Yazar "Yildirim, E." seçeneğine göre listele
Listeleniyor 1 - 8 / 8
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Allergic contact dermatitis associated with topical minoxidil: a case report(Wiley-Blackwell, 2015) Yildirim, E.; Baccıoğlu, Ayşe; Kalpaklıoğlu, A. Füsun…Öğe The allergy reality in the pharmacy(Wiley-Blackwell, 2015) Yildirim, E.; Baccioglu, A.; Kalpaklioglu, A. F.…Öğe Assessment of periapical health, quality of root canal filling, and coronal restoration by using cone-beam computed tomography(Medknow Publications & Media Pvt Ltd, 2016) Cakici, E. B.; Yildirim, E.; Cakici, F.; Erdogan, A. S.Aim: The purpose of this study is to use cone-beam computed tomography (CBCT) to describe the prevalence of apical health, the quality of root canal filling, and coronal restorations of endodontically treated teeth in the east Anatolian subpopulation of Turkey. Materials and Methods: CBCT scans were taken from 748 patients attending for the 1(st) time to the clinic at the Oral Diagnosis and Radiology Department at Ataturk University's Faculty of Dentistry in Erzurum, Turkey. All images were analyzed by two research assistants who were trained using examples of CBCT images with and without the presence of periapical radiolucency. The two examiners assessed images from the experiment independently, and the readings were then compared. All data were entered on an MS Excel 2007 spreadsheet and SPSS software 15.0 which was used for statistical analysis. The Chi-square test was used to determine if a patient's periapical status was associated with the technical quality of root filling, coronal status, and to evaluate differences between tooth subgroups. Results: In total, 147 teeth from 748 patients were found to have been treated endodontically. Sixty three teeth were found to have short root canal fillings, whereas 74 teeth had adequate root canal fillings, and the remaining 10 teeth had over extended root canal filling. A significant correlation was observed between the length of root filling and apical periodontitis (P = 0,023). Inadequately dense root canal filling was observed in 141 teeth, whereas adequately dense filling was found in only six teeth. There was a significant correlation between the density of root filling and apical periodontitis (P = 0.044). Coronal restoration was found in 90 teeth, but was not observed in all the three teeth. A crown was present in 54 teeth. There was a significant correlation between coronal restoration and apical periodontitis (P = 0.028). Conclusion: The results indicate that the quality of both the root filling and restoration were found to have impact on the periapical health of root-filled teeth.Öğe The effects of levamisole on oxidative stress induced by copper intoxication in broilers(Taylor & Francis Ltd, 2012) Yigit, A. A.; Cinar, M.; Yildirim, E.AIM: To determine the effects of Cu and levamisole on concentrations of Cu and Fe in plasma and liver, and the effects of levamisole on lipid peroxidation induced by Cu intoxication in broiler chickens. METHODS: In a 2x4 factorial study, 80 one-day-old Ross PM3 broiler chicks were fed diets for 21 days containing either 8 mg/kg Cu (Low Cu) or 250 mg/kg Cu (High Cu) and were treated with 0 (L0), 4 (L4), 8 (L8) or 16 (L16) mg/kg bodyweight levamisole per day from Day 7 of the study, on three consecutive days in their drinking water. This treatment was repeated three times, at 3-day intervals. On Day 21, blood samples were collected from each bird for analysis of concentrations of Cu, Fe and malondialdehyde, and activities of aspartate aminotransferase (AST), alanine aminotransferase (ALT), superoxide dismutase, catalase and glutathione peroxidase (GSH-Px). The birds were killed and liver samples collected for analysis of Cu and Fe. RESULTS: Mean concentrations of Cu and Fe in plasma, and Cu in liver, were increased overall in the High Cu groups compared with the Low Cu groups (p<0.001). Compared with the L0 treatment group on the High Cu diet, treatments L4, L8 and L16 decreased concentrations of Cu in plasma, and L8 and L16 increased concentration of Cu in liver (p<0.05). Mean activities of AST and ALT were increased in untreated birds (L0) fed the High compared with Low Cu diets (p<0.01). In birds receiving the High Cu diet, treatments L4 and L8 decreased activities of AST, and L4 and L16 decreased activity of ALT, compared with L0 (p<0.05). The High Cu diet induced an oxidative stress characterised by increased mean concentrations of malondialdehyde and decreased activities of superoxide dismutase, catalase and GSH-Px (p<0.001). Concentration of malondialdehyde, and activities of superoxide dismutase and catalase were not changed following levamisole treatment in birds on the High Cu diet, and activity of GSH-Px was decreased by the L4 and L8 treatments compared with the L0 group. CONCLUSIONS AND CLINICAL RELEVANCE: The results of the study suggest that treatment with levamisole might alleviate the harmful effects of Cu on the liver, as demonstrated by decreased activities of AST and ALT induced by a diet containing 250 mg/kg Cu.