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    Hormone replacement therapy and prolactin levels in postmenopausal women
    (1999) Sagsoz N.; Bayram M.; Kamaci M.; Caglayan O.
    Objective: Our purpose was to investigate the effect of hormonal replacement therapy on serum prolactin (PRL) levels in postmenopausal women. Study Design: Hormone replacement therapy (HRT) was initiated to 30 postmenopausal patients. We determined the basal prolactin levels before treatment, and again at the first and third months. We used paired-t and student-t test for statistical analysis. Results: The basal PRL level of menopausal women was 9.6 ± 4.6 ng/ml, while it was 10.5 ± 4.1 ng/ml in premenopausal women (p>0,05). After initiation of HRT, the PRL levels were 9.9 ± 3.3 ng/ml and 10.1 ± 3.9 ng/ml at the first and third months, respectively. These values were not different from basal PRL levels. Conclusion: Serum prolactin determination may be used for the diagnosis of secondary amenorrhea of menopause if clinically indicated. Howover checking the serum prolactin level after the initiation of HRT has no clinical implications.
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    Öğe
    Sigmoid Colon Perforation Mimics a Tuboovarian Absces
    (2018) Sayan C.D.; Yeral M.I.; Ozkan Z.S.; Karaca G.; Asal N.; Aydın O.; Sagsoz N.
    Introduction: An adnexal mass may be diagnosed after a routine pelvic ultrasonographic examination or an emergent hospital admission due to rupture of ectopic pregnancy, adnexal torsion or rupture of tuboovarian abscess. It is necessary to evaluate the origin of the mass initially and to classify patients who need further evaluation and treatment for an urgent condition.Case presentation: We report a case of sigmoid colon rupture due to sigmoid colon adenocarcinoma presenting as acute abdomen with left adnexal mass in a 28 years old woman. Abdominopelvic computed tomography revealed a left adnexal mass with suspicion of tuboovarian abscess. In laparatomy, rupture of sigmoid colon was observed and resection of sigmoid colon was performed. Histological examination of resection part revealed diagnosis of sigmoid colon adenocarcinoma due to familial adenomatous polyposis.Conclusion: This case may be interesting for clinicians because pelvic pain, fever, increased infection markers in the laboratory and mass at ultrasonography or other screening methods could cause a misdiagnosis of tubaovarian abscess especially in reproductive age women. Before the operation of the pelvic mass of all age women with the diagnosis of tuboovarian abscess other causes of the pelvic abscess should come into mine and necessary preparation for operation must be done.
  • Küçük Resim
    Öğe
    What is the protective effect of krill oil on rat ovary against ischemia–reperfusion injury?
    (Blackwell Publishing, 2019) Yeral I.; Sayan C.D.; Karaca G.; Simsek Y.; Sagsoz N.; Ozkan Z.S.; Atasoy P.
    Aim: In this study, we aimed to investigate the protective effect of krill oil (KO) against ischemia–reperfusion (I/R) injury on rat ovary. Methods: This study was conducted with 32 Wistar Albino rats. Rats were divided into four groups, with eight rats in each group-as follows: Sham group, I/R group, I/R + low dose KO group (50 mg) and I/R + high dose KO group (500 mg). The histopathological and follicle counts were performed on the right ovary. The total antioxidant status, total oxidant status and oxidative stress index were evaluated on the left ovary. And also serum N-thiol level, serum T-thiol level, serum disulfide (SDS) level, serum disulfide/N-thiol and serum disulfide/T-thiol ratios were evaluated too. Results: A statistically significant difference was determined between the I/R group and all the other groups for all parameters. There was significant difference between KO groups and the Sham group for the parameters of serum N-thiol, serum T-thiol, SDS, serum disulfide/N-thiol and serum disulfide/T-thiol. SDS, total oxidant status and oxidative stress index were determined to be the highest in the I/R group and the lowest in the low dose KO group. The total antioxidant status values were found to be the highest in the high dose KO group and the lowest in the I/R group. Follicle counts and histological injury scores showed no significant difference between Sham and KO groups. Conclusion: This study demonstrated that KO has beneficial effects on decreasing the injury after I/R on rat ovary. © 2018 Japan Society of Obstetrics and Gynecology