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Öğe Smile Attractiveness: Differences among the Perceptions of Dental Professionals and Laypersons(2017) Öz, Abdullah Alper; Akdeniz, Berat Serdar; Canlı, Erman; Çelik, SametObjective: The aim of this study was to analyze the acceptable values of female and male smile attractiveness based on different amounts of gingival display and buccal corridor widths, as judged by dental professionals and laypersons. Methods: The frontal smile photographs of a male and female model were modified to create seven different smile photographs of the same individual with different amounts of gingival display and buccal corridor widths. Overall, 249 evaluators in four groups (Group 1=orthodontists, Group 2=prosthodontists, Group 3=oral surgeons, and Group 4=laypersons) evaluated 28 images of different smiles with a visual analogue scale. Significant statistical differences were found among the evaluator's scores (p<0.05).Results: For female smiles, the highest scores were obtained for 12% and 0% buccal corridor width. For male smiles, the highest scores were obtained for 4%, 0%, 12%, and 16% buccal corridor width for Groups 1, 2, 3, and 4 respectively. The highest scores were obtained for +2 mm and -3 mm of gingival display for female smiles. Conclusion: The amount of gingival display, the buccal corridor width, and the knowledge in the field affects the perceptions of smile attractiveness. Thus, 3 mm of gingival display and buccal corridor width larger than 16% should be avoided for esthetic reasons during dental treatment.Öğe Effect of body mass index percentile on skeletal maturation of cervical vertebrae and hand-wrist and dental maturation(TAYLOR & FRANCIS LTD, 2020) Erhamza, Turkan Sezen; Kilicaslan, Yagmur; Unver, Fatma NazikObjective: The aim of this study was to evaluate the relationship between age- and gender-specific body mass index (BMI) percentile and skeletal and dental maturation in Turkish adolescents. Materials and methods: A sample of 429 patients (171 males, 258 females aged between 7 and 17 years) was selected. Skeletal maturation was identified in the hand-wrist radiography by Bjork, Grave and Brown (BGB), and the cervical vertebrae maturation (CVM) method defined by Hassel and Farman in lateral cephalometric radiography. Dental maturation was determined by the Demirjian method. BMI was calculated by reference curves used for Turkish children. A regression model was used for the relationship between BMI percentile and skeletal and dental maturation. Results: There was no significant correlation between BMI and skeletal maturation of cervical vertebrae and dental maturation. A one-percentile increase in BMI percentile accelerates the increase of period (likelihood of being post-pubertal period) to 1.016 times (p < .05). Skeletal maturation of hand-wrist and cervical vertebrae and dental maturation were more prominent in females compared to males (p < .05). Males and females were not statistically significantly different in BMI percentile (p = .52). Conclusions: BMI may be considered before deciding to estimate the skeletal and dental maturation in an individual by the relevant methods.Öğe The evaluation of the relationship between cervical vertebral anomalies with skeletal malocclusion types and upper airway dimensions(TAYLOR & FRANCIS LTD, 2020) Adisen, Sirin Rabia; Adisen, Mehmet Zahit; Ozdiler, Ferabi ErhanObjectives: To compare the prevalence of cervical vertebral anomalies (CVAs) in different skeletal malocclusions and to evaluate the relationship between upper airway dimension and vertebral anomalies. Methods: A retrospective study was performed on lateral cephalometric radiographs of 2062 patients aged 7-49 years. Skeletal malocclusion type, presence of CVAs, and upper airway area of 1856 patients who met the inclusion criteria of the study were recorded. The obtained data were transferred to the SPSS program for statistical analysis. Results: The mean age of the patients was 13.8 +/- 3.7 years. The prevalence of CVAs was 45.7%. There was no significant difference in prevalence between skeletal malocclusions (p = 0.89). According to airway measurements, no significant difference was found between patients with and without CVAs (p = 0.718). Conclusion: The present results suggest that there is no direct effect of skeletal malocclusion type and upper airway dimension in the etiology of CVAs.