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Öğe Assessment of sapheno-femoral junction continence in patients with primary adolescent varicocoele(Springer-Verlag, 2003) Karadeniz-Bilgili, M.Y.; Basar, H.; Simsir, I.; Ünal, B.; Batislam, E.Background. Although there is much evidence supporting a relationship between primary varicocoele and venous incompetence of the saphenofemoral junction in adults, there is no evidence for such a relationship during adolescence. Because of the effect of age and future occupation (standing upright for long periods) on the aetiology, pathogenesis and frequency of varicose veins of the lower extremity and incompetence of saphenofemoral junctions in adulthood, a comparison during adolescence is appropriate. Objective. On the basis of a close physiopathological and haemodynamic relationship between primary varicose veins and primary varicocoele, we decided to evaluate the competence of the saphenofemoral junctions in a selected group of adolescents affected by primary varicocoele and compare these results with age-matched healthy adolescents. Materials and methods. Twenty-five adolescents with primary varicocoele and 23 age-matched healthy controls were included in the study. In all cases physical examination and colour Doppler US was used to diagnose or exclude the presence of primary varicocoele and to evaluate the continence of the saphenofemoral junction. Results. On the right side, 10 of 25 varicocoele patients and on the left side 11 of 25 varicocoele patients had incompetence of the saphenofemoral junction. For the control patients the incidence was 2/23 on the right side and 4/23 on the left side. The difference is statistically significant. Conclustions. We demonstrated high concurrence of varicocoele and valvular incompetence of the saphenofemoral junction in a particular adolescent group. We suggest clinical examination and US assessment of the saphenofemoral junctions of adolescents affected by varicocoele in order to detect the early diagnosis of venous insufficiency of the lower limbs among these patients.Öğe Changes of Pudendal Somatosensory Evoked Potentials (PSEP) after Sildenafil Application in Erectile Dysfunction with Diabetic Polyneuropathy (PNP)(Wiley-Blackwell Publishing, Inc, 2004) Basar, M.; Ulkatan, S.; Batislam, E.; Yilmaz, E.; Uysal-Tan, F.; Basar, H.…Öğe A classification based on peak systolic velocity and end diastolic velocity predicts sildenafil citrate success(Informa Healthcare, 2003) Başar, M. Murad,; Atan, A.; Tekdoğan, Ümit Y.; Batislam, E.Objective: To attempt to predict the success rate of sildenafil citrate in erectile dysfunction patients using penile Doppler ultrasonography (PDU) measurements of peak arterial velocity and end diastolic velocity. Material and Methods: A total of 212 patients (age range 27-76 years) with vascular pathologies were included in the study. Following a PDU test, the patients were divided into arterial insufficiency, veno-occlusive dysfunction and mixed vascular pathology groups. Subsequently, patients were given sildenafil citrate 50 mg and re-evaluated 1 month later to determine its efficacy. If it was ineffective, the dose was increased to 100 mg and patients were reassessed. Arterial insufficiency and veno-occlusive dysfunction patients were classified into mild, moderate and severe groups depending on peak systolic and end diastolic velocities. Results: The overall response rate in patients with arterial insufficiency was 74.5%, regardless of the degree of arterial insufficiency or the dose of sildenafil. The severe arterial insufficiency group had a much better response to 100 mg compared to 50 mg doses of sildenafil. Although the 50 mg sildenafil dose was effective in patients with minimal veno-occlusive dysfunction, 100 mg was better than 50 mg to achieve adequate erection in the mild and severe veno-occlusive dysfunction groups. Conclusions: Sildenafil was ineffective in patients with severe arterial and venous insufficiency. PDU and a simple classification of PDU velocity measurements can provide some important clues to the prognosis of treatment and avoid overtreatment and unnecessary office visits.