = 0.027). Conclusion: This study results showed that chronic migraine could be associated with the emotional dysregulation. To our knowledge, this study is the preliminary study in the literature and, therefore, new studies with large samples are needed. © 2023 Informa UK Limited, trading as Taylor & Francis Group.
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    Öğe
    Emotion dysregulation in migraine patients: can it be a hallmark the probability of the transformation from episodIc to chronic?
    (Taylor & Francis Ltd, 2023) Kocakaya, Hanife; Say, Bahar; Yorubulut, Serap; Ergun, Ufuk
    ObjectiveThe main aim of this study was to examine patients with migraine in terms of emotional dysregulation and to evaluate whether the emotion dysregulation is effective on chronicity in migraine.Materials and MethodsA total of 85 migraine patients and 61 healthy participants were included in this study. All participants were evaluated using Migraine Disability Scale (MIDAS), Visual Analog Scale (VAS), Depression, Anxiety, and Stress Scale (DASS-21), Difficulties in Emotion Regulation Scale (DERS), Pain Catastrophizing Scale (PCS), and the Discomfort Intolerance Scale (DIS). Then, all results were compared between the migraine patients and healthy individuals. In addition, the migraine patients were separated into three groups as patients without an aura, patients with an aura and patients with chronic migraine and then their results were compared among them. Finally, the predictive markers of chronic migraine were explored using regression analyses.ResultsAmong 85 migraine patients, the mean age was 31.5 (SD = 7.98); 83.5% were women. The total and subscale scores of DERS, PCS, DIS, and DASS-21 were significantly higher in patients than in healthy individuals (p < 0.01). Subscale scores of DERS, DIS, and DASS-21 in the chronic migraine patients were found to be higher than in the other two patient groups (p < 0.01). Logistic regression analysis showed that chronic migraine could be associated with 'lack of emotional clarity' (OR = 1.229; p = 0.042), 'lack of awareness' (OR = 1.187; p = 0.032), 'migraine associated disability' (OR = 1.128; p = 0.033), and 'stress' (OR = 1.292; p = 0.027).ConclusionThis study results showed that chronic migraine could be associated with the emotional dysregulation. To our knowledge, this study is the preliminary study in the literature and, therefore, new studies with large samples are needed.
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    Evaluation of emotional dysregulation in patients with restless legs syndrome
    (Springer Japan Kk, 2023) Kocakaya, Hanife; Say, Bahar
    The aim of this study is to examine patients with restless legs syndrome (RLS) in terms of difficulty in emotion regulation and insomnia. A total of 52 patients with RLS and 57 healthy volunteers were enrolled. Difficulties in Emotion Regulation Scale Short Form (DERS-16), Insomnia Severity Index (ISI), Hospital Anxiety and Depression Scale (HADS), and International Restless Legs Syndrome rating scale were applied to participants. The mean age was 34.00 +/- 8.27 years in patients and 31.70 +/- 9.12 years in control. The scores of DERS-16, ISI, HADS-A, and HADS-D were significantly higher in the patients than the controls (p = 0.000). The DERS-16 total score showed a significant correlation with age (r = 0.404, p = 0.003), ISI (r = 0.281, p = 0.043), IRLS score (r = 0.422, p = 0.002), HADS-A (r = 0.409, p = 0.003), and HADS-D (r = 0.416, p = 0.002). The factors (age, gender, ferritin, ISI, and IRLS scores) that may be associated with the DERS-16 total scores were assessed with stepwise regression analysis. It was seen that the IRLSs variable had the most ability and could predict 45% (beta = 0.625, p < 0.001, increment R2 = 0.450) of difficulty in emotion regulation. In addition, the variable of insomnia could predict difficulty in emotion regulation by 17% (beta = 0.097, p = 0.001, increment R2 = 0.170). Patients with RLS may experience more emotion regulation difficulties than healthy controls. RLS severity and insomnia may be factors affecting emotion regulation difficulties in patients with RLS. According to our knowledge and our literature review, this finding seems to be the first report in the literature.
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    Evaluation of Patients Diagnosed with Generalized Anxiety Disorder in Terms of Early Maladaptive Schemas
    (2023) Kocakaya, Hanife; Ozturan, Deniz Deniz
    Aim: It has been reported that individuals with generalized anxiety have many interpersonal problems and these problems occur through schemas such as emotional inhibition, shyness, subjugation, self-sacrifice and intervention. In light of this information, the purpose of this study was to compare individuals with generalized anxiety disorder (GAD) and healthy controls in terms of early maladaptive schemas (EMSs). Material and Methods: This research involved 92 participants aged 18 to 55, including 48 GAD patients and 44 healthy controls. Sociodemographic data form, Young Schema Questionnaire-Short Form-3 (YSQ-S3), Generalized Anxiety Disorder 7-item scale (GAD-7), Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI) were administered to the participants. The study was approved by the ethics committee (KÜTF KAEK NO:2023.02.16). Results: The patients' average age was 38.19±11.29, and 83.3% of them (n=40) were women. The average age of healthy controls was significantly lower, however, neither group differed significantly in terms of education or marital status. The mean GAD-7 score of the patients was 6.26±6.81. Emotional deprivation (p=0.024), pessimism (p<0.001), approval seeking (p=0.034), self-sacrifice (p=0.004), punitiveness (p<0.001), abandonment (p<0.001), vulnerability (p=0.042) schema scores, and BAI (p<0.001) and BDI (p<0.001) scores were significantly higher in GAD group. Moreover, there was a positive correlation (p<0.05) between GAD-7 score and early maladaptive schemas (excluding failure, insufficient self-control and defectiveness). Conclusion: Our findings show that multiple EMSs play a role in patients with GAD. In this context, EMSs should be considered in the approach to patients with GAD, as it is one of the diseases that cause the most disability and is closely related to other psychological disorders.
