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Öğe Blood Chromium-Cobalt Levels In Patients After Total Knee Arthroplasty And Their Effect On The Retinal Nerve Fiber Layer And Macular Ganglion Cell Complex(LIPPINCOTT WILLIAMS & WILKINS, 2020) Ogurel, Tevfik; Serbest, Sancar; Ogurel, Reyhan; Tiftikci, Ugur; Olmez, YasarPurpose: To study blood cobalt (Co) and chromium (Cr) levels in patients who have undergone total knee arthroplasty and their effect on the retinal nerve fiber layer and macular ganglion cell complex. Methods: One hundred patients who had undergone total knee arthroplasty and 50 healthy individuals who had no implants were included in the study. The patients were separated into two groups based on how long ago the prosthesis had been implanted (Group 1: 1 to 5 years; Group 2: 5 to 10 years). After a complete ophthalmological examination, retinal nerve fiber layer and macular ganglion cell complex of the patients were evaluated with optical coherence tomography, performed on dilated pupils. To assess the metal ion levels of the patients, venous blood samples were drawn from each patient. Results: The mean age of the patients was 64.72 +/- 6.26 years in Group 1, 67.80 +/- 8.07 years in Group 2, and 63.42 +/- 7.90 years in the control group. In the comparison of age and sex, there were no statistically significant differences between the groups and the control group. Co and Cr levels were statistically higher in Group 1 and Group 2 compared with the control group (P < 0.001). Mean retinal nerve fiber layer thicknesses and mean macular ganglion cell complex thicknesses in Group 1 and Group 2 were statistically lower than in the control group. Conclusion: Levels of Co and Cr are higher in patients who undergone total knee arthroplasty than healthy subjects, and these higher levels were associated with changes in the retinal nerve fiber layer and macular ganglion cell complex.Öğe Congenital hypothyroidism in Rieger Syndrome(Taylor & Francis Inc, 2016) Ornek, Nurgul; Ogurel, Reyhan; Ornek, KemalRieger syndrome (RS) is a multiple malformation syndrome characterized by ocular manifestations and extraocular defects. Herein, we report a 9-year-old boy who exhibited Rieger Syndrome phenotype as well as congenital hypothyroidism which may be an underappreciated feature of RS.Öğe Retinopathy of prematurity, diagnosis and standardization of the evaluation(Gazi Eye Foundation, 2015) Yumusak, Erhan; Mutlu, Fatih Mehmet; Sarica, Umit; Ogurel, ReyhanRetinopathy of prematurity (ROP) has been one of the issues about which the specialists have most argued but not compromised to that extent since its first definition. Restricted examination area of the eyes of the premature babies and difficulty of performing examination, and difficulty in achieving sufficient pupil dilatation have precluded the standardization of diagnosis and treatment. Plus disease, defined in 1980 has been used as an important indicator in the diagnosis and treatment of ROP. With a later revision, concepts such as preplus or threshold have been defined, and changes in posterior pole have gained much more importance. Desire of the ROP specialists in using technology towards the diagnosis of plus disease and consensus about the diagnosis has significantly increased in the last 10 years. In this article it was aimed to review the up-to-date studies about the diagnosis and treatment of ROP and plus disease.