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Yazar "Osmanoğlu, Gökhan" seçeneğine göre listele

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    Diaphragmatic Injuries: A Surgical Challenge. Report of Forty-one Cases
    (Georg Thieme Verlag Kg, 2009) Özpolat, Berkant; Kaya, Oskay; Yazkan, Rasih; Osmanoğlu, Gökhan
    Background: We present a discussion of the management of diaphragmatic injury and the factors that influence the choice of surgical approach based on our experience and a review of the literature. Methods: Data of 41 patients with diaphragmatic injuries treated between 1996 and 2007 were analyzed retrospectively. Results: A total of 29 men and 12 women between 15 and 56 years of age (mean age 34) were included in the study. Twenty-one patients had penetrating injuries and 20 patients had blunt injuries. The diagnosis was done preoperatively in 21 cases and intraoperatively in 20 cases. Thoracotomy was used in 23 cases, laparotomy in 11 cases, laparotomy-thoracotomy in 5 cases, sternotomy-laparotomy in 1 case, and sternotomy in 1 case. Emergency surgery was performed in 30 cases. Five cases were operated within 24 hours after admission to the emergency department. In 6 cases, surgery was performed 6 months to 4 years after the initial trauma. The mortality rate was 14.6% and the operative morbidity was 2.4%. Conclusion: A high index of suspect is vital for the diagnosis of diaphragmatic injuries in an emergency setting. The type of approach is closely related to the associated injuries.
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    Esophageal and Gastric Smooth Muscle Activity After Carbon Dioxide Pneumoperitoneum
    (Academic Press Inc Elsevier Science, 2010) Soyer, Tutku; Aktuna, Zuhal; Aydos, Tolga Reşat; Osmanoğlu, Gökhan; Korkut, Oğuzhan; Akman, Hülya; Çakmak, Murat
    Background. The metabolic changes associated with carbon dioxide (CO(2)) pneumoperitoneum include metabolic acidosis and lowered intra-abdominal pH values. An experimental study was performed to evaluate the effect of CO(2) pneumoperitoneum on esophageal and gastric smooth muscle sensitivity in response to several agonists. Methods. Wistar albino rats, weighing 200-250 g, were allocated into three groups. After anesthetization with ketamine hydrochloride and xylazine, abdominal esophagus, gastroesophageal junction, and gastric fundus were removed via median laparotomy in the control group. In the oxygen (O(2)) group, a 16G catheter was inserted into the abdomen above the umbilicus and insufflated with 95% O(2) and 5% CO(2) with a pressure of 10 mm Hg. In the CO(2) group, CO(2) was insufflated at the same pressure within the same time and the tissues were removed at the end of a 60 min period of pneumoperitoneum. Abdominal esophageal segment (n:6), gastroesophageal junction (n:6) and gastric fundus (n:12) were suspended under 0.5 to 2 g resting tension in Tyrode solution in organ baths. Contraction responses were obtained by carbachol and serotonin and relaxation responses were evaluated by isoproterenol in each group. All the responses were compared by nonparametric Kruskal Wallis test. Results. Carbachol and serotonin induced contractile responses of abdominal segments, gastroesophageal junction, and gastric fundus showed no difference between the control, O(2), and CO(2) groups (P > 0.05). Isoproterenol relaxation responses of the three groups were also not statistically different from each other (P > 0.05). Conclusion. CO(2) pneumoperitoneum of 60 min has no influence on esophageal and gastric smooth muscle responses to different agonists in rats. (C) 2010 Elsevier Inc. All rights reserved.

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