Yazar "Turk, Mustafa" için listeleme
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Anti Wnt-1 Monoclonal Antibody's Conjugated with Gold Nanoparticles, Induced Apoptosis on MCF-7 Breast Cancer Cell Lines
Azar, Mehdi Tayybi; Saglam, Necdet; Turk, Mustafa (Trans Tech Publications Ltd, 2019)Wnt-beta Catenin Pathway has an important role in many cancers. Wnt-1 protein from Wnt protein family that regulate this pathway has a special effect on the development of breast cancer. Monoclonal antibodies attach to ... -
Anti-Epidermal Growth Factor Receptor Aptamer and Antibody Conjugated SPIONs Targeted to Breast Cancer Cells: A Comparative Approach
Tutkun, Lutfiye; Gunaydin, Esra; Turk, Mustafa; Kutsal, Tulin (Amer Scientific Publishers, 2017)Cancer is still one of the major reasons of illness and death throughout the world. Wide range of cancer types occur in many organs like breast, liver, lung, colon etc. The surface characteristics of these cells change, ... -
Antimicrobial, antioxidant, cytotoxic and apoptotic activities of Satureja khuzestanica
Soltanzadeh, Hossein; Acik, Leyla; Turk, Mustafa; Houshmand, Massoud; Shahsavari, Gholamreza (Gazi Univ, Fac Med, 2018)Objective: Natural products with antimicrobial effect are currently investigated in order to eliminate the use of synthetic antibiotics that cause the resistance of microorganisms. This study determines the antibacterial, ... -
Antisense oligonucleotide delivery to cancer cell lines for the treatment of different cancer types
Kilicay, Ebru; Erdal, Ebru; Hazer, Baki; Turk, Mustafa; Denkbas, Emir Baki (Taylor & Francis Ltd, 2016)Amphiphilic poly(3-hydroxylalkanoate) (PHA) copolymers find interesting applications in drug delivery. The aim of this study was to prepare nucleic acid adsorbed on (PHB-b-PEG-NH2) nanoparticle platform for gene delivery. ... -
Apoptotic and necrotic effects of carboxylated quercetin/polyethylenimine complex on HeLa cells
Ulug, Murat; Turk, Mustafa; Oguztuzun, Serpil; Menemen, Yusuf; Kahraman, Gulten (Academic Journals, 2011)The effects of quercetin (Q), carboxylated quercetin (CQ) and carboxylated quercetin/polyethylenimine (CQ/PEI) complex on HeLa cell cultures were investigated. Firstly, carboxylated quercetin was acquired through hydroxyl ... -
Apoptotic and necrotic effects of plant extracts belonging to the genus Alchemilla L. species on HeLa cells in vitro
Turk, Mustafa; Kaya, Bulent; Menemen, Yusuf; Oguztuzun, Serpil (Academic Journals, 2011)Apoptotic and necrotic effects of plant extracts belonging to the genus Alchemilla on HeLa cells were investigated. The ratio of viable cells was determined by cell counter. Double staining method for the determination of ... -
Aptamer-functionalized magnetic graphene oxide nanocarrier for targeted drug delivery of paclitaxel
Hussien, Nizamudin Awel; Isiklan, Nuran; Turk, Mustafa (Elsevier Science Sa, 2018)Targeted drug delivery has come out as a golden system owing to its capability to reduce side effects and increase efficacy. The application of graphene oxide (GO) based nanomaterials for targeted delivery has recently ... -
Autologous stem cell-derived chondrocyte implantation with bio-targeted microspheres for the treatment of osteochondral defects
Bozkurt, Murat; Asik, Mehmet Dogan; Gursoy, Safa; Turk, Mustafa; Karahan, Siyami; Gumuskaya, Berrak; Dogan, Metin (Bmc, 2019)Background Chondral injury is a common problem around the world. Currently, there are several treatment strategies for these types of injuries. The possible complications and problems associated with conventional techniques ... -
Bi-layered constructs of poly(glycerol-sebacate)-beta-tricalcium phosphate for bone-soft tissue interface applications
Tevlek, Atakan; Hosseinian, Pezhman; Ogutcu, Cansel; Turk, Mustafa; Aydin, Halil Murat (Elsevier Science Bv, 2017)This study aims to establish a facile protocol for the preparation of a bi-layered poly(glycerol-sebacate) (PGS)/beta-tricalcium phosphate (beta-TCP) construct and to investigate its potential for bone-soft tissue engineering ... -
Biocompatible and biodegradable poly(Tannic Acid) hydrogel with antimicrobial and antioxidant properties
