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Öğe Efor dispnesinin nadir nedeni: Swyer James (mc leod) sendromu(2009) Şentürk, Erol; Ekici, Aydanur; Bulgun, Emel; Ekici, Mehmet; Karakoç, Tülay; Tireli, Gökhan; Altınkaya, VolkanSwyer James ya da Mc Leod Sendromu; unilateral hiperlüsen akciğer, hacim kaybı, mediastinal şift ve etkilenen tarafta daha küçük hiler gölge izlenmesi ile karakterize nadir bir hastalıktır. Pulmoner emboli, perfüzyon bozukluğu yapan diğer hastalıklar ve efor dispnesi yapan bazı hava yolu hastalıkları ile karışabilir. Bir kaç yıldır başka merkezlerde astım tanısı ile takip edilen 41 yaşında kadın olgu Swyer James Sendromu tanısı ile literatür bilgileri eşliğinde tartışıldı.Öğe Factors Associated With Quality of Life in Subjects With Stable COPD(Daedalus Enterprises Inc, 2015) Ekici, Aydanur; Bulçun, Emel; Karakoç, Tülay; Şentürk, Erol; Ekici, MehmetBACKGROUND: The purpose of this study was to assess the impact of bronchiectasis, anxiety and depression, and parameters of disease severity on health-related quality of life (HRQOL) in subjects with COPD. METHODS: Sixty-two subjects with stable COPD were selected for the study. The presence of bronchiectasis in all subjects with COPD was investigated by high-resolution computed tomography. Pulmonary function tests were performed. Dyspnea was assessed using the Modified Medical Research Council (MMRC) dyspnea scale. Psychological disorders were investigated using the Hospital Anxiety and Depression Scale (HADS), and the HRQOL was examined using the St George Respiratory Questionnaire (SGRQ). RESULTS: High-resolution computed tomography revealed that 44 of 62 (70.9%) subjects with COPD had bronchiectasis. There were no differences in pulmonary function tests, symptoms, activities, impact, SGRQ total scores, and HADS scores between COPD subjects with and without bronchiectasis. Pearson correlation analyses showed that there was no significant association between the presence of bronchiectasis, bronchial wall thickness, or severity of bronchial dilatation and all subscales of the SGRQ or HADS scores. Additionally, HADS scores showed significant positive association with all subscales of the SGRQ in all subjects. In linear regression analysis, a statistically significant relationship was found between the SGRQ total score and percent-of-predicted FEV1, percent-of-predicted diffusing capacity of the lung for carbon monoxide, MMRC score, and anxiety score, but the SGRQ total score was not associated with age, body mass index, total number of hospitalizations, P-aO2, or depression score. CONCLUSIONS: The presence of bronchiectasis in subjects with COPD does not impact HRQOL and psychological disorders. However, disease severity, dyspnea levels, and anxiety scores predict poor HRQOL.Öğe Kronik hava yolu hastalıklarında karbonmonoksit difüzyon değerleri(2009) Bulcun, Emel; Ekici, Aydanur; Şentürk, Erol; Arslan, Mesut; Akın, Ahmet; Ekici, MehmetKarbonmonoksit difüz yon (DLCO) ölçümü pulmoner gaz değişimi hakkında bilgi veren önemli ve kullanışlı noninvaziv bir testtir. Biz kronik hava yolu hastalıklarından astım, kronik obstrüktif akciğer hastalığı (KOAH) ve bronşektazi tanılı hastalarda difüzyon değerleri ile hastalık derecesi arasındaki ilişkiyi ve difüzyon değerlerini belirleyen faktörleri araştırdık. Çalışmaya astım tanılı 64, KOAH tanılı 78 ve bronşektazi tanılı 41 olmak üzere toplam 183 hasta ile sigara içmeyen 43 sağlıklı birey alındı. Atak döneminde olan 10 astımlı hasta hariç tüm hastalar stabil dönemde idi. Tüm olgulara solunum fonksiyon testi ve DLCO testi yapıldı. KOAH grubunda DLCO% ve DLCO/VA% değerleri astım, bronşektazi ve kontrol grubundan düşük bulundu (p0.001). Astımlı hastalarda atak döneminde DLCO% değeri; kontrol grubu, stabil dönemdeki orta ve ağır persistan astımlılardan yüksek bulundu (p0.05). Ağır persistan astımlılarda DLCO% değeri ise hafif persistan astımlılardan düşük bulundu (p0.05). Tüm hasta ve kontrol grubu birlikte değerlendirildiğinde, DLCO% ile FEV1% (r 0.49; p 0.0001), FEV1/FVC (r 0.36; p 0.0001) arasında ve DLCO/VA% ile FEV1% (r 0.16; p 0.01), FEV1/FVC (r 0.26; p 0.0001) arasında pozitif ilişki bulundu. Kronik hava yolu hastalıklarında DLCO kapasitesi obstrüksiyona paralel olarak azalmaktadır. DLCO değerleri kronik hava yolu hastalıklarının değerlendirilmesinde ve hastalık şiddetinin belirlenmesinde kullanılabilir.Öğe Personality profiles in patients with obstructive sleep apnea(Springer Heidelberg, 2013) Ekici, Aydanur; Ekici, Mehmet; Oğuztürk, Ömer; Karaboga, Işıl; Çimen, Dilay; Şentürk, ErolThe Minnesota Multiphasic Personality Inventory (MMPI) responses between snorers and obstructive sleep apnea (OSA) may be different. Thus, we compared the MMPI responses between snorers and OSA. A clinical-based cross-sectional survey. This is a survey of 94 treatment-naive sleep-disordered breathing (SDB) subjects. Clinical information, body mass index (BMI), 36-item Short Form Health Survey, the Turkish version of the MMPI, Epworth sleepiness scale (ESS), fatigue scale, attention-deficit scale, and polysomnography were collected. All patients with OSA and snorers was accepted as individuals with SDB (AHI > 0 events/h). The threshold of five apnea and hypopnea per hour of sleep was chosen to define both OSA and snorers. Disability profile is consisting of four or more MMPI clinical scale elevations. OSA patients compared to snorers have significantly higher absolute scores on hypochondriasis (Hs) (65.0 +/- 12.0 vs 58.4 +/- 7.9, p = 0.01, respectively). OSA patients compared to snorers have significantly higher rate of clinical elevation on both psychopathic deviance (13.0 vs 0 %, p = 0.03, respectively) and Hs (26.1 vs 3.3 %, p = 0.01, respectively). People with disability profile has lower the quality of life, a higher score for inattention, a higher fatigue scores, and higher sleepiness scores. The quality of life and attention deficit and daytime sleepiness scores were associated with total MMPI absolute score in individuals with SDB in bivariate analyses. Present study indicated that patients with OSAS compared to snorers displayed significantly more hyopchondriasis and psychopathic deviance personality characteristics. The daytime functions in individuals with sleep-disordered breathing may be influenced by the severity of psychopathology.
