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    Does menopause effect nasal mucociliary clearance time?
    (Springer, 2015) Ozler, Gul Soylu; Akbay, Ercan; Akkoca, Ayse Neslin; Karapinar, Oya Soylu; Simsek, Gokce Ozel
    The aim of this study was to investigate the effect of menopause on nasal mucociliary clearance time by comparing the results of premenopausal and postmenopausal women. A total of 60 women met the criteria and were divided into two groups: premenopausal women (n = 30) and postmenopausal women (n = 30). Nasal mucociliary clearance time of these women was measured and compared. Moreover, the correlation between nasal mucociliary clearance time and menopause duration in postmenopausal women was evaluated. Statistical analysis was performed using the SPSS (Statistical Package for the Social Sciences) 13.0 Evaluation for Windows. Normal distribution of continuous variables was tested with Kolmogorov-Smirnov test. Chi square test was used for comparisons between categorical variables. Kruskal-Wallis test and Mann-Whitney U tests were used for continuous variables when comparing the groups. The statistically significant level was accepted as p value < 0.05. The mean nasal mucociliary clearance time in premenopausal and postmenopausal women was 11.43 +/- A 2.81 (7-16) and 16.76 +/- A 2.73 (12-22), respectively. The mean nasal mucociliary clearance time in postmenopausal women was significantly longer than in premenopausal women (p < 0.0001). Also, there was positive correlation between menopause duration and nasal mucociliary clearance time in postmenopausal women (r = 0.833, p < 0.0001). The clinicians must keep in mind that nasal mucociliary clearance time in postmenopausal women is prolonged and must follow up women in postmenopausal period more closely for respiratory tract diseases, sinonasal and middle ear infections.
  • Küçük Resim
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    The Effect of Passive and Active Smoking on Nasal Mucociliary Clerarance Time
    (Derman Medical Publ, 2016) Ozler, Gul Soylu; Simsek, Gokce Ozel; Akbay, Ercan; Akoglu, Ertap
    Aim: The aim of this study was to investigate the effect of passive and active smoking on NMC by comparing the results of age and sex matched healthy individuals, passive and active smokers. Material and Method: A total of 75 subjects met the criteria and were divided into three groups: control group (nonsmokers, group 1, n = 25), passive smokers group(group 2, n = 25), active smokers group (group 3, n = 25). NMC of these subjects were measured and compared. Moreover, the amount of cigarette consumption of active smokers group were calculated as package to year and the correlation between NMC and the amount of cigarette consumption. in active smokers group were evaluated. Results: The mean NMC in passive smokers group and active smokers group were significantly longer than the control group (p= 0,0001) The comparison of NMC values between the passive smokers group and the active smokers group revealed no statistically significant differences (p >= 0,05). There was positive correlation between the increase in NMC and amount of cigarette consumption in the active smokers group (p= 0,0001, r= 0.433). Discussion: Both active and passive smoking prolonged nasal mucociliary clearance time when they were compared with healthy controls. Tobacco exposure is associated diseases such as asthma, chronic rhinosinusitis, and lower airway infections. It may be related to the direct effect of prolonged NMC.