Sahiner, Nurettin; Sagbas, Selin; Sahiner, Mehtap; Silan, Coskun; Aktas, Nahit; Turk, Mustafa (Elsevier, 2016)A novel resourceful bulk poly(Tannic Acid) (p(TA)) hydrogel was prepared by crosslinking TA molecules with an epoxy crosslinker, trimethylolpropane triglycidyl ether (TMPGDE), in an autoclave at 90 degrees C for 2 h. The ... -
Bioengineering functional copolymers. XV. Synthesis of organoboron amide-ester branched derivatives of oligo(maleic anhydride) and their interaction with HeLa and L929 fibroblast cells
Kahraman, Gulten; Turk, Mustafa; Rzayev, Zakir M. O.; Unsal, M. Elif; Soylemez, Ernur (Inst Organic Chem And Biochem, 2011)Novel bioengineering functional organoboron oligomers were synthesized by (i) amidolysis of oligo(maleic anhydride) (OMA) with 2-aminoethyldiphenylborinate (2-AEPB), (ii) esterification of organoboron oligomer (OMA-B) with ... -
Calcified and mechanically debilitated three-dimensional hydrogel environment induces hypertrophic trend in chondrocytes
Celik, Ekin; Bayram, Cem; Akcapinar, Rumeysa; Turk, Mustafa; Denkbas, Emir Baki (Sage Publications Ltd, 2016)Currently, the main focus on tissue engineering strategies is to mimic the extracellular matrix of the related tissues. Many studies accomplished to build tissue scaffolds to act as the natural surroundings of the specific ... -
Characterization of chondrocytes cultured on catechin-loaded alginate-chitosan scaffolds
Turk, Mustafa; Karahan, Siyami; Cinar, Miyase; Kucuk, Sebnem; Dincel, Gungor Cagdas (Informa Healthcare, 2013)Bovine chondrocytes were seeded into scaffolds of a high molecular weight chitosan and alginate with a pore size of 50-350 mu m with or without catechin. In polymerase chain reaction (PCR), unlike type II, collagen type I ... -
Cytotoxicity and apoptotic effects of nickel oxide nanoparticles in cultured HeLa cells
Ada, Kezban; Turk, Mustafa; Oguztuzun, Serpil; Kilic, Murat; Demirel, Mehmet; Tandogan, Nisa; Latif, Ozturk (Via Medica, 2010)The aim of this study was to observe the cytotoxicity and apoptotic effects of nickel oxide nanoparticles on human cervix epithelioid carcinoma cell line (HeLa). Nickel oxide precursors were synthesized by an nickel ... -
Decreased UV-filtering ability of corneal epithelium may be the cause of stromal pathologies in keratoconus
Cagil, Nurullah; Yildiran, Fatma Azize Budak; Ugurlu, Nagihan; Tuncer, Sema; Turk, Mustafa; Caglayan, Mehtap; Sevli, Serhat (Assoc Research Vision Ophthalmology Inc, 2017)… -
Downregulation of ABCE1 via siRNA affects the sensitivity of A549 cells against chemotherapeutic agents
Kara, Goknur; Tuncer, Sema; Turk, Mustafa; Denkbas, Emir Baki (Humana Press Inc, 2015)ATP-binding cassette E1 (ABCE1) is involved in several biological functions in cancer cells such as tumor proliferation, antiapoptotic pathway and chemoresistance mechanism. This work aimed to investigate the alterations ... -
The effect of calcium chloride concentration on alginate/Fmoc-diphenylalanine hydrogel networks
Celik, Ekin; Bayram, Cem; Akcapinar, Rumeysaa; Turk, Mustafa; Denkbas, Emir Baki (Elsevier Science Bv, 2016)Peptide based hydrogels gained a vast interest in the tissue engineering studies thanks to great superiorities such as biocompatibility, supramolecular organization without any need of additional crosslinker, injectability ... -
Effects of ABCE1 Down-Regulation by RNAi on Chemosensitivity of Lung Cancer Cells
Kara, Goknur; Tuncer, Sema; Turk, Mustafa; Denkbas, Emir Baki (Int Inst Anticancer Research, 2014)… -
Effects of B2O3 (boron trioxide) on colon cancer cells: our first-step experience and in vitro results
Albuzi, Ozgur; Dulger, Dilek; Tunali, Beste Cagdas; Aydin, Feray; Yalcin, Selim; Turk, Mustafa (Tubitak Scientific & Technical Research Council Turkey, 2019)Boron oxide (B2O3) is derived from dehydration of boric acid and is a colorless, semitransparent, crystalline compound that is moderately soluble in water. On the other hand, boron oxide is chemically hygroscopic. This ... -
Fabrication and characterization of gold-nanoparticles/chitosan film: a scaffold for L929-fibroblasts
Turk, Mustafa; Tamer, Ugur; Alver, Erol; Ciftci, Hakan; Metin, Aysegul U.; Karahan, Siyami (Taylor & Francis Ltd, 2013)The objective of the present study was to fabricate a gold nanoparticle crosslinked chitosan (Ch/AuNPs) composite film simple and to evaluate its use as a carrier matrix for L929-fibroblasts. L929-fibroblasts were seeded ...