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    Illness Intrusiveness Ratings Scale: Translation, Reliability, and Validation Study of the Turkish Version
    (Sage Publications Inc, 2023) Sahin, Ferit; Cigdem Karacay, Basak; Ozturk, Hayriye Mihrimah
    The Illness Intrusiveness Ratings Scale (IIRS) is a useful, easy-to-apply tool that measures the degree of illness-induced disruptions in the 13 different aspects of life. The main aim of this study is to examine the validity and reliability of the Turkish version of IIRS and provide a new tool to investigate the impact of chronic illnesses in the Turkish population. A total of 376 patients with hypertension, diabetes, and/or osteoarthritis were recruited in this study. Patients completed the survey that consisted of the sociodemographic data, the Turkish translation of the IIRS, and the World Health Organization Quality of Life-Brief Form. The exploratory factor analysis yielded a three-factor structure, instrumental, intimacy, and relationship and personal development, which accounted for 59.9% of the total variance. Confirmatory factor analysis verified the three-factor structure. The IIRS was inversely correlated with the physical, psychological, and social health domains of quality of life. Our findings corroborate the reliability and validity of the Turkish version of the Illness Intrusiveness Ratings Scale. It can be used by healthcare practitioners to measure the illness-induced disruptions of lifestyles, activities, and interests.
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    Left atrial function index and left atrial electromechanical functions in anxiety disorders
    (Taylor & Francis Ltd, 2024) Ozturk, Hayriye Mihrimah; Erdogan, Mehmet; Turan, Yasar; Celik, Ibrahim Etem; Ozturk, Selcuk
    BackgroundThere is a close linkage between anxiety disorders (ADs), and development of cardiovascular disease (CVD) and atrial fibrillation (AF). We aimed to investigate left atrial function index (LAFI) and its components, LA mechanical functions and atrial conduction times in AD patients and age- and gender-matched control group patients for the first time in the literature.MethodsA total of 48 AD patients and 33 healthy subjects were enrolled to the study prospectively. Echocardiographic parameters including two-dimensional conventional echocardiography, diastolic functions, LA mechanical functions, LAFI, atrial conduction times and atrial electromechanical delay (AEMD) were calculated.ResultsThe velocity-time integral of the LV outflow tract (LVOT-VTI), LAFI and LA conduit volume were significantly lower in AD patients. Atrial electromechanical coupling as established from lateral mitral annulus (PA lateral) was significantly higher in AD group than control group. Inter-AEMD and left intra-AEMD were also higher in AD group compared to control group. Age, gender, body surface area (BSA), conduit volume, LVOT-VTI and LAFI were significant factors associated with AD in univariate analysis. However, only BSA and LVOT-VTI (Odds ratio [OR]: 0.79, 95 CI%: 0.66-0.95, p = 0.013) were independently associated with AD in multivariate analysis. Age, gender, conduit volume and LAFI (OR: 0.25, 95 CI%: 0.03-2.12, p = 0.204) were not found to be independent associates of AD.ConclusionLAFI is impaired in patients suffering from AD compared to their age- and gender-matched counterparts but this impairment originates from lower levels of LVOT-VTI calculations in AD patients. Thus, LVOT-VTI, but not LAFI, is independently associated with AD.
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    The association between total cholesterol and cognitive impairment in chronic obstructive pulmonary disease patients
    (Elsevier Science Inc, 2023) Ozturk, Hayriye Mihrimah; Ogan, Nalan; Erdogan, Mehmet; Akpinar, Evrim Eylem; Ilgar, Ceren; Ozturk, Selcuk
    Aim: Chronic obstructive pulmonary disease (COPD) is primarily a respiratory system disorder associated with extrapulmonary conditions. Cognitive impairment (CoI) is very common among COPD patients This study sought to investigate the association between CoI and clinical parameters, inflammatory markers and lipid profiles in a COPD patient population.Methods: The study population included 111 stable COPD patients. COPD was diagnosed according to Global Initiative for Chronic Obstructive Lung Disease guideline. Total complete blood count test and biochemical measurements including lipid profile were performed. Afterwards, all patients underwent neuropsychological assessment including Hospital Anxiety and Depression Scale (HADS), Pittsburgh Sleep Quality Index and Mon-treal Cognitive Assessment (MoCA) tests.Results: The patients were categorized into two groups according to their MoCA test score: MoCA score & LE; 21 (CoI) (n = 69) and MoCA score > 21 (normal cognition) (n = 42). Total cholesterol (TC) levels were significantly lower in patients with CoI compared to patients with normal cognition. Inflammation related parameters including C -reactive protein were similar among groups. Multivariate logistic regression analysis yielded education, HADS score and TC (OR:1.02, 95% CI:1.00-1.04, p = 0.025) as independent predictors of MoCA score.Conclusion: TC independently associates with CoI in COPD patients. There is comparable inflammatory status in COPD patients with CoI compared to COPD patients with normal cognition.