Öğe The effects of magnesium sulphate on the contractile activity of uterus in an animal model of preeclampsia(7847050 Canada Inc, 2014) Yildirim, E.; Macun, H. C.; Cinar, M.; Yigit, A. A.; Ustuner, I.; Aydos, T. R.; Aktuna, Z.Purpose: This study was undertaken to evaluate the effects of magnesium sulfate (MgSO4) on the contractile activity of the uterus in a pregnant rat model of preeclampsia induced by N-nitro-arginine methyl ester (L-NAME). Materials and Methods: Twenty-eight, 160220 gram, three to four month old female Sprague-Dawley rats were used in this study. After conception was confirmed by vaginal smears on the first day of pregnancy, the animals were allocated into four groups according to the chemicals fed in their drinking water as control (nothing administered), L-NAME (50 mg/kg L-NAME), MgSO4 (600 mg/kg MgSO4), and MgSO4 + L-NAME group (600 mg/kg MgSO4 + 50 mg/kg L-NAME). The pregnant uterus strips were isolated on the 19th day and the contractile activity of uterus was examined by applying 0, 0.1, 0.2, 0.4, 0.8, and 2.5 mIU/mloxytocin to each group and responses are recorded accordingly. Results: There were no statistically significant differences regarding fetal parameters and peak amplitudes of the oxytocin stimulated pregnant rat myometrial strips among groups. In L-NAME group at 0 and 0.1 mIU/ml oxytocin, the contraction frequency in a ten-min period was statistically lower than the control group (Z = -2.850, p = 0.004; Z = -2.902, p = 0.004, respectively). In MgSO4 group only at 0 mIU/ml oxytocin, the frequencies of the contractions in ten-min period were statistically lower than the control group (Z = -2.973,p = 0.003). In L-NAME + MgSO4 group at 0, 0.1 and 0.2 mIU/ml oxytocin concentrations the frequencies of the contractions in ten-min period were statistically lower than the control group (Z = -4.018, p = 0.000; Z= -3.23'7,p = 0.001; Z= -2.902, p = 0.004, respectively). In L-NAME + MgSO4 given group at each oxytocin concentrations, the frequencies of the contractions in ten-min period were lower but not statistically different than the L-NAME group. Conclusion: MgSO4 has no significant effect on the amplitude of spontaneous or oxytocin induced myometrial contractions, but decreased the frequency of spontaneous contractions. At each doses of oxytocin, MgSO4 has no significant effect on the frequency of contraction in a pregnant rat model of preeclampsia induced by L-NAME.Öğe Effects of yeast glucomannan on performance, some biochemical parameters and pathological changes in experimental aflatoxicosis in broiler chickens(Ecole Nationale Veterinaire Toulouse, 2011) Yildirim, E.; Yalcinkaya, I.; Kanbur, M.; Cinar, M.; Oruc, E.The study aims to investigate the effects of yeast glucomannan (GM) (Mycosorb (R), Altech) on performance, biochemical parameters and organ pathology in experimental aflatoxicosis in broiler chickens. A total of 120 one day old broiler chickens were assigned to 4 equal groups according to the dietary treatments: whereas the control birds (group C) received the basal diet, those from the group GM were only supplemented with 0.75 g/kg GM, those from the AF group were orally contaminated with 2 mg/kg total aflatoxins and those from the GM + AF group were exposed to aflatoxins and supplemented with GM for 21 days. Growth performance (body weights, weight gains). feed intake and feed efficiency were weekly assessed on all birds and at the end of the experiment, plasma biochemical parameters, visceral organ masses and conventional histopathology of liver and kidney were determined in 9 birds from each experimental group. The dietary aflatoxin contamination has significantly altered the growth performance (significant decreases in the final weight and in weight gains for the 3(rd) week and for the whole period), the feed intake mainly in the last week and the food efficiency, induced severe degenerative and necrotic lesions coupled to fibrosis in liver and kidney leading to significant changes in total plasma protein, total cholesterol, urea, creatinine and calcium concentrations, as well as in the AST (aspartate aminotransferase) and GGT (earnmaglutamyl transferase) activities. Nevertheless, the weight gains and feed efficiency were partially restored and the uraemia, the creatininemia and the plasma AST activity were significantly improved when aflatoxin contaminated birds were supplemented with GM despite the presence of liver and kidney damage similar to those observed in the AF group. These results demonstrate that a short duration (21 days) period is sufficient for inducing aflatoxicosis in broilers and that the yeast glucomannan supplementation at the dose of 0.75 g/kg may partially alleviated the deleterious effects but was insufficient for preventing tissue damage.Öğe Relationship between food sensitization and serum leptin levels with local airway inflammation in allergic rhinitis(Wiley-Blackwell, 2015) Kalpaklioglu, A. F.; Baccioglu, A.; Yildirim, E.; Kisa, U.…Öğe The Effect of Dietary Garlic (Allium Sativum), Black Cumin (Nigella Sativa) and Their Combination on Performance, Intestine Morphometry, Serum Biochemistry and Antioxidant Status of Broiler Chickens(Facta-Fundacio Arnco Ciencia Tecnologia Avicolas, 2020) Aydogan, I; Yildirim, E.; Kurum, A.; Bolat, D.; Cinar, M.; Basalan, M.; Yigit, A.This study was conducted to examine the effects of garlic (G), black cumin (BC) and G+BC within the broiler rations, on performance, relative organ weights, intestinal morphology, serum biochemistry and plasma total oxidant/ antioxidant status. Two hundred broilers chicks (Ross 308) were used and they were divided into 4 groups consisting of 5 subgroups of 10 animals each. The trial was ended on the 35th day. No addition was made to the control group ration. 5g / kg garlic (G), 5g / kg black cumin (BC) and 5g / kg G + 5g / kg BC were added to the experimental group rations, respectively. There was no statistical difference among the trial groups in terms of BWG, FI, FCR and relative organ weights (p>0.05). Serum total protein (p<0.05) and albumin (p<0.001) levels were higher in BC and BC +G groups as compared to G and control group. Serum AST activity were lower in G group as compared to control and other experimental groups (p<0.05). On histological examinations, regarding the duodenal epithelium; there was no difference among the trial groups. Hyperemia was observed, especially in the G group, in macroscopic exams of lamina propria and other viticular areas. The lymph follicles were more wide spread in the G + BC, G and BC groups than in the control. The results of the study showed that the combination of BC and G can have beneficial effects, and different doses of G and BC may be used to see positive or negative effects.
