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Öğe Anesthetic Risks Associated With Antley-Bixler Syndrome(Lippincott Williams & Wilkins, 2013) Gencay, Isin; Vargel, Ibrahim; Buyukkocak, Unase; Yazici, Ilker; Apan, AlpaslanAntley-Bixler syndrome is an autosomal recessive disorder characterized by multiple bone and cartilaginous abnormalities. The main features of this syndrome include brachycephaly, midface hypoplasia, dysplasia of ears and nose, radiohumeral synostosis, choanal stenosis, or atresia. Distinctive features are based on craniofacial deformity and humeroradial synostosis. In this report, we describe the anesthesia management of a 20-year-old Antley-Bixler syndrome patient who underwent maxillary advancement via Le Fort I osteotomy. During surgical management of craniofacial syndrome patients, particularly Antley-Bixler syndrome, the whole surgical team should be aware of possible deformities involving the airway, which may be underestimated or nondetected prior to surgery. These deformities including choanal atresia/stenosis may lead to failure of nasotracheal intubation and mask ventilation, therefore jeopardizing the surgical procedure and/or patient safety. Accurate preoperative preparation and being aware of the components of this syndrome is vital to eliminate respiratory complications and enable uneventful anesthetic and surgical management.Öğe A Case of Two Synchronous Cutaneous Collision Tumors(Gazi Univ, Fac Med, 2017) Ayva, Sebnem Kupana; Tepeoglu, Merih; Gunduz, Ozgur; Yazici, Ilker; Bozdogan, OnderCutaneous collision tumors are known as two independent tumors which are close anatomically and separated from one another by well boundaries. We, herein report a 83-year-old female patient with two cutaneous collision tumors in two different localizations at the same time. First cutaneous collision tumor located on left ala nasi was squamous cell carcinoma and basal cell carcinoma and second one located on the right commisure was composed of malignant melanoma (Clark Level IV) and basal cell carcinoma. However, the presence of collision tumors is not uncommon and is often reported in the literature, to the best of our knowledge, it is the first case which shows the association of two synchronous cutaneous collision tumor in the same individual.Öğe COLAGEN MICROANATOMY OF THE HUMAN SEPTUM CARTILAGE(Medknow Publications & Media Pvt Ltd, 2008) Yazici, Ilker; Yavuzer, Reha; Gozil, Rabet; Erdogan, Deniz; Atabay, KenanBy operative observations and cadaver investigations we are describing the collagen microanatomy (tension lines) of the human septal cartilage. Resected parts of 15 patients septums crushed and the form of these materials were observed. Histologic examination was performed on 6 cadavers. Whole quadrangular cartilages excised; dorsal, caudal, basal and central portions sampled as in standart septorhinoplasty procedure, somewhat harvesting a cartilage graft. All were fixed and sliced in sagittal plane, longitudinally; stained with masson trichrome, examinated by a histologist under light microscope. Three of them were examinated by electron microscope but slices were transverse to the axis of cartilage strut or rod. Dorsum and columella posses a longitudinal direction of collagen organisation and strongly packed. Central and base portions have a more disorganised pattern and weaker. Base show collagen organisation perpendicular to palate. These data may be helpful for correction of problematic septum deformities. These lines may also be helpful in septoplasties and understanding the role of septum in maxillofacial development.Öğe Collagen Microarchitecture of the Human Septum Cartilage(Lippincott Williams & Wilkins, 2013) Yazici, Ilker; Yavuzer, Reha; Elmas, Cigdem; Gozil, Rabet; Erdogan, Deniz; Atabay, Kenan…Öğe Dexmedetomidine as an Alternative Anesthetic Agent for Flap Surgery: An Intravital Evaluation in the Cremaster Muscle Flap(Lippincott Williams & Wilkins, 2019) Gencay, Isin; Boybeyi, Ozlem; Unlu, Gulhan; Yazici, Ilker; Aydin, Gulcin; Buyukkocak, UnaseIntroduction: Flap surgery is one of the most commonly used techniques of reconstructive surgery for effective repair of damaged tissue. Optimal anesthetic technique and anesthetic agent plays an important role in flap perfusion. This study aimed to evaluate the effects of dexmedetomidine infusion on the microcirculation in the cremaster muscle flap by direct in vivo monitoring. Materials and Methods: We randomly divided 9 Wistar albino rats into 3 groups. The rats in the control group underwent the surgical procedure (isolation of the cremaster muscle) alone; the rats in the experimental groups 1 and 2 received an infusion of dexmedetomidine (10 and 30 min) after the surgical procedure. Results: The means of vessel diameters, number of functional capillaries, and movements of leukocytes in all groups were evaluated using intravital microscopic examination. The diameters of the arterioles and venules of the cremaster muscle significantly increased in the dexmedetomidine groups. The number of functional capillaries was higher in the dexmedetomidine groups than in the control group. No difference was observed in the movements of leukocytes between the control and experimental groups. Dexmedetomidine significantly increased the diameters of the arterioles and venules of the cremaster flap and the number of functional capillaries. Conclusion: On the basis of the effects of dexmedetomidine on microcirculation, we suggest that dexmedetomidine continue to be used as an anesthetic agent, and may be considered also for reconstructive procedures, particularly flap surgery.