Öğe Assessment of soft tissue changes after LeFort I advancement(SPRINGER, 2021) Akan, Burcin; Gokce, Gokcenur; Unal, Beyza Karadede; Erhamza, Turkan SezenPurpose The aim of this retrospective study was to investigate the soft tissue changes after maxillary advancement in class III patients. Methods Pre- and post-operative lateral cephalometric radiographs of 20 patients treated with maxillary advancement surgery were included in our study. Skeletal, dental and soft tissue measurements were performed by a single researcher using Dolphin Imaging software version 11.95 (Dolphin Imaging, Chatsworth, CA, USA). Pairedttest was used for statistical evaluation andp < 0.05 was considered statistically significant. Results The amount of motion in soft tissues, respectively, are UL-E: 2.05 mm, ST.A: 0.65 mm, ST.B: - 5 mm, ST.Pog: - 5.73 mm, ST.Conv: - 3.95 mm, nasal prominence: - 1.58 mm, nasal height: 2.76 mm and upper lip length: 2.22 mm. The change of distance to horizontal and vertical reference planes are, respectively, Prn-HRL: 3.02 mm Prn-VRL: 1.76 mm Sn-HRL: 2.76 mm Sn-VRL: 2.94 mm ST.A-HRL: 3.74 mm ST.A-VRL: 3.81 mm UL-HL: 3.93 mm UL-VRL: 4.57 mm LL-HRL: 2.29 mm LL-VRL: 5.31 mm. Conclusions It can be concluded that soft tissues related to maxilla moved anteriorly due to maxillary advancement.Öğe Identification of Maxillofacial Problems in Extraoral Photographs by Panel Members: A Pilot Study(Aves, 2019) Kilicaslan, Yagmur; Erhamza, Turkan Sezen; Ozdiler, Ferabi ErhanObjective: The aim of this pilot study was to evaluate the effectiveness of the profile and frontal photographs in determining sagittal maxillofacial problems by the panel members created from different professional groups. Methods: Frontal and profile photographs of four individuals with skeletal Class I, Class II Division 1, Class II Division 2, and Class III malocclusion were assessed by panel members. A total of 42 panel members from 7 different professions participated in the study. Panel members were asked to choose one of the frontal or profile photographs to be used in determining the maxillofacial problem. Mann-Whitney U test, Kruskal-Wallis test, and Fisher's exact test were applied to evaluate the difference between the panelists. Results: Of the 42 panel members, 16% selected frontal photographs, and 84% selected profile photographs. There were no statistically significant differences between seven panels with regard to photography selection (p>0.05). When all panel members were compared with regard to gender, 17.9% of the frontal photographs and 82.1% of the profile photographs were selected by females, whereas 15.4% of the frontal photographs and 84.6% of the profile photographs were chosen by males. There was no statistically significant difference between males and females (p>0.05). Conclusion: It was found that the profile photograph was more preferred and informative in determining the sagittal maxillofacial problem.Öğe Effect of rapid maxillary expansion on halitosis(Mosby-Elsevier, 2018) Erhamza, Turkan Sezen; Ozdiler, Ferabi ErhanIntroduction: The objective of this study was to evaluate the effect of rapid maxillary expansion (RME) on halitosis. Methods: Thirty children (11-15 years old) were randomly divided into RME and control groups. The RME group consisted of 15 children treated with hyrax appliances, and the control group included 15 children without treatment. Halitosis was evaluated with the halimeter and the organoleptic method. Plaque index and gingival index scores were recorded. Acoustic rhinometry was used to measure the nasal volume. Measurements were obtained at 2 times: before RME, and after retention at 4 months. The Wilcoxon signed rank test and the paired t test were used for intragroup comparisons, and the Mann-Whitney U test and the Student t test were used for intergroup comparisons. Results: Halitosis (halimeter and organoleptic values) decreased significantly in the RME group (P <0.001). Insignificant changes of halitosis were observed in the control group. Intragroup and intergroup comparisons showed no statistically significant differences for the plaque index. Gingival index values were significantly decreased with RME (P < 0.05). Nasal cavity volume increased significantly in the RME group (P <0.01). Conclusion: RME was shown to lower halitosis values. RME could be a treatment option for patients with maxillary transverse deficiency and halitosis.