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  • Küçük Resim
    Öğe
    Do electrophysiological findings differ according to the clinical severity of carpal tunnel syndrome?
    (2006) Leventoğlu, Alev; Kuruoğlu, Reha
    Amaç: Klinik olarak orta ve şiddetli karpal tünel sendromu (KTS) olan gruplar arasındaki elektrofizyolojik (EMG) farklılıkları değerlendirmek. Hastalar ve Metod: KTS’si olan 226 hastada retrospektif olarak 385 el EMG çalışmaları ile değerlendirildi. Italyan KTS çalışma grubunun modifiye edilen kriterlerine gore klinik tutulumları orta ve şiddetli olarak ikiye ayrıldı. Sinir iletim çalışmaları da yine aynı grubun modifiye edilmiş kriterlerine gore orta ve şiddetli olarak klasifiye edildi. Iğne EMG bulguları da analiz edildi. Bulgular: Klinik ve elektrofizyolojik evreleme arasında iyi koralasyon saptandı (p 0.01). Klinik olarak orta ve şiddetli gruplar arasında nörofizyolojik tutulumun şiddeti arasında önemli fark izlenmedi (p0.07). Bununla birlikte iğne EMG anormalliği (p0.01) ve uzamış median F dalga latansı (p0.01) klinik olarak şiddetli grupta anlamlıydı. Ulnar sinir duyu iletim anormallikleri sadece orta derecede etkilenmiş grupta izlendi. Sonuçlar: Bu sonuçlar göstermektedir ki elektrofizyolojik değerlendirme patolojiyi yansıtan oldukça duyarlı yöntem olup klinik tutulumun şiddetinden bağımsızdır.
  • Küçük Resim
    Öğe
    Effect of paralysis of the abdominal wall muscles by botulinum A toxin to intraabdominal pressure: an experimental study
    (W B Saunders Co-Elsevier Inc, 2006) Çakmak, Murat; Cağlayan, Fatma; Somuncu, Salih; Leventoğlu, Alev; Ulusoy, Sevgi; Akman, Hülya; Kaya, Murat
    Purpose: To show the effect of botulinum A toxin-induced paralysis of abdominal muscles oil intraabdominal pressure. Material and Methods: Fifteen Sprague-Dawley rats were divided into 2 groups. An abdominal skin incision was done, and 2 catheters were placed for the pressure monitoring and saline infusion. Saline Solution was given to the abdomen until reaching to a pressure level of 9 cm H2O and 6 min Hg in pressure device, and the amounts of injected saline were recorded. Then intraabdominal saline was drained. Two milliliters (5 U/mL) botulinum A toxin was applied to the abdominal muscles in group 2. Saline was injected at the same points in same amounts in group 1. After 3 days, catheters were placed, and the saline volumes needed to obtain the same pressure levels were recorded for each rat. Spontaneous motor unit potential (MUP), single MUP analysis and interference patterns of the muscles, respiratory rates, and vascular pressure measurements were recorded before and after botulinum toxin (Botox) injections. Results: Mean intraabdominal saline volumes in the first and third days were 63.8 and 64.4 mL in group 1 and 67.6 and 80.6 mL in group 2, respectively. Mean MUP amplitude and duration of the rectus muscles in group 2 (17.1 mu V and 1.47 milliseconds) were significantly lower than those of group I (187 mu V and 4.9 milliseconds) in the third day. There were no pathological changes in respiratory rates and pressure measurements before and after Botox injections. Conclusion: This pilot experimental study showed that local injection of botulinum A toxin causes paralysis in abdominal wall muscles, increases the intraabdominal volume, and decreases the pressure, and this application may be used as ail adjunct in abdominal Wall Closure in selective cases. (c) 2006 Elsevier Inc. All rights reserved.
  • Küçük Resim
    Öğe
    Ovarian reserve assesment in patients with multiple sclerosis
    (Elsevier Science Inc, 2010) Çil, Aylin Pelin; Leventoğlu, Alev; Sönmezer, Murat; Uzdoğan, Andaç; Güler, Zuhal Beyza; Oktay, Kultuk
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