Yazar "Lotti, Torello" seçeneğine göre listele

Listeleniyor 1 - 6 / 6
  • Küçük Resim
    Öğe
    A Case of COVID-19 in a Patient with Pemphigus Successfully Managed with Favipiravir
    (Duzce Univ, Fac Medicine, 2021) Demirbaş, Abdullah; Elmas, Ömer Faruk; Supsup, Mustafa Atasoy; Demirbaş, Gözde Ulutaş; Tursen Ümit; Lotti, Torello; Kilitci, Asuman
    COVID-19 is not only a respiratory disease, but a multisystem disease that can cause organ dysfunction and coagulation disorder associated with high mortality and morbidity, particularly in vulnerable populations. Severe complications can be seen especially in elderly patients with systemic disease and immunosuppressive patients. We present the case of COVID-19 that developed in a 38-year-old female patient with pemphigus successfully managed with favipiravir.
  • [ X ]
    Öğe
    COVID-19 and human papillomavirus: Paradoxical immunity
    (Wiley, 2021) Demirbas, Abdullah; Eker, Hediye; Elmas, Omer Faruk; Ulutas Demirbas, Gozde; Atasoy, Mustafa; Tursen, Umit; Lotti, Torello
    Coronavirus disease 2019 (COVID-19) is a multisystemic disease that can cause progressive lung failure, organ dysfunction, and coagulation disorder associated with high mortality and morbidity. COVID-19 is known to either primarily cause skin symptoms or increase existing skin diseases. Human papillomavirus (HPV) is a DNA virus that can cause benign and malignant neoplasms. Mucocutaneous verruca vulgaris are common benign lesions of HPV. Here, we report a case of verruca vulgaris regressed after COVID-19.
  • [ X ]
    Öğe
    Potential utility of oral mucosal capillaroscopy as an indicator of microvascular damage in Behçet disease: A preliminary study
    (Mattioli 1885, 2021) Demirbaş, Abdullah; Elmas, Ömer Faruk; Demirbaş, Gözde Ulutaş; Atasoy, Mustafa; Türsen, Ümit; Lotti, Torello
    Introduction: Behçet disease (BD) is an auto-inflammatory condition characterized by multisystemic vasculitis. Oral mucosal capillaroscopy is an easy-to-use, repeatable, non-invasive method for evaluating mucosal microvasculature, contributing to the differential diagnosis and prognosis of various acute and chronic inflammatory diseases. Objectives: This study aims to characterize and describe the oral labial mucosal capillary findings in patients with BD using handheld dermatoscopy and to investigate the relationship between the capillary findings and the severity of the disease. Methods: This cross-sectional study included patients with BD and healthy subjects. Capillaroscopic examination of the oral labial mucosa in each subject was performed by a handheld dermatoscope using polarized light. The clinical severity of BD was evaluated using Krause's Clinical Severity Scoring for BD. Results: Sixty patients with BD and 60 healthy subjects were enrolled in the study. The frequencies of irregular capillaries, microhemorrhages, glomerular vessels, megacapillaries, and tortuous vessels were statistically significantly higher in the patient group when compared to the healthy individuals. In addition, a correlation was detected between the oral mucosal capillaroscopic findings and disease duration, severity, and vascular complications. Conclusions: Our study is the first to explore the potential role of oral mucosal capillaroscopic examination in patients with BD. Data obtained from this study indicated that oral mucosal capillaroscopy may be a useful tool to demonstrate microvascular damage in patients with BD. © 2021 Demirbaş et al.
