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    INVESTIGATION OF 62 MUSHROOM POISONING CASES APPLIED TO THE EMERGENCY SERVICE DURING ONE MONTH PERIOD
    (Aves, 2008) Deniz, T.; Saygun, M.
    Aim: In this study, it is aimed to investigate the extensive mushroom poisoning cases applied to the Emergency Department during a month. Materials and Methods: The age, gender, the duration of latent phase, clinical and laboratory findings of mushroom poisoning cases were investigated. Results: 62 patients applied to the Emergency Department in total. 51.6% of who were male, 70.9% were in adult age group. When latent phase was investigated, it was seen that the symptoms in most cases (77.3%) appeared within initial 6 hours and in 17.6% of cases after 6 hours. Gastrointestinal symptoms were first existing symptoms in 87.1% cases and there was no significant difference between the age and gender groups in terms of the distribution of these symptoms (p>0.05). Nausea was found in 67.7%, vomiting in 54.8%, stomach-ache in 40.3% and diarrhea in 14.5% of patients. Neurological symptoms such as headache, dizziness and confusion were found in 17.7% of patients, sweating in 1.6% and agitation in 1.6% of patients. Conclusion: Since the latent phase was shorter than 6 hours and no deaths were recorded in adult group in which no enzyme elevation was found, it could be thought that the most mushrooms in the region were not very poisonous; however, this does not indicate that wild mushrooms in this region can be safely consumed.
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    Seroprevalence of tetanus immunity among noninsulin-dependent diabetes mellitus patients
    (Elsevier Science Inc, 2003) Kilic, D.; Kaygusuz, S.; Saygun, M.; Cakman, A.; Uzer, H.; Doganci, L.
    Tetanus is a preventable disease that continues to affect people in both developing and developed countries. The aim of the present study was to evaluate the immunity profile to tetanus in patients with Type II diabetes mellitus (DM) and to compare them with healthy controls. The tetanus antitoxin levels in 310 diabetic patients (104 males and 206 females) and in 200 healthy controls (72 males and 128 females) were measured by ELISA (Virotech, Germany). The mean antitoxin concentration in patient and control groups were 0.8238+/-1.61 and 0.9978+/-1.49 IU/ml, respectively. There was a statistically significant difference between the two groups (z = -3.520, P = .0001 and odds ratio was 2.367). There was a definitive inverse correlation between the duration of diabetes and tetanus antibody titers (Spearman's correlation analysis, r = -.155, P = .006). A gender-dependent difference in the susceptibility to tetanus was present in the diabetic group with antibody titers being significantly higher in males compared with females (z = -2.267, P = .023). For both of control (chi(2) = 20.207, P = .003) and patient (chi(2) = 43.532, P = .0001) groups, there was a significant inverse correlation between the tetanus immunity levels and age. Statistically, a significant drop in antibody titers of both groups was found as the period past from the last immunization increased (Pearson correlation analysis: for patient group r = -.364, P = .0001; for control group r = -.143, P = .044). The tetanus antitoxin levels were significantly increased in individuals who had primary immunization during childhood (for patient group chi(2) = 17.191, P = .0001; for control group chi(2) = 9.911, P = .007). A significant reduction in the level of antitoxin immunity to tetanus in association with an increased susceptibility to infections in patients with diabetes may implicate the need for improving vaccination rates in this patient group. (C) 2003 Elsevier Inc. All rights reserved.