Öğe Effects of impacted maxillary canines on root resorption of lateral incisors(Urban & Vogel, 2017) Ucar, Faruk I.; Celebi, Ahmet A.; Tan, Enes; Topcuoglu, Tolga; Sekerci, Ahmet ErcanThe aim of this study was to analyze the amount of root resorption of maxillary lateral incisors by relating the position, location, and angulation of the impacted canine using cone-beam computed tomography (CBCT). The study sample consisted of panoramic and CBCT radiographs of 46 patients with a unilateral impacted canine (16 males and 30 females; mean age: 19.53 +/- 6.66 and 19.44 +/- 5.77 years, respectively). Sector location and canine angulation were measured in panoramics. All tomographs were obtained using CBCT (NewTom 5G, QR, Verona, Italy) and three-dimensional (3D) reconstructions of the maxillary laterals assessed by Mimics 14.01 image analysis software. Upper lateral incisor volume was smaller on the impacted side (401.95 +/- 83.69 mm(3)) than on the nonimpacted side (433.54 +/- 92.6 mm(3), P < 0.05). There were no significant differences of lateral root resorption volume when comparing the impacted canines being on the labial or palatal sides (P > 0.05), but impacted canine angulation was significantly steeper on the labial side (70.85A degrees) than on the palatal side (46.09A degrees, P < 0.05). The volume of root resorption of laterals when comparing the various positions of the canine in different sectors or canine angulation in 30(o) intervals was not statistically significantly different (P > 0.05). The impacted canines caused root resorption of lateral incisors. The angulation of the canine was steeper on the labial side than on the palatal side but root resorption of adjacent laterals was not different. There were no statistically significant differences in the amount of root resorption of the laterals when the canine was evaluated according to localization and angulation.Öğe Evaluation of black spaces between maxillary central incisors by dentistry students and laypeople(Nihon Univ, School Dentistry, 2017) Ayyildiz, Erdem; Tan, Enes; Keklik, Hakan; Celebi, Ahmet A.; Pithon, Matheus M.This study aimed to compare the perception of smile esthetics and alterations among dentistry degree students and laypeople to identify differences in the esthetic perception of black spaces between the maxillary central incisors among Turkish laypeople and students in different study years. Photographs altered to include black spaces of various sizes at the midline were evaluated by 208 dentistry students in years 1-5 and 45 Turkish laypeople. Perceptional differences in different photographs were statistically significant. The students in years 2-5 were more aware of differences between photographs than year 1 students and laypeople. The proportion of participants who decided the most attractive photograph as A was highest among 3rd year students, followed by 5th year students. However, the proportion of students agreeing on the least attractive image was highest among 4th year students, followed by 3rd year students. Photographs A and H were selected as the most and least attractive, respectively, by all participants. The esthetic perception of 1st and 2nd year dentistry students was very different from that of laypeople. To increase esthetic perception among dentistry students, specific lessons with clinical photography should be included in dental education.Öğe Effects of cleft lip and palate on the development of permanent upper central incisors: a cone-beam computed tomography study(Oxford Univ Press, 2015) Celebi, Ahmet A.; Ucar, Faruk I.; Sekerci, Ahmet E.; Caglaroglu, Murat; Tan, EnesObjective: The aim of this study was to evaluate 1. the differences among the cleft sides of unilateral cleft lip and palate (UCLP) patients, non-cleft sides of the same UCLP patients and well matched control patients in the root development and position of permanent upper central incisors and 2. possible gender differences. Materials and methods: The study sample consisted of 40 patient (20 males and 20 females; mean age: 14.84 +/- 3.2 years) with non-syndromic UCLP patients, and 40 control patients (20 males and 20 females; mean age: 13.38 +/- 1.6 years). Cone-beam computed tomography (CBCT) images were taken off from all patients. All tomographs were obtained in supine position by using CBCT (NewTom 5G, QR, Verona, Italy). Results: Significant smaller root volume of central incisor was observed on the cleft side than on the non-cleft side of UCLP patients (P < 0.05). No significant difference in the root development and position of the central incisors was found between the non-cleft side of the UCLP and the control group (P > 0.05). There were no statistically significant gender differences in any linear, angular, or volumetric measurements (P > 0.05). Only the root volume of the cleft side was smaller in females than in males (P < 0.05). Conclusions: In general, root volumes of central incisors on the cleft side were 12.15 per cent smaller than non-cleft side. Root development of the central incisor was much more influenced by the cleft in females than in males.