Yazar "Yilmaz A." seçeneğine göre listele

Listeleniyor 1 - 2 / 2
  • [ X ]
    Öğe
    Prognostic significance of caspase- 3, Bcl-2, P53 and GSTPI expressions in lung adenocarcinoma
    (Society of Pharmaceutical Sciences of Ankara (FABAD), 2013) Oguztuzun S.; Oguz Ada A.; Kilic M.; Cakir E.; Yilmaz A.
    Lung adenocarcinoma is one of the most fatal cancers in humans, and many factors are known to contribute to its poor prognosis. The aim of this work is to investigate the prognostic value of the apoptosis-regulating markers (caspase-3, bcl-2, p53) and the important detoxification enzyme (GST pi), and analyze the relationships among these immunohistochemical (IHC) results, patients' clinical characteristics, and survival. IHC stainings were performed on 89 lung adenocarcinoma specimens obtained from 89 patients from the Atatürk Chest Diseases and Thoracic Surgery Training and Research Hospital, Ankara, Turkey. The medical records of the patients were reviewed retrospectively. The correlation between the presence of protein expression and clinicopathological parameters (gender, age, tumor stage and histology) was examined by using the Pearson correlation test. Survival analysis was carried out by the Kaplan-Meier method. The prevalence of caspase 3, bcl-2, p53, and GST pi expression was 48%, 57%, 95% and 52%, respectively. The expression rate of p53 was relatively high in smokers than that in non-smokers. There were no correlations among the immunoreactivities of bcl- 2 and GST pi in clinical stage, and overall survival. However, there was a significant relationship between caspase-3 and p53 expressions and overall survival. Caspase-3 expression was correlated with good prognosis, and p53 expression was correlated with poor prognosis.
  • [ X ]
    Öğe
    Sports in children's picture books
    (Horizon Research Publishing, 2019) Yilmaz A.; Pala Ş.
    From an early age, it is very important to encourage children to enjoy sports and to make sports. The awareness and habits gained in the early years of life affect life in the following years. Illustrated children's books are important for early childhood children to gain interest, curiosity and awareness towards an area. Sports and sports-specific elements are among the habits that should be given to children at a young age. The aim of this study is to determine the sport elements in the children's books. For this purpose, the research was designed with a case study pattern of qualitative research approaches. Criterion sampling technique was used in the study. Thirty books with 3-6 years old child development characteristics and the subject of which are direct sports are included in the study group. Document analysis technique was used in data analysis. In the research, it has been determined that books related to different sports branches, sports materials are depicted, sports-specific concepts are mentioned and technical and tactical information is presented. In the sections where sporting competitions take place, are depicted such as fairness / fair competition, fairness, benevolence and ability to tolerate winning-loss values. The processing of sports in illustrated children's books will be effective in the positive attitudes of children in this age of development towards sports. © 2019 by authors, all rights reserved.