Öğe Intravital microscopic evaluation of cremasteric microcirculation in experimental testicular torsion(Elsevier Sci Ltd, 2013) Boybeyi, Ozlem; Yazici, Ilker; Unlu, Gulhan; Aslan, Mustafa Kemal; Soyer, TutkuAim: Although absent cremasteric reflex is a significant clinical finding for testicular torsion (TT), there is limited information about microcirculation of the cremasteric muscle (CM) after TT. This experimental study was performed to evaluate CM microcirculation by intravital microscopy after TT. Materials and methods: Twelve Wistar rats were allocated into two equal groups: control (CG) and torsion (TG). After anesthetization of the CG rats, the CM flap was dissected through a left ventral inguinal incision with its vascular pedicle. In TG rats, TT was performed by rotating left testicles 720 degrees in clockwise direction for 1 h. Then, the CM flap was dissected as in CG, and was placed under an intravital microscope. Vessel diameters, functional capillary perfusion and leukocyte activation in post-capillary venules were measured and evaluated statistically. Results: There was a significant decrease in vessel diameter in TG compared to CG (p < 0.05). The median of perfused capillaries in CG and TG was 13 (11.75-14.30) and 5.5 (4.75-7.25), respectively (p < 0.05). Number of granulocytes (rolling, sticking, transmigrated) was greater in TG than CG (p < 0.05). Conclusion: Intravital microscopic evaluation of CM after TT showed decrease in vessel diameter and number of perfused capillaries, and increase in granulocyte activation. Clinical, electrophysiological alterations in CM after TT can be explained by deterioration of microcirculation of CM. (C) 2013 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved.Öğe Maxilla allograft for transplantation - An anatomical study(Lippincott Williams & Wilkins, 2008) Yazici, Ilker; Cavusoglu, Tarik; Comert, Ayhan; Vargel, Ibrahim; Cavusoglu, Mehtap; Tekdemir, Ibrahim; Siemionow, MariaIntroduction: The aim of this study is to present an anatomic study and a dissection technique to, prepare maxilla graft for transplantation. Methods: Six fixed adult human cadavers were used for dissection of the maxilla grafts. Retrospective reviews of archives of 10 MRI and 5 angiographies of the maxillary region were performed to demonstrate the vascular and soft tissue anatomy of this area. Results: We have harvested maxilla graft as a single unit (larger type of Le Fort II) based on arterial and venous pedicle ready for transplantation. MRI evaluation revealed the vascular structures in the masticatory space and its anterior pterygomaxillary extension. Angiographic observations have demonstrated the arterial blood supply of the maxillary region, which lies within the pterygomaxillary region that we have included in the graft. Conclusions: We are presenting a method for harvesting of the maxilla graft, with vascular supply based on certain anatomic landmarks.Öğe Methylene blue vital staining of nerve stumps in secondary peripheral nerve repair(Elsevier Sci Ltd, 2011) Yazici, Ilker; Kasimcan, Mustafa Omur; Karakaya, Esen Ibrahim; Gurel, Murat; Cavusoglu, Tarik…Öğe Microsurgical training model for lymphaticovenous anastomosis in rat(Wiley-Blackwell, 2012) Yazici, Ilker; Cavusoglu, Tarik; Karakaya, Esen Ibrahim; Comert, Ayhan; Siemionow, Maria…Öğe Reconstruction of Coup de Sabre Deformity (Linear Localized Scleroderma) by Using Galeal Frontalis Muscle Flap and Demineralized Bone Matrix Combination(Lippincott Williams & Wilkins, 2011) Cavusoglu, Tarik; Yazici, Ilker; Vargel, Ibrahim; Karakaya, Esen IbrahimIn this clinical report, we are presenting the combination of demineralized bone matrix combined with bilateral galea frontalis flaps. Based on our 6-month results, this seems to be a reasonable combination to accomplish long-lasting restoration of forehead defects related to en coup de sabre linear localized scleroderma.Öğe Reconstruction of Orbital Floor Fractures Using Autologous Nasal Septal Bone Graft(Lippincott Williams & Wilkins, 2010) Cavusoglu, Tarik; Vargel, Ibrahim; Yazici, Ilker; Cavusoglu, Mehtap; Vural, A. CahitWe describe herein a new technique for reconstruction of the orbital floor, using autologous nasal septal bone and report the Surgical results achieved in maxillofacial trauma patients. Prior to its clinical Surgical application, a cadaver practice was carried Out oil 5 formalin-fixed adult human cadavers to establish the feasibility and efficacy of the method. Fifteen patients with orbital floor fractures, operated between 2005 and 2008, using this technique, were included in the current study. Cadaveric practice revealed that an adequate and appropriate size of septal bone graft can be harvested for reconstruction of the orbital floor. All patients except one had satisfactory clinical and radiologic late results. One patient experienced persistent enophthalmos, possibly due to delayed repair and associated displaced zygomatic boric fracture. Autologous nasal septal bone as an orbital floor bone graft has many advantages, including low donor site morbidity, adequacy and appropriateness of size, and similarity of its bicortical morphology and histologic nature compared with the orbital floor bone. Our clinical results strongly support that this technique call become a satisfactory alternative to existing reconstruction methods.Öğe Second toe-to-thumb transfer with transposition of the thumb stump to second finger(Elsevier Sci Ltd, 2013) Yazici, Ilker; Cavusoglu, Tarik; Karakaya, Esen Ibrahim; Vural, Altughan Cahit; Vargel, Ibrahim…Öğe Use of Triangulation Method in End-to-Side Arterial Microvascular Anastomosis(Lippincott Williams & Wilkins, 2009) Yazici, Ilker; Cavusoglu, Tarik; Comert, Ayhan; Vural, Altughan CahitIn this article, we present the use of triangulation for end-to-si I de microvascular arterial anastomosis. The classic end-to-side anastomosis starts by putting 2 Sutures 180 degrees apart to the lateral arteriotomy aperture that is parallel to the longitudinal axis. We are performing triangulation in end-to-side microvascular artery anastomoses by putting 3 Stay Sutures, securing 2 of them to visualize vascular lumen and reduce the risk of passing suture from the back wall. We have been using this method for the last 5 years and found that triangulation seems to be a safer technique to teach and practice end-to-side microvascular anastomosis.