Öğe The distribution of cervical vertebrae anomalies among dental malocclusions(Wolters Kluwer Medknow Publications, 2015) Kamak, Hasan; Yildirim, ErenAims: The aims of our study were to investigate the distribution of cervical vertebrae anomalies (CVAs) among dental Angle Class I, II, and III malocclusions in Turkish population and whether a correlation between CVA and dental malocclusion. Materials and Methods: The study was performed on lateral cephalometric radiographs which were taken at the Department of Orthodontics, Faculty of Dentistry, Kirikkale University. The final sample of 318 orthodontic patients was included in the study. Dental malocclusions were performed according to Angle classification. CVAs were categorized: (1) fusion and (2) posterior arch deficiency (PAD). The Chi-square test was used to the analysis of the potential differences among dental malocclusions. Results: The final sample of 318 patients was examined. CVA was observed in 42 individuals (of 26 [8.17%] had fusion and 16 [5.03%] had PAD), with a frequency of 13.2%. Of the 26 fusion defect, 8 (30.7%) had Angle Class I, 8 (30.7%) had Angle Class II, and 10 (38.4%) had Angle Class III malocclusion. Of the 16 PAD, 8 (50%) had Angle Class I, 8 (50%) had Angle Class II but no patients with Angle Class III malocclusion was observed. The distribution of dental malocclusions regarding CVA was not statistically significant (P = 0.076). Of these 42 individuals with CVA, 52.3% (15 fusions and 7 PAD) were females and 47.7% (11 fusions and 9 PAD) were males. Conclusion: In our study, the prevalence of fusion and PAD were found 8.1% and 5.0% in Turkish population, respectively. Besides, no statistically significant correlation between CVA and Angle Class I, II, and III malocclusions were found. Our findings support the studies showing no gender dimorphism.Öğe Comparison of Soft Tissue Cephalometric Norms between Turkish and European-American Adults(Hindawi Ltd, 2013) Celebi, Ahmet Arif; Tan, Enes; Gelgor, Ibrahim Erhan; Colak, Tugba; Ayyildiz, ErdemOne of the most important components of orthodontic diagnosis and treatment planning is the evaluation of the patient's soft tissue profile. The main purpose of this study was to develop soft-tissue cephalometric standards for Turkish men and women and compare them with the cephalometric standards of normal European-American white people. The sample included 96 Turkish adults (48 women, 48 men), aged 20 to 27 years. Turkish subjects have increased facial convexity associated with retruded mandible, more obtuse lower face-throat angle, increased nasolabial angle and upper lip protrusion, deeper mentolabial sulcus, and smaller interlabial gap compared with European-American white people. It is appropriate to consider these differences during routine diagnosis and treatment planning of a Turkish patient or an American patient of European ancestry. Turkish males reveal more obtuse mandibular prognathism and upper lip protrusion, and smaller nasolabial angle than females.Öğe Effect of ovarian activity on orthodontic tooth movement and gingival crevicular fluid levels of interleukin-1 beta and prostaglandin E-2 in cats(E H Angle Education Research Foundation, Inc, 2013) Celebi, Ahmet Arif; Demirer, Serhat; Catalbas, Bulent; Arikan, SevketObjective: To evaluate whether there is any correlation between ovarian activity and two potent bone-resorbing mediators (prostaglandin E-2 [PGE(2)], interleukin-1 beta [IL-1 beta]) secreted from the gingival crevicular fluid (GCF) during orthodontic tooth movement. Materials and Methods: Eighteen female cats were included in this study. Animals were randomly divided into three groups (estrous, anestrous, and ovariectomized groups), each having six queens. Estrous was induced by administration of 150 IU equine chorionic gonadotropin (eCG) to queens of