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The effect of dexmedetomidine on myocardial ischemia reperfusion injury in streptozotocin induced diabetic rats
Arslan, Mustafa; Poyraz, Fatih; Kiraz, Hasan Ali; Alkan, Metin; Kip, Gülay; Erdem, Özlem; Çomu, Faruk Metin (Anaesthesia Pain & Intensive Care, 2015)Objective: Ischemia/reperfusion (I/R) injury is an important cause of myocardial damage by means of oxidative, inflammatory, and apoptotic mechanisms. The aim of the present study was to examine the potential cardio-protective ... -
Effect of Fullerenol C60 on Erythrocyte Deformability During Ischaemia-Reperfusion Injury of Lower Extremity in Diabetic Rats
Kip, Gülay; Kartal, Hakan; Çomu, Faruk Metin; Polat, Yücel; Arslan, Mustafa; Küçük, Ayşegül (Gazi Univ, Fac Med, 2019)Background: Fullerenol, a water-soluble C60-fullerene derivative synthesized by Chiang et al, has been demonstrated to be able to scavenge free radicals in vitro and in vivo. Although its protective effects have been already ... -
Effect of Low and High Dose Sugammadex on Erythrocyte Deformability in Streptozotocin- Induced Diabetic Rats
Kiraz, Hasan Ali; Turgut, Hüseyin Cihad; Kartal, Seyfi; Çomu, Faruk Metin; Kip, Gülay; Alkan, Metin; Aydın, Muhammed Enes (2015)Amaç: Eritrosit deformabilitesi eritrosit membranının özel yapısı ile ilgili bir fonksiyon olup, hücrenin dağılmadan oksijen taşımasına olanak sağlar. Diyabette görülen bozulmuş eritrosit deformabilitesi eritrosit agregasyonu ...