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Effect of alprostadil on erythrocyte deformability in ischemia reperfusion injury
(Comenius Univ, 2015)BACKGROUND: Ischemia reperfusion injury (I/R) in lower extremity is a frequent and important clinical phenomenon. Protective effect of alprostadil on local and distant organ injury due to I/R has been well-documented but ... -
Effect of levosimendan on erythrocyte deformability during myocardial ischaemia-reperfusion injury
(Comenius Univ, 2015)Diabetes mellitus (DM) is a chronic metabolic disorder accompanied by an increase in oxidative stress. Ischaemia-reperfusion (IR) injury is a cascade of events initiated by tissue ischaemia. The cellular damage produced ... -
The effects of low and high doses of sugammadex on kidney tissue in streptozotocin-induced diabetic rats
(Comenius Univ, 2015)BACKGROUND: Sugammadex is primarily excreted via renal route. We investigated effects of low and high doses of sugammadex (16 mg/kg versus 96 mg/kg) on renal tissue samples of streptozotocin-induced diabetic rats. MATERIAL ... -
Investigation of Effects of Propofol and Vitamin C Administration on Hepatic and Renal Tissue in Diabetic Rats
(Gazi Univ, Fac Med, 2015)Obective: A close relationship between diabetic complications and lipid peroxidation is known. It was shown that in diabetic rat pharmacodynamics and pharmacokinetics of propofol was changed. We aim to investigate effects ... -
Effects of lornoxicam and intravenous ibuprofen on erythrocyte deformability and hepatic and renal blood flow in rats
(Dove Medical Press Ltd, 2016)Background: Change in blood supply is held responsible for anesthesia-related abnormal tissue and organ perfusion. Decreased erythrocyte deformability and increased aggregation may be detected after surgery performed under ... -
Effects of alprostadil and iloprost on renal, lung, and skeletal muscle injury following hindlimb ischemia-reperfusion injury in rats
(Dove Medical Press Ltd, 2016)Objectives: To evaluate the effects of alprostadil (prostaglandin [PGE1] analog) and iloprost (prostacyclin [PGI2] analog) on renal, lung, and skeletal muscle tissues after ischemia reperfusion (I/R) injury in an experimental ... -
Effect of picroside II on erythrocyte deformability and lipid peroxidation in rats subjected to hind limb ischemia reperfusion injury
(Dove Medical Press Ltd, 2016)Background: Ischemia reperfusion injury (I/R) in hind limb is a frequent and important clinical phenomenon. Many structural and functional damages are observed in cells and tissues in these kinds of injuries. In this study, ... -
Vitamin C ameliorates high dose Dexmedetomidine induced liver injury
(Comenius Univ, 2016)BACKGROUND: We investigated whether vitamin C has protective effects on rat liver tissue treated with different dexmedetomidine doses. MATERIAL AND METHODS: Thirty five wistar albino rats were randomly divided into 5 groups ... -
Effect of dexmedetomidine on ischemia-reperfusion injury of liver and kidney tissues in experimental diabetes and hepatic ischemia-reperfusion injury induced rats
(Anaesthesia Pain & Intensive Care, 2016)Background: Reperfusion following ischemia can lead to more injuries than ischemia itself especially in diabetic patients. The aim of this study was to evaluate the effect of dexmedetomidine on ischemia-reperfusion injury ... -
Effects of intravenous ibuprofen and lornoxicam on erythrocyte deformability in rats undergoing hind limb ischemia reperfusion injury
(Comenius Univ, 2016)BACKGROUNDAND AIM: Acute hind limb ischemia reperfusion (I/R) injury is a common consequence of abdominal aorta cross-clamping during aortic surgery. Erythrocyte deformability is affected by I/R process and may lead to ... -
Flufenamic acid prevents behavioral manifestations of salicylate-induced tinnitus in the rat
(Termedia Publishing House Ltd, 2016)Introduction: Tinnitus is defined as a phantom auditory sensation, the perception of sound in the absence of external acoustic stimulation. Given that flufenamic acid (FFA) blocks TRPM2 cation channels, resulting in reduced ... -
Interleukin-6 and hepcidin expression changes in cardiac tissue of long-term trained and untrained rats after exhaustive exercise
(Tubitak Scientific & Technical Research Council Turkey, 2017)Background/aim: Exercise benefits the cardiovascular system, but strenuous exercise can cause cardiac damage and induce cytokine production, particularly that of interleukin-6 (IL-6). Hepcidin, which is primarily regulated ... -
Association of physical activity and obesity status for individuals between the ages of 18-30 via bioelectrical impedance analysis device and metabolic holter measurements
(Mattioli 1885, 2017)Obesity, according to its simplest definition, is excessive accumulation of fat in the body. Obesity is a health problem that is observed commonly in almost all societies and it is starting to become a global epidemic. In ... -
The Effects of Simvastatin on Ischemia Reperfusion Injury in an Experimental Colon Anastomosis Model
(Springer India, 2017)Anastomotic leakage is more frequently reported in colonic anastomoses. Ischemia reperfusion injury is one of the main reasons for anastomotic leakage. Simvastatin is known to prevent tissue damage induced by free oxygen ... -
Effect of apelin-13 on erythrocyte deformability during ischaemia-reperfusion injury of heart in diabetic rats
(Comenius Univ, 2017)OBJECTIVES: Erythrocyte deformability and plasma viscosity are of crucial importance for the perfusion of tissues and organs. The aim of this study was to evaluate the effect of apelin-13 on erythrocyte deformability during ... -
The Effect of Picroside-2 on Erythrocyte Deformability and Lipid Peroxidation in StreptozotocinInduced Diabetic Rats Subjected to Left Anterior Descending Artery-Ischaemia Reperfusion
(2017)Aim: Diabetes mellitus (DM) is a chronic metabolic disorder principally characterized by an elevation in oxidative stress levels. Ischaemia-reperfusion (IR) injury starts a cascade of events that lead to tissue ischaemia ... -
Protective effect of erdosteine on erythrocyte deformability in a rat model of lower limb ischemia/reperfusion injury
(Tubitak Scientific & Technical Research Council Turkey, 2018)Background/aim: The protective effect of erdosteine on local and distant organ injury due to ischemia/reperfusion has been well documented but its effect on erythrocyte deformability needs further investigation. Our aim ... -
Effects of dexmedetomidine and thymoquinone on erythrocyte deformability in lower limb ischemia reperfusion injury in streptozotocin-induced diabetic rats
(Comenius Univ, 2018)OBJECTIVE: In this study we aimed to evaluate the effect of dexmedetomidine and thymoquinone on erythrocyte deformability in lower limb ischaemia-reperfusion (IR) injury in streptozotocin-induced diabetic rats. MATERIAL ... -
Effect of cerium oxide on erythrocyte deformability in rat lower extremity ischemia reperfusion injury
(Comenius Univ, 2018)BACKGROUND: Cerium oxide is the oxide form of cerium, which has protective effects in ischemia reperfusion (I/R) injury. The purpose of our study was to look into the effects of this rare-earth metal on erythrocyte ...