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Öğe Case 3: Fetal intracardiac tumour - A feature of a genetic disease? - Diagnosis: Tuberous sclerosis(Wiley, 2006) Misirlioglu, Emine Dibek; Aliefendioglu, Didem; Alpan, Nursel; Güven, Alev; Peltek, Nur…Öğe Clinical and etiologic evaluation of the children with chronic urticaria(Ocean Side Publications Inc, 2016) Azkur, Dilek; Civelek, Ersoy; Toyran, Muge; Misirlioglu, Emine Dibek; Erkocoglu, Mustafa; Kaya, Aysenur; Kocabas, Can NaciBackground: Chronic urticaria (CU) is a skin disorder defined as daily or almost daily exhibition of pruritic and transient wheals that last for >6 weeks. CU is divided into two subtypes: chronic spontaneous urticaria (CSU) and chronic inducible urticaria (CIndU). Objectives: To evaluate the clinical features, possible causes, associated findings, and laboratory results of different subtypes of CU in children according to a new classification. Methods: In this study, we evaluated the clinical features, laboratory investigations, and provocation tests of children with different subtypes of CU according to a new classification. Results: Two hundred and twenty-two children (59.9% girls) were enrolled in the study. Of the study patients, 59.9% and 40.1% were diagnosed as having CSU and CIndU, respectively. Antithyroid antibody levels were positive in 7.1% of the patients with CSU, 32.8% of the children had positive 14C-urea breath test results, and 6.5% of the patients had positive stool examination results for parasites. Autologous serum skin test results were positive in 53.5% of the patients with CSU. Of the patients with CIndU, 77.5% had symptomatic dermographism, 16.8% had cold urticaria, 2.2% had cholinergic urticaria, 2.2% had solar urticaria, and 1.1% had aquagenic urticaria. Conclusion: Children with CSU represent the majority of patients with CU, and more than a half of these patients might have autoimmune urticaria. Symptomatic dermographism was the most common type of CIndU.Öğe Do cerebral blood flow velocities change in iron deficiency anemia?(Lippincott Williams & Wilkins, 2007) Aliefendioglu, Didem; Yilmaz, Sevda; Misirlioglu, Emine Dibek; Saygi, Semra; Özdoğan, Selver; Koçak, ÜlkerInfants with iron deficiency had lower scores when tested for mental and motor development than their peers with better iron status. The aim of this study was to examine cerebral blood flow velocity in infants with iron deficiency anemia. Thirty-six infants (27 male, 9 female) with iron deficiency anemia, aged 6 to 36 months were divided into 2 groups according to the hemoglobin (Hb) values [group 1 (n = 23) Hb < 10 g/dL and group 2 (n = 13) 11 > Hb >= 10g/dL]. In anterior and middle cerebral arteries only end-diastolic velocity (EDV) was increased in group 1 as compared with group 2 (P = 0.05 and P = 0.016, respectively), whereas in posterior cerebral artery both EDV and peak-systolic velocity were different between the groups (P = 0.024 and P = 0.004). Both peak-systolic velocity and EDV showed significant correlation with Hb level in the posterior cerebral artery (r = -0.38, P = 0.023 and r = - 0.35, P = 0.037) but not in the anterior and middle cerebral arteries. Increased cerebral blood flow velocities in children with lower Hb values may be due to increased cardiac output, decreased vascular resistivity caused by anemia.Öğe Factors affecting reading habit and media follow-up in turkey(Gulhane Military Medical Academy, 2014) Bülbül, Selda Hizel; Misirlioglu, Emine Dibek; Ceyhun, Gulsen; Araz, Nilgun Col; Altug, UmitAIM: Reading habit in our country is quite below the world standards. In this study, the aim was to investigate reading habit, and media follow-up of Turkey in three distinct provinces. METHOD: The research group of this cross-sectional study was composed of stuff and students of medical schools, teachers and parents of the students of primary schools in three provinces. Data were obtained from questionnaires self-filled by 750 people. RESULTS: Of the people whose ages ranged from 16 to 65 (31.75±10.19) years, 28.7% were students, 14.1% were house-wives, and 7.9% were lecturers. They spent their leisure time mostly by watching TV (25.6%), playing video/internet games (9.9%), reading books (7.9%), and merely going to cinema/theater (16.7%). Of the group, 41.7% read ? 5 books per year, whereas 10.7% read no books at all. The reasons for not reading were lack of time (66.5%) and economical (10.8%). While 61.4% of those with very good economic status read >6 books per year, this rate was 22.2% among those with poor economic status, and the difference was significant (p=0.000). 32.4% were reading and 30.8% bought newspapers everyday. While 10.5% of primary school graduates bought newspapers every day, this rate was 48.9% among graduates of a university or a master degree (p=0.000). Seven percent of those with very good economic status bought no newspapers, whereas this rate was 43.1% among those with poor economic status (p=0.000). Of the people, 95.3% had a television at home. The most watched programs were the series (34.5%), and news programs (35.7%), respectively. 16.6% of the group did not listen to radio at all and the rest were listening only while driving or doing housework. CONCLUSION: Our study is important in terms of covering people from different sections of Turkish society and emphasizing the low reading habit and media follow-up once more.