the estrous group. A closed-coil spring, applied with 80 g of tipping force to the canine, was attached between the maxillary canine and mini-implant. GCF was collected on days 0, 6, and 12 from each cat to examine PGE(2) and IL-1 beta during orthodontic tooth movement in cats. The PGE(2) and IL-1 beta levels were determined with enzyme-linked immunosorbent assay. Results: There was no significant difference (P > .05) between anestrous and the ovariectomized groups in terms of tooth movement on days 6 and 12 of distalization. In contrast, tooth movement in the estrous group was lower (P < .05) than in the remaining two groups (anestrous and ovariectomized). The mean PGE(2) and IL-1 beta levels of the canine teeth of the estrous groups were significantly lower than the remaining two groups on days 6 and 12 (P < .05) of coil spring applications. Conclusions: These results indicate that ovarian activity can affect orthodontic tooth movement and GCF levels of IL-1 beta and PGE(2) in cats. (Angle Orthod. 2013;83:70-75.)Öğe Effects of early bilateral mandibular first molar extraction on condylar and ramal vertical asymmetry(Springer Heidelberg, 2013) Halicioglu, Koray; Celikoglu, Mevlut; Caglaroglu, Murat; Buyuk, Suleyman Kutalmis; Akkas, Ismail; Sekerci, Ahmet ErcanThis study aims to investigate the mandibular vertical asymmetry in a group of adult patients who had early bilateral mandibular first molar extractions. Mandibular asymmetry index measurements (condylar, ramal, and condylar plus ramal) were made on the panoramic radiographs of a study group including 30 subjects (mean age, 18.22 +/- 1.30 years) and a control group of 25 subjects (mean age, 18.24 +/- 1.17 years). Group I comprised the control group patients with no extractions and had excellent class I relationships, no missing teeth, and slight or moderate anterior crowding. Group II included patients with a bilateral mandibular first molar teeth extracted before the age of 12 years. Student's t test was used for the comparison of asymmetry index values between the groups. A paired t test was used to determine possible statistically significant differences between the sides for condylar, ramal, and condylar plus ramal height measurements. No group showed statistically significant side-specific differences for posterior vertical height measurements. Condylar asymmetry index (CAI), ramal asymmetry index, and condylar plus ramal asymmetry index measurements were not statistically different between the groups (p > 0.05). CAI values were significantly high when compared with the 3 % threshold value in the both groups, but comparisons between the groups were not statistically significant. This article investigates the effects of early bilateral mandibular molar teeth extraction that has never been investigated in the literature. The present study showed that the lengths of the condylar, ramal, and condylar plus ramal height were less in the study group than in a well-matched control group of without extraction.Öğe Investigation of prevalence and characteristics of mesiodens in a non-syndromic 11256 dental outpatients(Verduci Publisher, 2013) Colak, H.; Uzgur, R.; Tan, E.; Hamidi, M. M.; Turkal, M.; Colak, T.AIM: To investigate the prevalence of mesiodens in a sample of Turkish dental patients and their distribution among genders. PATIENTS AND METHODS: A retrospective study was performed using panoramic radiography of 11256 patients, who ranged in age from 15 to 55 years old. All data (age, sex and or syndrome) were obtained from the patient files and analyzed for mesiodens. Statistical evaluation of the presence of mesiodens related to gender was performed by the Pearson chi-squared test. RESULTS: Mesiodens was detected in 15 subjects (0.13%). The prevalence of mesiodens for females and males was 0.20% and 0.057%, respectively (p = 0.037). The most commonly observed mesiodens was maxillary canine-like type (60%). Most of the mesiodens (67%) were found in the vertical position, followed by horizontal position (33%). The age and sex distribution, number of mesiodens per patient, shape, direction, size, and effect on permanent maxillary incisors are also presented in this study. The most common complication caused by mesiodens was midline of the permanent incisors. CONCLUSIONS: Mesiodens is an uncommon developmental anomaly in Turkish dental patients. Early diagnosis allows the most appropriate treatment, often reducing the extent of surgery, orthodontic treatment and possible complications.