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    The Effect of Chronic Otitis Externa-Media on Brainstem Auditory Evoked Potentials in Dogs
    (Veterinarni A Farmaceuticka Univerzita Brno, 2008) Beşaltı, O.; Sirin, Y. S.; Pekcan, Z.
    The objective of the study was to present normative Brainstem Auditory Evoked Potentials (BAEP) data elicited by both air-conducted clicks (30 100 dBHL) and bone conducted clicks (100 1.30 dBHL) for healthy dogs, and dogs with chronic otitis externa-media (COEM). The data were analyzed to acquire reference values in 55 normal dogs and to estimate the degree of hearing, impairment associated with the disease. Filly-four dogs with COLM were divided into two degrees of security. The first one included dogs with severe (n 16), and the second with moderate COFM (n 38). The recognisability wave V was found higher than the others at every stimulation level. Wave VII was not seen by the bone-conducted click at all stimulation levels. and also in cases with severe COLM by the air.-conducted click. Recognisability of wave V was seen more than 50%, at 60 dBHL in severe COEM. This ratio was seen at 30 dBHL in moderate COLM. In healthy dogs, the latencies of waves (I VII) were compared between the left and the right side, and there were no significant differences between each side except tiff I shorter latency of wave VI. In conclusion, COEM caused increasing latency rather than total deafness, and BAFP can be suggested as an ancillary diagnostic tool in car disorders.
  • Küçük Resim
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    Polylactic acid and polyethylene glycol prevent surgical adhesions
    (Comenius Univ, 2016) Ozpolat, B.; Gunal, N.; Pekcan, Z.; Ayva, E. S.; Bozdogan, O.; Gunaydin, S.; Dural, K.
    OBJECTIVES: Re-mediastinoscopy could be risky because of adhesions from the previous mediastinoscopy. The aim of this study was to evaluate the efficacy of a bio-resorbable barrier on adhesion formation in a re-mediastinoscopy rat model. METHODS: Mediastinal dissection similar to mediastinoscopy was done in twenty-eight rats and a polymeric film comprising of polylactic acid and polyethylene glycol (Repel-cv (R), SyntheMed Inc., NJ, USA) was placed on trachea in the study groups. Group 1 (sham, sacrificed at day 30), Group 2 (single barrier, sacrificed at day 30), Group 3 (single barrier, sacrificed at day 60), Group 4(double layer barrier, sacrificed at day 60). Mediastinal adhesions, degree of inflammation, vascular proliferation, foreign body reaction and fibroblast proliferation was compared. RESULTS: Macroscopic dissection showed significantly dense adhesions in Sham Group and Group 3 (p < 0.05). Histopathologic examination showed that there was a significant difference between groups when the foreign body reaction and fibroblast proliferation was evaluated (p<0.05). No significant difference was present between the groups in terms of inflammation and vascular proliferation (p>0.05). CONCLUSIONS: This unique experimental study showed that adhesion barrier was effective as single layer application at day 30 and double layer application at day 60. At clinical conversion, by the application of barrier, the formation of adhesions might be decreased to provide a safe re-mediastinoscopy (Tab. 2, Fig. 4, Ref. 23). Text in PDF www.elis.sk.