Yazar "Saddiqa, Aisha" seçeneğine göre listele

Listeleniyor 1 - 3 / 3
  • Küçük Resim
    Öğe
    Activation of 6-bromoquinoline by nitration: synthesis of morpholinyl and piperazinyl quinolines
    (Arkat Usa Inc, 2018) Çakmak, Osman; Ökten, Salih; Alimli, Dilek; Saddiqa, Aisha; Ersanlı, Cem Cüneyt
    Quinoline forms the key skeletal component of a number of important natural products and pharmacologically-active compounds. Despite a tremendous amount of research pertaining to the derivatization of quinoline, very few general synthetic routes are described in the literature starting from quinoline or tetrahydroquinoline. A simple and convenient method for the polyfunctionalization of quinolines via nitration of bromoquinolines has been developed. This method represents a new synthetic approach to convert brominated nitroquinoline derivatives into useful cyclic amines via nucleophilic-substitution (SNAr) reaction. [GRAPHICS] .
  • [ X ]
    Öğe
    Facile, Expeditious and Cost-effective Preparation of N-Phthaloyl (S)-Amino Acids and Their in silico Activities against Staphylococcus Aureus
    (Taylor & Francis Inc, 2022) Saddiqa, Aisha; Shahzadi, Iram; Usman, Muhammad; Cakmak, Osman; Okten, Salih
    [Abstract No tAvailable]
  • Küçük Resim
    Öğe
    Reinvestigation of bromination of 8-substituted quinolines and synthesis of novel phthalonitriles
    (Acg Publications, 2016) Okten, Salih; Cakmak, Osman; Saddiqa, Aisha; Keskin, Bahadir; Ozdemir, Seda; Inal, Merve
    Bromination of a series of 8-substituted quinolines was reinvestigated and specified for optimum yields and isolation conditions. Mono bromination of 8-hydroxyquinoline (2a) and 8-aminoquinoline (2c) gave mixture of mono and dibromo derivatives 5,7-dibromo-8-hydroxyquinoline (3a), 5,7-dibromo-8aminoquinoline (3c), 7-bromo-8-hydroxyquinoline (3d), 5-bromo-8-aminoquinoline (3e) while 8methoxyquinoline (2b) furnished 5-bromo-8-methoxyquinoline (3f) as sole product. Novel phthalonitriles, 4(quinolin-8-yloxy) phthalonitrile (6) and 4-chloro-5-(quinolin-8-yloxy) phthalonitrile (8) of 8-hydroxyquinoline (2a) were synthesized and converted into their respective bromo derivatives 4-(5-bromoquinolin-8yloxy) phthalonitrile (7) and 4-((5-bromoquinolin-8-yl) oxy)-5-chlorophthalonitrile (9).