Öğe Patterns of third-molar agenesis in an orthodontic patient population with different skeletal malocclusions(E H Angle Education Research Foundation, Inc, 2012) Celikoglu, Mevlut; Kamak, HasanObjective: To examine the relationship between third-molar agenesis and different skeletal malocclusion patterns. Materials and Methods: Pretreatment records of 1046 orthodontic patients (aged 13-17 years; mean age, 14.07 +/- 1.27) were used. Third-molar agenesis was calculated with respect to genders, number of missing teeth, jaws, and skeletal malocclusion patterns. The Pearson chi-square test was performed to determine potential differences. Results: Among the 1046 subjects, 237 subjects were diagnosed with third-molar agenesis (22.7%) with no statistical gender difference (P >.05). It was more common in the maxilla than in the mandible or in both jaws (P <.01). The prevalence of patients with a third-molar agenesis was the most commonly found type (P <.001). The prevalence of third-molar agenesis in those with a Class III malocclusion was significantly higher than in those with Class I or Class II (P <.05). However, there was similar prevalence among the hyper-divergent (24.5%), normal (23.8%), and hypodivergent (19.2%) groups (P>.05). Conclusion: These results suggest that agenesis of the third molar does not depend on vertical patterns of the skeletal malocclusions, but does depend on sagittal skeletal malocclusions in this orthodontic patient population. (Angle Orthod. 2012;82:165-169.)Öğe Determination and Application of Pont's Index in Turkish Population(Hindawi Ltd, 2012) Celebi, Ahmet Arif; Tan, Enes; Gelgor, Ibrahim ErhanDisharmony between tooth size and dental arch size induces orthodontic problems. So, dental indices were identified by various authors. One of these is Pont who determined a method of prediction of the ideal dental arch width which has become known as Pont's Index. The purpose of this study was to assess the applicability of Pont's Index to a Turkish population and to compare the results with those obtained from studies of different ethnic subjects. The sample comprised 64 male subjects and 78 female subjects with age range from 14 to 15 years. Measurements were obtained directly from plaster casts; they included mesiodistal crown diameters of the four maxillary incisors, as well as interpremolar and intermolar maxillary arch widths as specified by Pont. Correlation coefficients determined between the measured arch width values and those calculated according to Pont's Index were low in all cases, with r values ranging from 0.02 to 0.36. It was concluded that Pont's Index should not be used to predetermine ideal arch width values in Turkish individuals.Öğe Assessment of the Prevalence of Pulp Stones in a Sample of Turkish Central Anatolian Population(Hindawi Publishing Corporation, 2012) Colak, Hakan; Celebi, Ahmet Arif; Hamidi, M. Mustafa; Bayraktar, Yusuf; Colak, Tugba; Uzgur, RecepObjective. The aim of this study was to determine the prevalence of pulp stones (PS) in a Turkish dental patient population with respect to sexes and dental localization in relation between sex and this anomaly. Materials Methods. A retrospective study was performed using bitewing radiographs of 814 patients ranging in age from 15 to 65. All data (age, sex, and location) was obtained from the files. These patients were analyzed for pulp stones. Descriptive characteristics of sexes, jaws, and dental localization were recorded. The Pearson chi-squared test was used. Results. Of the patients, 462 (56.8%) were female and 352 (43.2%) were male. Sixty (12%) had one or more teeth that contained pulp stones. Pulp stones were identified in 518 (63.6%) of the subjects and in 2391 (27.8%) of the teeth examined. Pulp stone occurrence was significantly more common in the females than in males. With the increasing of age, the prevalence of pulp stones increased. Molars had statistically more pulp stones than premolars. Pulp stones were significantly more common in the maxilla compared with mandible. Conclusion. Prevalence of pulp stones in Turkish population was 27.8% but further larger-scale studies are required to assess its prevalence in the general population to compare it with other ethnic groups.Öğe Facial soft tissue thickness among skeletal malocclusions: is there a difference?