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Öğe ADC evaluation of the corticospinal tract in multiple sclerosis(Springer Heidelberg, 2015) Inal, Mikail; Unal, Birsen; Kala, Ibrahim; Turkel, Yakup; Bilgili, Yasemin KaradenizApparent diffusion coefficient (ADC) values derived from diffusion-weighted MR imaging (DWI) provide important information about tissues. The goal of this study was to evaluate the ADC values in the corticospinal tract regions in multiple sclerosis (MS). The ADC values of 42 patients with multiple sclerosis and 46 healthy people were measured. The ADC values in the corticospinal tract at the capsula interna posterior crus from six points and mesencephalon from three points bilaterally in MS patients were compared with those of controls. An ANOVA post hoc test was used to analyse the differences in mean ADC values between the MS and control groups. The mean ADC values of the right (p = 0.008) and left internal capsules (p = 0.000) and right (p = 0.002) and left mesencephalons (p = 0.044) in MS patients were significantly lower than in the control group. There was no significant difference between the right and left side ADC values in MS (p = 0.313 vs. p = 0.223) and control groups (p = 0.756 vs. p = 0.105), respectively. The mean ADC values of the corticospinal tract in MS patients were significantly lower than in the control group. This decreased diffusion may be the result of cellular infiltration due to inflammation, cytotoxic oedema, demyelination or remyelination processes.Öğe Better Visualization of Vermiform Appendix With Tissue Harmonic Imaging Compared to Conventional Sonography(Kowsar Publ, 2014) Inal, Mikail; Unal, Birsen; Bilgili, Yasemin KaradenizBackground: Surgery of appendicitis carries 7-11% negative appendectomy rates. Sonographically visualized normal appendix precludes unnecessary computed tomography (CT) examination and may reduce negative appendectomy rates. Tissue harmonic imaging (THI) has been reported to improve the overall image quality. Objective: We aimed to assess whether THI is more successful than conventional ultrasonography (US) in detecting normal and pathologic appendices. Patients and Methods: The study was performed on 185 patients who applied for routine US examinations in whom clinical findings of appendicitis were detected in 25. We searched for the appendix; applying both THI and conventional US to each patient, one before and the other after the routine US examinations. Patients were divided into two groups; one was evaluated first with conventional US and the other first with THI. When the appendix was found, localization, diameter and time spent for visualization were recorded. Twelve patients were operated; all of whom had appendicitis pathologically. Two methods were compared for: 1. Success rates in all patients; female, male and child groups separately; 2. Visualization of pathologic and normal appendices; 3. Time for visualization of appendix; 4. Comparison of success rates in the adult and child population. The relationship between the rate of visualization and body mass index was evaluated. Results: The appendix was visualized better by THI in all patients, and in the female and male groups (P < 0.001). In children, both methods were more successful compared to adults (P < 0.001, compared to male group, P < 0.001, compared to female group), with no difference between the methods (P = 0.22). When only the normal appendices were concerned, there was significant difference between both methods (P < 0.000). Both methods detected pathologic appendices better than normal ones, with a higher ratio for THI (P = 0.022 for the THI group, and chi(2) = 7.22, P = 0.07 for the conventional US group). THI visualized the appendix faster. Both methods were more successful in lean patients (P = 0.004 for THI, P = 0.001 for conventional US imaging). Conclusions: THI visualizes appendix better than conventional US. It is a simple and time saving method that may eliminate further diagnostic imaging, and it may decrease negative appendectomy rates and related complications.Öğe COLUMN OF BERTIN: NORMAL SONOGRAPHIC FINDINGS(Aves, 2005) Unal, Birsen; Aktas, Aykut; Bilgili, Yasemin; Yilmaz, ErdalIntroduction: We aimed to describe the normal and pathologic sonographic (US) findings of column of Bertin (CB). Materials and Methods: The study was performed on sixty-six patients who had CB on CT. CB was found to be suspicious in 22 cases; with either hypoechoic, heterogeneous, bulging contour, increased vascularity or cystic areas on US. Patient underwent US and CT imaging following their initial CT and US examinations, respectively. On CT images, isodens and homogeneous texture, enhancement equal to renal cortex were accepted as normal findings. The thickness of CB on axial (AT) and longitudinal (LT) sonography images and the thickness of renal parenchyme (PT) on longitudinal images were measured. The ratio of AT to PT and LT to PT were calculated. Echogenity, vascularity, and contours of CB were evaluated on sonography. The data evaluated with Pearson and t tests. Results: CB was bilateral in 39, and double in 9 cases. Totally 136 CB were evaluated. In two sonographically suspicious CB, renal cell carcinoma (pathologically confirmed) and Bosniak type 2 cysts were detected. In LT, AT, LT/PT and AT/PT were 14.0 +/- 3.1 mm (maximum: 23.4mm), 13.2 +/- 2.9 mm (maximum: 21.8 mm), 1.1 +/- 0.19 (maximum: 1.56) and 1.0 +/- 0.17 (maximum: 1.67) in normal cases, 28 mm, 26 mm, 2.15 and 2 mm, in case with renal cell carcinoma. The correlation between thickness of CB and parenchyme was significant (AT-PT r=0.555, p<0.001, and LT-PT r=0.614, p<0.001). Peripheral vascularities were observed in all, central minute vascular focuses in 24 (18%), hypoechogenity in 12 (9.0%), bulging exterior contour in 9 (6%) CB. Conclusion: Increased vascularity, hypoechogenity, increased thickness of CB and thickness to parenchyme ratio are suspicious sonographic findings which may necessitate CT examination.Öğe A Practical MRI Technique for Detecting Abdominal Aorta Aneurysm and Peripheral Arterial Disease(Derman Medical Publ, 2016) Aktas, Aykut Recep; Unal, Birsen; Kara, Simay; Kemal, Gokhan; Yilmaz, Omer; Kayan, Mustafa; Cetin, MeltemAim: Peripheral Arterial Disease(PAD) and abdominal aorta aneurysm(AAA) are frequent problems in geriatric population. In DSA, CTA or MRA techniques contrast agents has to be used for diagnosis that can be nephrotoxic for elderly patients. Magnetic resonans imaging (MRI) is the most powerful, non-ionising radiological diagnostic tool that has the highest soft tissue contrast resolution. The aim of our study was to investigate the effectivity of MRI by the means of detecting the AAA and PAD in comparison with DSA. Material and Method: After getting ethical commitee approvel and informed consent, we have performed Balanced turbo field echo(B-TFE) MRI technique without contrast agent in 1.5 Tesla MRI device before DSA examination. The luminal diameters of renal arteries, infrarenal abdominal aorta, iliac and femoral arteries was measured by using Philips DICOM Viewer R2.2 application. The intraclass corelation coefficient and reliability used to check if the techniques could be used for each other and the t-test was used to measure the differences between them. Results: There has been a high relationship between B-TFE and DSA in detecting the pathologies of larger arteries like aorta. In the case of small arterial pathologies, there is relatively lower relationship between BTFE and DSA. Discussion: For the diagnosis of AAA and PAD, DSA is the gold standart technique but it is invasive and patients have radiation exposure. In the follow up of geriatric patients with larger arterial pathologies B-TFE can be used instead of contrast enhanced MRA and invasive DSA.