  • [ X ]
    Öğe
    Potential Utility of Oral Mucosal Capillaroscopy as an Indicator of Microvascular Damage in Behcet Disease: A Preliminary Study
    (Mattioli 1885, 2021) Demirbas, Abdullah; Elmas, Omer Faruk; Demirbas, Gozde Ulutas; Atasoy, Mustafa; Tursen, Umit; Lotti, Torello
    Introduction: Behcet disease (BD) is an auto-inflammatory condition characterized by multisystemic vasculitis. Oral mucosal capillaroscopy is an easy-to-use, repeatable, non-invasive method for evaluating mucosal microvasculature, contributing to the differential diagnosis and prognosis of various acute and chronic inflammatory diseases. Objectives: This study aims to characterize and describe the oral labial mucosal capillary findings in patients with BD using handheld dermatoscopy and to investigate the relationship between the capillary findings and the severity of the disease. Methods: This cross-sectional study included patients with BD and healthy subjects. Capillaroscopic examination of the oral labial mucosa in each subject was performed by a handheld dermatoscope using polarized light. The clinical severity of BD was evaluated using Krause's Clinical Severity Scoring for BD. Results: Sixty patients with BD and 60 healthy subjects were enrolled in the study. The frequencies of irregular capillaries, microhemorrhages, glomerular vessels, megacapillaries, and tortuous vessels were statistically significantly higher in the patient group when compared to the healthy individuals. In addition, a correlation was detected between the oral mucosal capillaroscopic findings and disease duration, severity, and vascular complications. Conclusions: Our study is the first to explore the potential role of oral mucosal capillaroscopic examination in patients with BD. Data obtained from this study indicated that oral mucosal capillaroscopy may be a useful tool to demonstrate microvascular damage in patients with BD.
  • [ X ]
    Öğe
    The role of oxidative stress in onychomycosis: Thiol/disulphide homeostasis
    (Wiley, 2021) Metin, Mahmut Sami; Elmas, Omer Faruk; Demirbas, Abdullah; Erel, Ozcan; Atasoy, Mustafa; Tursen, Umit; Lotti, Torello
    Objectives Onychomycosis is the general term to define fungal nail infections that arise from dermatophytes, non-dermatophytic moulds and yeasts. Thiol/disulphide homeostasis is a new indicator of oxidative stress. In this study, we aimed to investigate the role of thiol/disulphide balance in the pathogenesis of onychomycosis. Methods This cross-sectional study included adult patients with onychomycosis who were admitted to the dermatology department and healthy adult volunteers without any dermatologic or systemic condition. The patients and controls were evaluated in terms of native thiol, total thiol, and disulphide levels, and disulphide/native thiol, disulphide/total thiol and native thiol/total thiol ratios. The possible association between these parameters and clinical subtypes of onychomycosis and demographic characteristics was also investigated. Results A total of 52 patients with onychomycosis and 50 healthy subjects were enrolled in the study. The patient group showed lower levels of total thiol, native thiol and native thiol/total thiol ratio, and higher ratios of disulphide/native thiol and disulphide/total thiol. No statistically significant relationship was found between the parameters, clinical subtypes of onychomycosis and demographic characteristics (p > .05). Conclusion Patients with onychomycosis showed a shifted thiol/disulphide homeostasis towards oxidative stress with a reduction in thiols and an increase in disulphide/native thiol, and disulphide/total thiol ratios. These findings may indicate the role of oxidative stress in the pathogenesis of onychomycosis.
  • [ X ]
    Öğe
    Therapeutic efficacy and safety of three different modalities in pediatric patients with plantar warts
    (Wiley, 2021) Acar, Emine Muge; Uyar, Belkiz; Elmas, Omer Faruk; Ozyurt, Kemal; Atasoy, Mustafa; Tursen, Umit; Lotti, Torello
    Human papillomavirus infection is relatively common in communities. Thus, determining an effective and painless treatment method, especially in pediatric patients is of utmost importance. This study aimed to compare the outcomes of three different methods of treating plantar warts in pediatric patients. Children with verruca plantaris treated with a salicylic acid-lactic acid combination once daily (SA/LA 1), a salicylic acid-lactic acid combination applied in three to seven layers under occlusion every 3 days (SA/LA 2), or a combination of 5-fluorouracil (0.5%) and salicylic acid (10%) (SA/5-FU) were evaluated retrospectively. Treatment responses and recurrence rates were also evaluated after a minimum of 4 months. Among the 98 children with verruca plantaris, 19 were treated with SA/LA 1, 53 were treated with SA/LA 2, and 18 were treated with SA/5-FU; the eight patients who received cryotherapy were excluded. The mean treatment duration was significantly shorter in the SA/LA 2 group than in the SA/LA 1 group and the SA/5-FU group. (p = 0.000 for both) Application of a salicylic acid-lactic acid combination in multiple layers under occlusion is a safe, painless, and effective treatment method for plantar warts in children.