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    DEPRESSION AND ANXIETY IN PATIENTS WITH MIGRAINE AND TENSION-TYPE HEADACHE
    (Gazi Univ, Fac Med, 2005) Tan, Funda Uysal; Ozen, Nurper Erberk; Kazezoglu, Saziye; Kokoglu, Fatma; Boratay, Cumhur
    Purpose: The identifi cation of headache patients who are at risk for psychiatric comorbidity is an important quality of life and prognostic issue. The purpose of this study was to assess psychiatric comorbidity in TTH and migraine patients. Materials and Methods: The study group included 95 (75 female, 20 male) patients diagnosed with either migraine or TTH. All patients were requested to fi ll out a 44-item symptom list constructed according to DSM-IV diagnostic criteria for depression and anxiety disorders and to complete the Beck Depression Inventory (BDI) and Spielberger State-trait Anxiety Inventory (STAI). After that all patients were evaluated for the presence of psychiatric disorders according to DSM-IV criteria. Results: Fifty-one (53.7%) patients had migraine while 44 (46.3%) had TTH and their mean ages were 32.77 +/- 7.8 and 30.32 +/- 9.4 years, respectively (p=0.11). The overall intensity levels of symptoms related to depression and anxiety were similar in both migraine and TTH patients. However, reduced libido (p=0.02), slowness (p=0.04) and nausea (p=0.003) were more intense in migraine patients. The mean BDI, SAI and TAI scores were elevated to the pathologic range in both migraine and TTH patients despite the absence of a signifi cant difference between the groups. The incidences of depression, anxiety and depression+anxiety were 37.3%, 15.7% and 9.8%, respectively, in migraine patients and 43.2%, 9.1% and 6.8%, respectively, in TTH patients (p=0.92). Conclusion: Depression and anxiety disorders are common and generally similar in extent and distribution in migraine and TTH patients.
  • Küçük Resim
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    Dorsal Sural Nerve Conduction Study in Early Diabetic Polyneuropathy Patients and Relationship of Adiponectin and High Sensitive-C Reactive Protein Levels
    (Journal Neurological Sciences, 2009) Kokoglu, Fatma; Leventoglu, Alev; Erdemoglu, A. Kemal
    Objective: In this study, we aimed to investigate the change in dorsal sural nerve (DSN) conduction studies in early diabetic neuropathic patients and to evaluate whether high sensitive C-reactive protein (hs-CRP), inflammatory marker, and adiponektin, important role in insulin resistance and diabetes, have any effect on DSN studies or not. Material and Method: Forty-six patients with early stages (Dyck classification N1)diabetic neuropathy and age-sex matched forty-four control subject were included in the study. Informed consent was obtained after approval of ethical committee. In all subject DSN conduction studies were performed with conventional electrophysiological studies. DSN electrophysiological parameters of diabetics were compared with controls. The relationship between plasma adiponectin and hs-CRP levels and DSN conduction study parameters were analyzed. Results: In diabetic patients, DSN parameters were significantly different than controls. The level of adiponectin was found to be lower in diabetic (p:0.01) but not statistically significant for hs-CRP levels (p:0.40). There was not any relationship between DSN parameters and the level of adiponectin or hs-CRP (p>0.05). Sixty-three % of diabetics, whom routine electrophysiological studies were in normal limits, had abnormal DSN parameters. Fifty% of diabetics had bilateral abnormalities. However, there was no difference in hs-CRP and adiponectin levels between patients with abnormal and normal DSN studies (p>0.05). Conclusion: DSN studies are useful methods to detect subclinical early diabetic polyneuropathy according to the results of our study. Although adiponectin level was found lower in early diabetic neuropathic patients, both adiponectin and hs-CRP do not have any relationship with DSN studies.