(Korean Assoc Orthodontists, 2012) Kamak, Hasan; Celikoglu, MevlutObjective: The purpose of this study was to determine the soft tissue thickness of male and female orthodontic patients with different skeletal malocclusions. Methods: Soft tissue thickness measurements were made on lateral cephalometric radiographs of 180 healthy orthodontic patients with different skeletal malocclusions (Class I: 60 subjects, Class II: 60 subjects, Class III: 60 subjects). Ten measurements were analyzed. For statistical evaluation, one-way ANOVA and Kruskal-Wallis tests were performed. Least significant difference (LSD) and Dunnet T3 post hoc tests were used to determine the individual differences. Results: Soft tissue thicknesses were found to be greater for men than for women. Statistically significant differences among the skeletal groups were found in both men and women at the following sites: labrale superius, stomion, and labrale inferius. The thickness at the labrale superius and stomion points in each skeletal type was the greatest in Class III for both men and women. On the other hand, at the labrale inferius point, for both men and women, soft tissue depth was the least in Class III and the greatest in Class II. Conclusions: Soft tissue thickness differences among skeletal malocclusions were observed at the labrale superius, stomion, and labrale inferius sites for both men and women. [Korean J Orthod 2012;42(1):23-31]Öğe Histopathologic investigation of the effects of prostaglandin E2 administered by different methods on tooth movement and bone metabolism(Korean Assoc Orthodontists, 2012) Caglaroglu, Murat; Erdem, AbdulvahitObjective: The aim of this study was to investigate and compare the in vivo effects of prostaglandin E2 (PGE2) administered by different methods on orthodontic tooth movement and bone metabolism macroscopically, histopatologically, and biochemically. Methods: Forty-five young adult New Zealand rabbits were randomly divided into 3 experimental groups (n = 10/group), 1 positive control group (n = 10), and 1 negative control group (n = 5). The experimental rabbits were fitted with springs exerting 20-g reciprocal force on the maxillary incisors and PGE2 (10 mu g/mL) was administered by the intravenous, submucosal, or intraligamentous route after appliance insertion and on days 1, 3, 7, and 14 thereafter. All rabbits were sacrificed on day 21 and their premaxillae were resected for histologic evaluation. Results: Tooth movement was observed in the experimental and positive control groups, but the intraligamentous PGE2 group had the highest values of all analyzed parameters, including serum calcium and phosphorus levels and osteoclastic and osteoblastic populations (p < 0.001). Conclusions: Submucosal and intraligamentous PGE2 administration significantly increases orthodontic tooth movement and bone metabolism, but the intraligamentous route seems to be more effective. [Korean J Orthod 2012;42(3):118-128]Öğe Prevalence of Root Dilacerations in Central Anatolian Turkish Dental Patients(Univ West Indies Faculty Medical Sciences, 2012) Colak, H.; Bayraktar, Y.; Hamidi, M. M.; Tan, E.; Colak, T.Objective: The aim of this study was to determine, retrospectively, the prevalence and distribution of the dilaceration of the root for each tooth-type in a sample of Central Anatolian Turkish population by using panoramic radiographs. Method: Panoramic radiograhs of 6912 patients (3860 women and 3052 men, mean age 29.04 years, range, 15 to 50 years) were examined for the presence of root dilacerations. Chi-square test was also used to compare the prevalence of dilacerations between male and female subjects and upper and lower jaws. Results: Data showed that 1108 (16.0%) of these subjects had one or more teeth that were dilacerated and these were detected in 466 (15.2%) males and 642 (16.6%) females. Statistical analysis (chi(2) test) showed a significant difference in the prevalence of dilaceration among male and female patients. Mandibular third molars were dilacerated most often (3.76%), followed by mandibular second molars (1.81%). Dilaceration was found in 1.23% of maxillary second premolars and 1.23% of mandibular second molars. Conclusion: Root dilacerations are not uncommon among Turkish dental patients, and their early detection could be important in treatment problems associated with it. However, further larger scale studies are required to assess its prevalence in the general population in order to compare it with other ethnic groups.