Öğe Continence recovery time after radical prostatectomy: implication of prostatic apical tumor(Edizioni Minerva Medica, 2013) Sipal, T.; Tuglu, D.; Yilmaz, E.; Atasoy, P.; Batislam, E.Aim. Despite the role of prostatic apex on post-radical prostatectomy incontinence (PPI) has been encountered, the impact of prostatic apex tumor on urinary recovery has been poorly adressed. We aimed to evaluate the effect of prostatic apex tumor on PPI. Methods. Between January 2008 and December 2011, a total 36 consecutive patients who underwent open retropubic radical prostatectomy (RRP) for prostate adenocancer (PCa) were analyzed. The patients were divided into two groups according to the presence of prostatic apical tumor. Urinary incontinence was assessed at regular intervals following RP using validated Incontinence Questionnaire-Short Form and 24-hour pad use based on patients' reports. Urinary continence was defined as wearing no pads. All patients' functional and oncological data were recorded. Results. Overall urinary continence rate at one year was 90%. There was a statistical difference between two groups in terms of urinary recovery (P=0.024). The 1 week, 1 month, 3 month, 6 months and 1 year postoperative continence rates were 28%, 50%, 85%, 92.9% and 92.9%, respectively, in patients with apex infiltration (-) group, compared with 0%, 22.7%, 45.5%, 72.7% and 86.4%, respectively, in patients with infiltration (+) group. Conclusion. The results provided that infiltration of the prostatic apex could significantly affect urinary continence recovery time after RP and advanced pathologic stage could be a risk for PPI.Öğe Ekstrakorporeal shock wave litotripsi sırasında hastalarda anksiyete-ağrı yoğunluğu ilişkisi(2003) Yılmaz, E.; Batislam, E.; Tuğlu, D.; Başar, M. M.; Boratav, C.; Başar, H.Bu çalışmada ESWL'nin hastalarda yarattığı anksiyetenin ağrı yoğunluğu üzerinde olumsuz etkisinin ortaya konması amaçlanmıştır. ASA fiziksel durum I-II 20-64 yaşları arasında (Ortalama: 39.1) 71 hasta çalışmaya alındı. Hastalar randomize iki gruba ayrıldı. Grup I'deki hastalara işlem ile ilgili ayrıntılı bilgi verilirken Grup Il'deki hastalara bilgi verilmedi. ESWL, 3.kuşak litotriptörlerden elektrohidrolik Litho3pter (PCK ) ile gerçekleştirildi. Analjezik amaçlı Fentanyl 1mugr/kg. işlemden 2 dakika önce intravenöz olarak uygulandı. Hastaların ağrı yoğunluğu işlemin birinci dakikası ve her 10 dakikada bir 0-100 mm Visuel Analog Scala (VAS) ile değerlendirildi. Durumluk ve sürekli anksiyete State/Trait Anxiety Inventory-Trait Anxiety (STAI-TA) ve State/Trait Anxiety Inventory-State Anxiety (STAI-SA) ile ölçüldü. Sürekli anksiyete skoru ile ağrı yoğunluğu arasında ilişki tespit edilmedi. Bununla birlikte STAI-TA skoru yüksek olan hastalarda ağn yoğunluğunun daha fazla olduğu gözlendi ve bu hastalarda ek analjezik ihtiyacı daha fazla oldu. işlem ile ilgili ayrıntılı bilgi verilen grupta durumluk anksiyete ve ağrı yoğunluğu skorları daha düşük bulundu. 20-29 yaş grubundaki genç kadınlarda ağn yoğunluğu daha fazla olup durumluk anksiyete düzeyleri daha yüksek olarak tespit edildi. ESWL, anksiyete yaratan bir işlemdir. Anksiyetesi daha yoğun olan hastalarda ağrı yoğunluğunun daha fazla olduğu ve bunun da hasta memnuniyetini olumsuz etkilediği düşünülmüştür. ESWL öncesi hastaya aynntılı bilgi verilmesi, genç kadınlarda daha çok ağrı ve anksiyete olabileceğinin bilinmesi ürolog için önemli avantaj yaratabilir.Öğe Erişkin polikistik böbrek hastalığında (EPBH) hemospermi nedeni olan veziküloseminalis kistleri(2003) Yılmaz, E.; Başar, M. M.; Tuğlu, D.; Başar, H.; Batislam, E.Adult polikistik böbrek hastalığı ile takip edilen 42 yaşında erkek hasta hemospermi yakınması ile başvurdu. Transrektal Ultrasonografi (TRUS) ve spesifik, non-spesifik kültürleri içeren detaylı değerlendirme sonrası hastada vezikülo seminalis kistleri dışında herhangi bir hemospermi nedeni saptanmadı. Anti-inflamatuar ve antibiyotik tedavisi sonrası hastanın yakınmaları düzeldi ve 6 aylık takipte hemospermi tekrarlamadı.Öğe Female sexual and hormonal status in patients with bronchial asthma: Relationship with respiratory function tests, psycho logic and somatic status (conferenceObject)(Wiley-Blackwell Publishing, Inc, 2004) Basar, M.; Ekici, A.; Ekici, M. S.; Kara, T.; Tuglu, D.; Batislam, E.