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    Impact of biological rhythms on perception of illness and cognitive flexibility in bipolar patients in remission
    (Taylor & Francis Inc, 2024) Kocakaya, Hanife; Yetkin, Sinan
    Our study aims to examine the possible mediating effects of biological rhythms on the relationship between illness perception, cognitive flexibility, and functionality in bipolar patients in remission. A total of 150 patients with bipolar disorder (BD) were enrolled. The sociodemographic data form, Biological Rhythm Interview of Assessment in Neuropsychiatry (BRIAN), Brief Illness Perception Questionnaire (BIPQ), Cognitive Flexibility Scale (CFS), Young Mania Rating Scale, Montgomery and Asberg Depression Scale, Beck Anxiety Inventory, and Short Functionality Assessment Scale were applied to the patients in the study. The mean age of the patients was 42.10 +/- 12.92 (SD). The participants were 48.7% (n = 73) female and 66.6% (n = 100) BD-I. There was a negative correlation between the total BRIAN score and favorable BIPQ scores and a positive correlation between the total BRIAN score and unfavorable BIPQ scores (except timeline). Additionally, multiple regression analyses revealed that the total BRIAN score could predict favorable BIPQ (except treatment control) and unfavorable BIPQ (except timeline) scores (p < 0.05). The total CFS score also could predict favorable BIPQ (treatment control) and unfavorable BIPQ scores (except timeline). The second step mediation analysis showed that biological rhythm mediated the relationship between illness perception and cognitive flexibility. Our study found that biological rhythms played a full mediating role in the relationship between the perception of illness and cognitive flexibility. In addition, worsening in biological rhythms in bipolar patients could cause negative beliefs and attitudes towards their diseases with an unfavorable clinical course. Therefore, regularity in biological rhythms should be highly recommended for bipolar patients.
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    Peripheric and central olfactory measurements in patients with bipolar disorder
    (Sage Publications Ltd, 2023) Kocakaya, Hanife; Bayar Muluk, Nuray; Bekin Sarikaya, Pelin Zeynep
    Background Bipolar disorder (BD) is a mental health disorder. Purpose To investigate the peripheric and central olfactory measurements in patients with BD using magnetic resonance imaging (MRI). Material and Methods This study was conducted retrospectively. Group 1 consisted of 27 euthymic patients with BD (14 men, 13 women) and Group 2 consisted of 27 healthy controls (14 men, 13 women). Olfactory bulb (OB) volume and olfactory sulcus (OS) depth (peripheric), and corpus amygdala and insular gyrus area (central) measurements were performed using cranial MRI. Results OB volume and OS depth value of the bipolar group were lower than the control group, but there were no significant differences between the groups (P > 0.05). The corpus amygdala and left insular gyrus area of the bipolar group were significantly lower than those in the control group (P < 0.05). There were positive correlations between OB volumes and OS depths, the insular gyrus areas, and the corpus amygdala areas (P < 0.05). As the number of depressive episodes and duration of illness increased in bipolar patients, the depth of the sulcus decreased (P < 0.05). Conclusion In the present study a correlation was detected between OB volumes and the structures, known as emotional processing (e.g. insular gyrus area, corpus amygdala), and clinical features. Accordingly, new treatment techniques, such as olfactory training, may be considered an option in the treatment of such patients with BD.
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    The Relationship of Perceived Social Support with Level of Insight and Treatment Adherence in Individuals Diagnosed with Schizophrenia and Bipolar Disorder
    (2024) Kocakaya, Hanife; Arslan, Kübra; Buturak, Şadiye Visal; Turgal, Ebru
    Purpose: This study aims to examine the relationship between perceived social support, insight, and treatment adherence in patients with schizophrenia and bipolar disorder. Materials and Methods: This study was conducted with 110 individuals, including 55 bipolar and 55 schizophrenia patients, who had been hospitalized in our clinic in the last 1 year and were in remission. Participants were administered a sociodemographic and clinical data form, Young Mania Rating Scale (YMDÖ), Clinical Global Impression Scale (CGI), Three Components of Insight Rating Scale (IÜBDÖ), Morisky Treatment Compliance Scale (MTUÖ) and Multidimensional Perceived Social Support Scale (MSPSS). Results: The mean age was 40.47±12.96 for bipolar patients and 40.45±11.71 for schizophrenics. Perceived family, friend, significant others support, and total support was found to be higher (p=0.000, p=0.000, p=0.004, p=0.000, respectively) of bipolar patients, and the highest support was perceived from family, followed by friends and significant people. Although the groups did not differ in terms of treatment adherence (p=0.083), the insight score was significantly higher in bipolar patients (p=0.001). Groups were evaluated with hierarchical regression analysis in terms of factors affecting perceived social support. Gender, years of education, insight, and treatment adherence were found to be predictive of social support (p=0.04, p=0.01, p<0.001, p=0.01, respectively). Conclusion: Informing caregivers (family, etc.) of bipolar and schizophrenic patients about the effect of social support on clinical outcome may reduce the burden of caregivers by contributing positively to insight and treatment compliance.