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    Design and Experimental Verification of a Posture Correction System: Development of an Artificial Neural Network to Predict the Effectiveness of the Developed System to Correct Poor Posture
    (Taylor & Francis Inc, 2024) Yildiz, Eren; Das, Memik
    This research aims to address designing an experiment to evaluate the impact of a developed posture correction system. Also, the correct posture learning habits of users can be estimated with an artificial neural network (ANN) structure that predicts the poor posture count (PPC) in the last session of the experiment using the information received from the users and the developed system. The developed system aims to collect data from different individuals about their sitting posture information. An ANN analysis tool is developed to predict the individuals' habits of learning the correct posture. This setup is based on a flex sensor and has the capability of collecting posture information data and warning the user when the posture is not correct. A three-session experiment was conducted on 12 healthy participants to investigate his/her posture habits. The data was analyzed to determine the average PPC value. It was observed that PPC decreased by 56.27% from session one to session three, and the average improvement evaluation (IE) value after each session was found to be positive. In addition to experimental analysis, the collected posture data was used to train and validate an ANN architecture capable of predicting PPC values. The developed device is effective in improving posture habits and has the potential to predict PPC values with the ANN architecture.
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    Urinary excretion of heat-shock protein 70 in patients with familial mediterranean fever
    (Bayrakol Medical Publisher, 2022) Yildiz, Eren; Gokceoglu, Arife Uslu; Badem, Nermin Dindar; Alioglu, Bulent
    Aim: In this study, we aimed to determine the urinary excretion of HSP70 in patients with familial Mediterranean fever (FMF). Material and Methods: Children with FMF attack-free period and FMF attack and healthy controls were enrolled in the study. Characteristics of patients and laboratory results were recorded. Urine HSP70 levels, urine creatinine were studied, and urinary excretion of HSP70 was calculated. Results: Mean levels of urine HSP70 in patients with FMF attack-free period were significantly lower than that of controls (p = 0.01). The mean urinary excretion of HSP70 was higher in patients with an FMF attack than that of patients with FMF attack free period, but similar with controls. The mean HSP70 and urinary excretion of HSP70 were not different in children with homozygous MEFV mutation, in children with M694V mutation and others (p > 0.05). There was negative correlation between urinary excretion of HSP70 and the age of patients and controls (r =-0.284, p < 0.01). There was no statistically significant correlation between urinary excretion of HSP70 and leukocyte counts, CRP, ESR, fibrinogen levels (p > 0.05). Discussion: Urinary excretion of HSP70 increased in FMF patients during the attack period as it is a stress factor. Lower levels of urinary excretion of HSP70 in FMF patients with attack-free period may be related to the anti-inflammatory activity of colchicine. Urinary excretion of HSP70 was negatively correlated with the age of pediatric patients. MEFV mutation type as homozygous mutation and M694V mutation did not affect levels of urinary excretion of HSP70.