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Öğe Gold-nanoisland-decorated titanium nanorod arrays fabricated by thermal dewetting approach(Ice Publishing, 2019) Dinc, Dilek Ozden; Yilmaz, Mehmet; Cetin, Saime Sebnem; Turk, Mustafa; Piskin, ErhanSolid-state dewetting is a simple and versatile technique for fabricating plasmonic-nanostructure-decorated platforms. However, understanding of the optical properties of these platforms and the effect of the three-dimensional (3D) morphology of the underlying substrate on the dewetting of metallic thin films is still needed for developing effective platforms for further applications. Herein, the authors report gold (Au)-nanoisland-decorated 3D titanium dioxide (TiO2) nanorod (TiNR) arrays fabricated through the thermal dewetting approach. It is demonstrated that the plasmonic behavior of the fabricated platforms can be manipulated by controlling both the initial gold film thickness and annealing temperature. Furthermore, the fabricated platforms exhibited Raman signal enhancement of up to similar to 10(2) for the probe molecule methylene blue. The surface characteristics of the fabricated platforms were evaluated for biological interactions. For this purpose, osteogenic cells (Saos-2) were seeded on the samples. It was found that the cell behavior was improved on the anisotropic micro-nano pattern of TiNRs and gold-coated TiNR films because of features such as topography and surface chemistry. The authors' results clearly offer simple but important guidance for the creation of surface-enhanced Raman spectroscopy platforms and tissue-integration devices as biomaterials for real-life applications.Öğe Neurovascular anatomy of pronator quadratus for reanimation of blepharoptosis(Springer France, 2022) Igde, Murat; Yilmaz, Mehmet; Gungor, Yigit; Saglam, Murat Enes; Salman, Necati; Tapan, Mehmet; Comert, ElaPurpose Pronator quadratus (PQ) is a quadrilateral muscle on a volar distal side of the forearm. The purpose of this study was to establish a novel surgical technique for reanimation of the upper eyelid for severe ptosis using PQ functional free muscle flap. Methods The current study is a cadaveric study, designed to assess a PQ free flap transfer that lies between the frontalis muscle and the upper eyelid. Fourteen PQ from fourteen embalmed cadavers were dissected, and their neurovascular pedicles were isolated. Then they were transferred to the area on the contralateral side between the frontalis muscle and upper eyelid tarsal cartilage. Measurements of the PQ flap, antebrachial region, orbitofrontal region, recipient vessels, and motor nerve were performed using a caliper. The extendibility of neurovascular pedicles was evaluated by measurements of lengths. In addition, the diameter of PQ flap vascular pedicle vessels was compared with recipient vessels. Results The mean width of the proximal border of PQ was 41.92 +/- 2.05 mm and the distal border of the PQ was 42.84 +/- 4.04 mm. The mean PQ artery (type II, Mathes-Nahai flap classification) length was found to be 117.72 +/- 7.77 mm. The mean diameter of the anterior interosseous nerve was 1.89 +/- 0.08 mm. The mean diameter of the uppermost branch of the frontal branch of the facial nerve was 1.18 +/- 0.25 mm. The length and diameter of neurovascular pedicles of muscle flaps were adequate for microvascular anastomoses and neurorrhaphy. Conclusions The results of this anatomical study demonstrate that the PQ free flap transfer has anatomical features that are suitable and compatible with the surgical treatment of blepharoptosis.Öğe Pronator quadratus musculo-osseous free flap for wide hard palatal defect reconstruction: An anatomical study(Elsevier Sci Ltd, 2023) Igde, Murat; Salman, Necati; Gungor, Yigit; Yilmaz, Mehmet; Comert, Ela; Saglam, Murat Enes; Baykara, YigitWide hard palate defects include congenital and acquired defects that are six square centimeters or larger in size. Obturator prostheses and autologous soft tissue transfers have been used to reconstruct palatal defects. This study aims to repair wide, hard palatal defects by using a pronator quadratus musculo-osseous free flap to achieve subtotal reconstruction. Seventeen formalin-fixed cadavers were dissected. Free musculo-osseous pronator quadratus flaps were prepared after a 12 cm curvilinear volar skin incision. Standard 30 x 23 mm (690 & PLUSMN; 52.12 mm2) hard palate defects were made by chisels and saws. A subcutaneous tunnel was created between the mandibular edge cross point of the facial vessels and the retromolar trigone through the subcutaneous to the superficial musculoaponeurotic system by dissection. Area measurements of the pedicle and palate defects were performed by the ImageJ program (National Institutes of Health, Bethesda, MD, USA) on drawings over an acetate layer of materials. Mandibular distances of gonion-facial vessel cross point (a), goniongnathion (m), and facial vessels' cross point-retromolar entrance point (h) were measured. Ratios of h/m and a/m were calculated. The mean pronator quadratus area was 2349.39 & PLUSMN; 444.05 mm2, and the arterial pedicle pronator quadratus diameter was 2.32 & PLUSMN; 0.34 mm. The mean pedicle length of the pronator quadratus was 117.13 & PLUSMN; 8.10 mm. Study results showed that musculo-osseous pronator quadratus flaps' bone and muscle parts perfectly fit on the defects in all cadavers. Pronator quadratus musculo-osseous flap is a feasible surgical option for wide, hard palatal defect reconstruction strategies.& COPY; 2023 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.