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    Cognitive evaluation and quality of life assessment in patients with subjective tinnitus (2)
    (Neurological Society R.O.C (Taiwan), 2016) Dağ E.; Bayar Muluk N.; Karabiçak H.; Arikan O.K.; Türkel Y.
    Purpose: To investigate the effects of subjective tinnitus on cognitive functions. Methods: There were 15 patients (10 bilateral, 5 unilateral) with tinnitus who were non-psychiatric in the study group. There were 14 controls (28 ears of them) that were healthy, non-psychiatric and did not have tinnitus. We used questionnaire form; Hospital Anxiety and Depression Scale (HAD); The SF-36 Health Survey; and the Montreal Cognitive Assessment (MoCA) test to evaluate cognitive functions of the subjects. Results: In tinnitus patients, all HAD results (HAD-depression, HAD-anxiety and HAD-total) were insignificantly higher; and all SF-36 items were lower than the control group. In tinnitus group, MoCA scores (mean: 22.28 ± 3.90) were significantly lower then the control group (mean = 26.07 ± 1.74). In tinnitus group, higher MoCA scores were related to increased role limitations due to emotional problems (RE) and physical functioning (PF) values. As subjective tinnitus loudness level (STLL) values increased, HAD-Anxiety values increased and social functioning (SF) values were decreased. In well educated tinnitus patients, MoCA scores found significantly increased. Better Quality of life (QoL) results were found with better MoCA scores. The most important SF-36 items were PF, RE and social functioning (SF). Conclusion: Subjective tinnitus had negative impact not only in quality of life, but also in cognitive function of the patients. © 2016, Neurological Society R.O.C (Taiwan). All rights reserved.
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    How compatible is clinical diagnosis with electrophysiology?
    (Journal of Clinical and Analytical Medicine, 2014) Türkel Y.; Sandikçi U.; Er D.; Yazici T.; Bayrak A.O.; Türker H.Y.
    Aim: The objective of this study was to investigate the correlation of the clinical diagnosis of patients referred to the electroneuromyography laboratory with the electrophysiological diagnosis. Material and Method: Eight hundred eighty two patients were enrolled in the study. Their ages, genders, the clinic that referred the patient, the clinical diagnosis, and the electrophysiological results were registered retrospectively and the results were statistically evaluated. Results: Five hundred twenty four of 882 patients enrolled in the study were women, while 358 of them were men. Four hundred hundred ninety nine (56,6%) of the patients were consulted by the Neurology department, 222 (25,2%) patients were consulted by the Neurosurgery deparment, 59 (6,7%) patients were consulted by the Physical medicine and rehabilitation deparment while 61 (6,9%) patients were referred by the Orthopedy department and 41 (4,6%) by other departments. Carpal tunnel syndrome was the most frequent clinical diagnosis (28,7%). Only in a small group of patients symptoms were assessed rather than the clinical diagnosis (2,9%). In 49,1% of the patients, There was correlation between clinical and electrophysiological diagnosis while 44,7% of patients had normal electroneuromyography results. Discussion: The high rate of the normal electroneuromyography tests and the statistically significant discordance of clinical diagnosis of patients with their electrophysiological test results show that, there are inessential electroneuromyography reguests.
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    Lamotrigine induced seizures in juvenile myoclonic epilepsy
    (2013) Acar B.; Dağ E.; Türkel Y.
    Juvenile myoclonic epilepsy (JME) is a common epileptic syndrome. Before the development of the new antiepileptic drugs (AEDs) after the 1990s, Valproate (VPA) was the first-line treatment in juvenile myoclonic epilepsy. However, the frequent adverse effects and the risk for teratogenicity have resulted in a search for alternative therapies especially in women. Lamotrigine (LTG), topiramate, and levetiracetam, have been used as monotherapy or adjunctive therapy for juvenile myoclonic epilepsy in small patient series. We report a case of a thirty one-years-old female suffered from severe aggravation in myoclonic and generalized tonic-clonic (GTC) seizures after decreasing the lose of VPA and initiating LTG. © 2013 OMU.