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    Helicobacter pylori seropositivity and atherosclerosis risk factors
    (Karger, 2004) Köksal, A.; Ekmekci, Y.; Karadeniz, Y.; Köklü, S.; Apan, T.; Yilmaz, M.; Yildiz, A.
    Certain viral and bacterial infections may contribute to the initiation and progression of atherosclerosis. The aim of this study is to determine whether Helicobacter pylori ( HP) seropositivity contributes to conventional atherosclerosis risk factors in the development of an early sign of atherosclerosis: intima-media thickness (IMT) of the carotid artery. Eighty-four patients who had at least two conventional atherosclerosis risk factors and a control group of 50 patients having no risk factors for atherosclerosis were enrolled in the study. None of the patients had ever received HP eradication treatment. HP IgG antibodies were determined by enzyme-linked immunosorbent assay. Carotid artery IMT was measured 1 cm before the carotid bifurcation. Seventy-five percent of the study group was HP seropositive. HP seropositive ( n = 64) and seronegative ( n = 21) groups were identical in terms of sex distribution, smoking pattern, mean age, hemoglobin, leukocyte, platelet, C-reactive protein, erythrocyte sedimentation rate, glucose, cholesterol, triglyceride, low-density lipoprotein, high-density lipoprotein, systolic blood pressure and diastolic blood pressure levels. There was no significant difference between the mean carotid IMT of HP seropositive (0.8 +/- 0.3 mm) and negative ( 0.8 +/- 8 0.3 mm) patients in the study group. Similar to the study group, there was no statistically significant difference between mean carotid IMT of HP seropositive (0.56 +/- 0.19 mm) and negative patients (0.67 +/- 0.13 mm) in the control group ( p = 0.2). Future studies concerning virulent strains are needed to determine the probable role of HP in atherosclerosis. Copyright (C) 2004 S. Karger AG, Basel.
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    Ovarian wedge resection by minilaparatomy in infertile patients with polycystic ovarian syndrome: a new technique
    (Elsevier Sci Ireland Ltd, 2003) Yildirim, M.; Noyan, V.; Tiras, M.B.; Yildiz, A.; Guner, H.
    Objective: To determine the effects of ovarian wedge resection by minilaparotomy in infertile patients with polycystic ovarian syndrome (PCOS). Study design: One hundred and thirty-four anovulatory patients with PCOS, who were previously treated with clomiphene citrate and gonadotropins and did not concieve were operated via minilaparotomy with microsurgical principles and ovarian wedge resection was performed on each subject. Pregnancy rates and adhesion formation were investigated retrospectively. Results: A total of 121 pregnancies were achieved in 2 years (90%). One hundred and four patients concieved within the first 6 months (78%) and the remaining 17 patients concieved within 2 years (13%) following the operation. Sixty-eight patients had a second pregnancy later. In the post-operative period, 24 patients had cesarean delivery and 20 had diagnostic laparoscopy. Out of these 44 patients, only 5 of them were found to have minimal adhesions. Conclusion: This technique offers high pregnancy rates and minimal adhesion formation. Ovarian wedge resection by minilaparotomy might be an alternative treatment approach in patients with PCOS who did not concieve with standart ovulation induction protocols. (C) 2002 Published by Elsevier Science Ireland Ltd.