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Effects of intravenous ibuprofen and lornoxicam on erythrocyte deformability in rats undergoing hind limb ischemia reperfusion injury
(Comenius Univ, 2016)BACKGROUNDAND AIM: Acute hind limb ischemia reperfusion (I/R) injury is a common consequence of abdominal aorta cross-clamping during aortic surgery. Erythrocyte deformability is affected by I/R process and may lead to ... -
Effects of lornoxicam and intravenous ibuprofen on erythrocyte deformability and hepatic and renal blood flow in rats
(Dove Medical Press Ltd, 2016)Background: Change in blood supply is held responsible for anesthesia-related abnormal tissue and organ perfusion. Decreased erythrocyte deformability and increased aggregation may be detected after surgery performed under ... -
The effects of low and high doses of sugammadex on kidney tissue in streptozotocin-induced diabetic rats
(Comenius Univ, 2015)BACKGROUND: Sugammadex is primarily excreted via renal route. We investigated effects of low and high doses of sugammadex (16 mg/kg versus 96 mg/kg) on renal tissue samples of streptozotocin-induced diabetic rats. MATERIAL ... -
The effects of low-high doses of dexmedetomidine on erythrocyte deformability in rats
(Comenius Univ, 2012)Background: Dexmedetomidine is an anesthetic agent frequently used for sedation, intensive care units, and general anesthesia. The purpose of our study was to investigate the effect of two different doses of dexmedetomidine ... -
The effects of magnesium sulphate on the contractile activity of uterus in an animal model of preeclampsia
(7847050 Canada Inc, 2014)Purpose: This study was undertaken to evaluate the effects of magnesium sulfate (MgSO4) on the contractile activity of the uterus in a pregnant rat model of preeclampsia induced by N-nitro-arginine methyl ester (L-NAME). ... -
Effects of N-Acetylcysteine and N-Acetylcysteine Amide on Erythrocyte Deformability and Oxidative Stress in a Rat Model of Lower Extremity Ischemia-Reperfusion Injury
(HINDAWI LTD, 2020)N-acetylcysteine (NAC) is an antioxidant which works as a free radical scavenger and antiapoptotic agent. N-acetylcysteine-amide (NACA) is a modified form of NAC containing an amide group instead of a carboxyl group of ... -
The effects of propofol and memantine on erythrocyte deformability
(Comenius Univ, 2014)Objective: Propofol is an intravenous general anesthetic with a primary hypnotic effect. Memantine is an NMDA receptor antagonist that has been shown to reverse changes in memory and synaptic plasticity in animal models. ... -
Effects of Sevoflurane and Desflurane on Oxidant/Antioxidant Status of Young Versus Old Rat Liver Tissues
(Medwell Online, 2008)Anesthetic agents modulate on oxidant/antioxidant activity. This study aimed to evaluate the effects of desflurane and sevoflurane anesthesia on the oxidant/antioxidant activity in the liver of young and aged rats. The ... -
The Effects of Simvastatin on Ischemia Reperfusion Injury in an Experimental Colon Anastomosis Model
(Springer India, 2017)Anastomotic leakage is more frequently reported in colonic anastomoses. Ischemia reperfusion injury is one of the main reasons for anastomotic leakage. Simvastatin is known to prevent tissue damage induced by free oxygen ... -
Effects of the general anaesthetic agent, propofol, on erythrocyte deformability
(Comenius Univ, 2010)Objectives: Propofol is an anesthetic agent frequently used for sedation and general anesthesia. The purpose of our study was to investigate the effect of propofol, a general anesthetic, on erythrocyte deformability in ... -
Erkek sıçanlarda orşiektominin ve vitamin c desteğinin eritrosit deformabilitesi ve kemik mineral yoğunluğu üzerine etkilerinin incelenmesi
(2012)Amaç: Erkek osteoporozu (OP) klinik tıpta önemli bir sorun olmakla birlikte kadın OP'sine kıyasla daha az ilgi görmüştür ve kemik kaybında rolü olan mekanizmalar hala netleşmiş değildir. Patofizyolojisinde oksidatif stresin ... -
Flufenamic acid prevents behavioral manifestations of salicylate-induced tinnitus in the rat
(Termedia Publishing House Ltd, 2016)Introduction: Tinnitus is defined as a phantom auditory sensation, the perception of sound in the absence of external acoustic stimulation. Given that flufenamic acid (FFA) blocks TRPM2 cation channels, resulting in reduced ... -
Important anatomical structures used in paravaginal defect repair: cadaveric study
(Elsevier, 2004)Objective: To examine the variations and the anatomical characteristics of the tendinous arch of pelvic fascia (TAPF), the tendinous arch of levator ani (TALA) and the obturator fascia (Ofa) that are important structures ... -
Interleukin-6 and hepcidin expression changes in cardiac tissue of long-term trained and untrained rats after exhaustive exercise
(Tubitak Scientific & Technical Research Council Turkey, 2017)Background/aim: Exercise benefits the cardiovascular system, but strenuous exercise can cause cardiac damage and induce cytokine production, particularly that of interleukin-6 (IL-6). Hepcidin, which is primarily regulated ... -
Investigation of Effects of Propofol and Vitamin C Administration on Hepatic and Renal Tissue in Diabetic Rats
(Gazi Univ, Fac Med, 2015)Obective: A close relationship between diabetic complications and lipid peroxidation is known. It was shown that in diabetic rat pharmacodynamics and pharmacokinetics of propofol was changed. We aim to investigate effects ... -
Investigation of the effects of propofol and vitamin C administration on erythrocyte deformability in rats with streptozotocin-induced diabetes mellitus
(Comenius Univ, 2014)Purpose: In the current study we aim to investigate the effects of vitamin C and profol on red blood cell deformability in diabetic rats Materials and methods: Twenty- eight Wistar Albino rats were included in the study ... -
Investigation of the Effects of Sevoflurane and Desflurane on Erythrocyte Deformability in Transient Hyperglycemia
(2018)Aim: Micro and macrovascular complications due to long-term hyperglycemia are associated with increased mortality and morbidity. Erythrocytes exposed to hyperglycemia for a long time may cause morphological changes in ... -
Investigation of the effects of thymoquinone on erythrocyte deformability in sepsis treatment which created by cecal perforation in rat
(Comenius Univ, 2018)AIM: We aimed to study the effects of thymoquinone on erythrocyte deformability in an experimental model of sepsis given before or after the initiation of the sepsis model. METHOD: The animals were grouped as (n = 6) ... -
Kısa dönem antrenmanın iskelet kasında kaveolin ve VEGF ekspresyonu üzerine etkisi
(2013)Dayanıklılık egzersizi iskelet kası ve kardiyovasküler sistemde adaptif değişikliklere yol açmaktadır. Egzersiz anjiyogenezin önemli bir mediatörü olan vasküler endotelyal büyüme faktörünü (VEGF) indüklemektedir. Kaveolin-1 ...