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    Detection of hand osteoarthritis from hand radiographs using convolutional neural networks with transfer learning
    (TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY, 2020) Ureten, Kemal; Erbay, Hasan; Maras, Hadi Hakan
    Osteoarthritis is the most common type of arthritis. Hand osteoarthritis leads to specific structural changes in the joints, such as asymmetric joint space narrowing and osteophytes (bone spurs). Conventional radiography has traditionally been the primary method of visualizing these structural changes and diagnosing osteoarthritis. We aimed to develop a computerized method that is capable of determining the structural changes seen in radiography of the hand and to assist practitioners in interpreting radiographic changes and diagnosing the disease. In this retrospective study, transfer-learning-based convolutional neural networks were trained on a randomly selected dataset containing 332 radiography images of hands from an original set of 420 and were validated with the remaining 88. Multilayer convolutional neural network models were designed based on a transfer learning method using pretrained AlexNet, GoogLeNet, and VGG-19 networks. The accuracies of the models were 93.2% for AlexNet, 94.3% for GoogLeNet, and 96.6% for VGG-19. The sensitivities of these models were 0.9167 for AlexNet, 0.9184 for GoogLeNet, and 0.9574 for VGG-19, while the specificity values were 0.9500, 0.9744, and 0.9756, respectively. The performance metrics, including accuracy, sensitivity, specificity, and precision, of our newly developed automated diagnosis methods are promising in the diagnosis of hand osteoarthritis. Our computer-aided detection systems may help physicians in interpreting hand radiography images, diagnosing osteoarthritis, and saving time.
  • Küçük Resim
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    Detection of rheumatoid arthritis from hand radiographs using a convolutional neural network
    (SPRINGER LONDON LTD, 2020) Ureten, Kemal; Erbay, Hasan; Maras, Hadi Hakan
    Introduction Plain hand radiographs are the first-line and most commonly used imaging methods for diagnosis or differential diagnosis of rheumatoid arthritis (RA) and for monitoring disease activity. In this study, we used plain hand radiographs and tried to develop an automated diagnostic method using the convolutional neural networks to help physicians while diagnosing rheumatoid arthritis. Methods A convolutional neural network (CNN) is a deep learning method based on a multilayer neural network structure. The network was trained on a dataset containing 135 radiographs of the right hands, of which 61 were normal and 74 RA, and tested it on 45 radiographs, of which 20 were normal and 25 RA. Results The accuracy of the network was 73.33% and the error rate 0.0167. The sensitivity of the network was 0.6818; the specificity was 0.7826 and the precision 0.7500. Conclusion Using only pixel information on hand radiographs, a multi-layer CNN architecture with online data augmentation was designed. The performance metrics such as accuracy, error rate, sensitivity, specificity, and precision state shows that the network is promising in diagnosing rheumatoid arthritis.