Öğe Helicobacter pylori infection in mother and infant pairs in Anatolia(Aves, 2010) Hizel, Selda; Ozden, Ali; Tanzer, Fatos; Kisa, Ucler; Misirlioglu, Emine Dibek; Buyukkayhan, Derya; Kisa, OzgulBackground/aims: The aim of this prospective study was to determine the seroprevalence rates of Helicobacter pylori in mother and infant pairs and to discuss the possible fecal-oral transmission route of Helicobacter pylori infection in the early years of life. Methods: Forty-eight mother-child pairs were followed for 12 months. Helicobacter pylori IgG and hepatitis A virus (HAV) IgG levels were measured in maternal sera, infant sera and breast-milk samples at birth and in breast-milk samples and infant sera at follow-up visits. Results: At birth, the rate of Helicobacter pylori positivity was 81.25% in breast-milk and 95.8% in maternal and infant sera. Although there was a decrease in seropositivity in both baby sera and breast-milk at the age of nine months, an increase was observed in the 12(th) month. Hepatitis A virus IgG was measured to show whether Helicobacter pylori and hepatitis A virus use the same transmission routes. Hepatitis A was positive in all infants' sera, in 95.8% of mothers' sera, and in 68.75% of breast-milk samples. Seropositivity rates in infants whose mothers were seropositive for Helicobacter pylori and hepatitis A virus decreased gradually. There was an increase after the 9(th) month of life. Conclusions: Helicobacter pylori seroprevalence rates are high in Anatolia. It is possible that the decrease in breastfeeding with increased introduction of supplemental foods may lead to an increased risk of exposure to Helicobacter pylori.Öğe Remembering the Importance of an Old Friend: History Taking in Preoperative Evaluation of Healthy Children: A Single Center Experience(Gazi Univ, Fac Med, 2016) Toprak, Sule; Kocak, Ulker; Misirlioglu, Emine Dibek; Sanli, Cihat; Albayrak, Meryem; Basar, HulyaObjective: To investigate the consequences of routine laboratory tests that lead to surgical delay or high cost in patients with a normal medical history and physical examination who undergo minor surgical interventions. Patients and Method: Files of 1,322 patients aged between 0-16 years that had undergone elective surgical intervention within six years were reviewed. Results: Of the 1,322 patients, 1,246 (94.3%) had normal physical examination and laboratory findings. Seventy-six children who had abnormalities in laboratory findings and physical examination were referred to pediatrics. Of the 76 pediatric referees, 42 (55.3%) were reevaluated and were diagnosed with upper respiratory tract infection (n=23; 30.2%), iron deficiency anemia (n=5; 6.5%), innocent murmur (n=4; 5.3%), thalassemia minor (n=2; 2.6%), lower respiratory tract infection (n=2; 2.6%), urinary tract infection (n=1; 1.3%), mumps (n=1; 1.3%), acute gastroenteritis (n=1; 1.3%), minimal aortic and tricuspid valve insufficiency (n=1; 1.3%), minimal aortic stenosis (n=1; 1.3%), atrial septal defect (n=1; 1.3%). Surgical interventions were delayed until the recovery of the infectious diseases. In 25 of the patients, repeated tests showed normal ranges after the second test; however nine (n=9) of the patients showed increased or decreased numbers of white blood cell counts and whose medical history and physical examination revealed signs and symptoms related to infection. Conclusion: Routine laboratory tests contribute little to preoperative evaluation of children with normal history and physical examination undergoing low grade surgery.Öğe TRADITIONAL CHILD CARE PROCEDURES IN AN ANATOLIAN CITY(Gazi Univ, Fac Med, 2009) Aliefendioglu, Didem; Hizel, Selda; Misirlioglu, Emine Dibek; Sanli, Cihat; Albayrak, Meryem; Oktay, AylaPurpase Traditional procedures as old as humanity are current issues in today's modern medicine. Social and cultural characteristics influencing child care behavior and some procedures could be detrimental to the baby. The aim of this study was to determine traditional child care procedures in the central Anatolian city of Kirikkale, a city established after extensive migration. Method: Randomly chosen mothers were asked to fill in a questionnaire. The sociodemographic characteristics and traditional practices of the mothers were assessed. The results were compared by using the chi-square test. The relationships between the traditional procedures used by the mothers and the age at marriage and educational status were analyzed with logistic regression models. Results: A total of 974 mothers aged 18-60 years were interviewed. Of these, 201 (43%) were less than 30 years old. The average age at marriage was 17 or younger for 29% of the group and the age at first pregnancy was 17 or younger in 16%. Forty-eight percent of all were using at least one traditional procedure. Swaddling was the most commonly used method (27.2%). These practices were seen at higher rates in women with education of less than eight years' duration, among those who had married at 17 years of age or younger, and among those for whom more than 10 years had passed since their last pregnancy (p<0.05). Conclusion: Traditional procedures for baby care are still in use today. However, procedures that may be harmful to the baby are used less often by younger and better educated mothers. This result indicates that educating mothers is crucial and that the social fabric has changed somewhat over the years.Öğe Transposition of the great arteries in a newborn whose mother was treated with carbamazepine during pregnancy(Turkish Soc Cardiology, 2007) Misirlioglu, Emine Dibek; Aliefendioglu, Didem; Dogru, M. Tolga; Sanli, Cihat; Oktay, Ayla…
