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    Erosive Lichen Planus Affecting the Gums: A Case Report
    (AVES, 2024) Bariş, Kubilay; Olgun, H. Ebru
    Oral lichen planus (OLP) is a more common autoimmune inflammatory disease than other dermatoses. It causes symptoms such as painful ulcers and a burning sensation, prompting the patient to seek help from a health-care provider. While it occurs clinically in various forms, the reticular form is the most common. Oral lichen planus is considered by many researchers to be a premalignant condition. The purpose of this case report is to discuss the clinical features of OLP. © 2024, AVES. All rights reserved.
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    Evaluation of Neutrophil Extracellular Trap Formation on Smokers and Non-Smokers with Periodontitis
    (2024) Ocak, Gizem Yücesoy; Olgun, H. Ebru; Yıldız, Kader; Goksuluk, Merve Basol
    Objective: In this study, we aimed to evaluate neutrophil extracellular trap (NET) in smoker and non-smoker periodontitis patients. Materials and Methods: 21 subjects [non-smokers and periodontally healthy (S-P-) 7 people, non-smokers with periodontitis (S-P+) 7 people, smokers with periodontitis (S+P+) 7 people] were included in this study. Plaque index (PI), gingival index (GI), probing depth (PD) and clinical attachment level (CAL) parameters were recorded. The peripheral neutrophils isolated from the subjects were activated by phorbol 12-myristate 13-acetate (PMA) to induce NET formation. NET formed after the activation was measured with the fluorometer. Results: In the S-P- group PI, GI, PD and CAL values were found statistically significantly low (P=0,001; P=<0,001; P=0,003; P=<0,001, respectively). When compared to S+P+ group PMN counts were found low, but this difference was statistically at the border (P=0,05). When compared NET count values, it was the highest in the S+P+ group. When S-P- group and S+P+ group were compared, this difference was statistically significant (P=0,003); but between S-P+ and S+P+ groups, the difference was not statistically significant (P>0.05). NET count with PI, GI, PD, there was mild positive; with CAL strong positive relation has been found. Conclusion: As a result, even the S+P+ group NET count was found higher, the difference of S-P+ and S+P+ groups was not statistically significant. There is need more researches about smoking effect on NET formation in patients with periodontitis.
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    Smoking and Periodontal Health
    (Springer Science and Business Media B.V., 2018) Süme Keşir, S. Selva; Olgun, H. Ebru
    Purpose of Review: Smoking is a strong and modifiable risk factor for periodontitis. The adverse effects of smoking on oral health are at the center of long-term studies. The aim of this review is to assess these effects with new findings. Recent Findings: Studies in different populations have demonstrated strong associations between smoking and severity of periodontitis. Additionally, researchers have observed similar effects in various types of smoking such as water pipe smoking and smokeless tobacco. Microbiological analyses recently have shown increased early colonization of periodontal pathogens in smokers. Lower levels of immunoglobulins and impaired fibroblast attachment to matrix proteins are new observations. Smoking markedly influences response to treatment, and smokers are resistant to conventional periodontal therapy. Implant failure and risk of peri-implantitis are higher among smokers. Summary: Latest data supports that severity of periodontitis is higher in smokers. Smoking cessation is beneficial for improving periodontal status and periodontal therapy outcomes. © 2018, Springer International Publishing AG, part of Springer Nature.