…Öğe Four analgesic techniques for shockwave lithotripsy: Eutectic mixture local anesthetic is a good alternative(Mary Ann Liebert, Inc, 2003) Basar, H.; Yilmaz, E.; Ozcan, S.; Büyükkoçak, Ü.; Sari, F.; Apan, A.; Batislam, E.Background and Purpose: Various sedative and analgesic medication has been used for shockwave lithotripsy (SWL). The aim of this study was to evaluate the efficacy of different anesthesia modalities in these patients. Patients and Methods: One hundred patients were randomly divided into four groups. The first (Group F) received fentanyl 1 mug/kg intravenously (IV), the second (Group D) received diclofenac sodium 1 mg/kg-intramuscularly (IM), the third (Group T) received tramadol 1.5 mg/kg IM, and the fourth (Group E) was given 15 g of eutectic mixture local anesthetic (EMLA) cream containing lidocaine and prilocaine. After routine preoperative evaluation, all patients received midazolam 2 mg IV 5 minutes before lithotripsy for sedative premedication. In all groups, a supplemental 25-mug bolus of fentanyl was administered IV when patients complained of pain, moved, or grimaced in response to the shockwaves. Pain intensity was evaluated on a 0- to 100-mm visual analog scale (VAS). The level of sedation was determined using the Observer's Assessment of Alertness/Sedation (OAS/S). Side effects such as bradypnea, oxygen desaturation, bradycardia, pruritus, and nausea and vomiting were recorded. Results: There were no statistically significant differences among the four groups with regard to VAS, OAS/S scores, or side effects. In Group F, the mean arterial pressure was decreased significantly at 10 and 20 minutes. The patients in this group also manifested a decrease of oxygen saturation at the first, tenth, and twentieth minutes and the end of SWL. Conclusion: Application of EMLA cream was as safe and effective as fentanyl, diclofenac, and tramadol,. and reduction of the fentanyl dose during SWL was possible.Öğe Music decreases anxiety and provides sedation in extracorporeal shock wave lithotripsy(Elsevier Science Inc, 2003) Yilmaz, E.; Özcan, S.; Basar, M.; Basar, H.; Batislam, E.; Ferhat, M.Objectives. To evaluate the efficacy of music on sedation in extracorporeal shock wave lithotripsy (ESWL) treatment to compare its anxiolytic effects with those of midazolam. Methods. Ninety-eight urolithiasis patients were randomly divided into two groups. Hemodynamic parameters, including mean arterial pressure, heart rate, respiration rate, and oxygen saturation, were recorded in all patients. In 50 patients (group 1), 2 mg of midazolam was administered intravenously 5 minutes before ESWL. In group 2 (n = 48), music chosen by the patients was listened to with a headset and continued during the treatment. The visual analog scale (0 to 100 mm), Observer's Assessment of Alertness/Sedation Scale, State and Trait Anxiety Inventory-Trait Anxiety test, and State and Trait Anxiety Inventory-State Anxiety test were administered for the evaluation of pain, sedation level, and patient anxiety. Results. For the hemodynamic parameters, a statistically significant decrease in mean arterial pressure was noted at the end of the ESWL procedure in group 2 and in oxygen saturation from the 10th minute to the end of the treatment in group I. Although the visual analog scale, Observer's Assessment of Alertness/Sedation Scale, and State and Trait Anxiety Inventory-State Anxiety test did not show statistically significant differences, the State and Trait Anxiety Inventory-Trait Anxiety score was found to be lower in the music group (group 2) than in the midazolam group (group 1). Conclusions. With the anxiolytic effects of music, ESWL can be performed more effectively with the patient in a comfortable state. Listening to music by patients during the ESWL session is a feasible and convenient alternative to sedatives and anxiolytics.Öğe Protective effects of udenafil citrate, piracetam and dexmedetomidine treatment on testicular torsion/detorsion- induced ischaemia/reperfusion injury in rats(Wiley-Blackwell, 2016) Tuglu, D.; Yuvanc, E.; Ozan, T.; Bal, F.; Yilmaz, E.; Atasoy, P.; Batislam, E.The aim of this study was to investigate the antioxidant properties of udenafil citrate (1.4 mg kg(-1)-2.8 mg kg(-1)), dexmedetomidine 25 mu g kg(-1) and piracetam 200 mg kg(-1) administered on ipsilateral/contralateral testes after ischaemia in a rat model of testicular torsion/detorsion (T/D) and define its protective effect histologically. Fifty-six Wistar albino rats were included and randomly assigned into 6 groups. No intervention was performed in control group (Group 1, n = 8) and in torsion/detorsion group, (Group 2, n = 8). Udenafil 1.4 mg kg(-1) was given to torsion/detorsion group (Group 3, n = 10), udenafil 2.8 mg kg(-1) was given to torsion/detorsion group (Group 4, n = 10), piracetam 200 mg kg(-1) was given to torsion/detorsion group (Group 5, n = 10) and dexmedetomidine 25 mu g kg(-1) was given to torsion/detorsion group (Group 6, n = 10) intraperitoneally after 60 mins of testicular torsion. Biochemical and histopathological testicular injury were evaluated. When the tissue was examined by TOS values, Group 3, Group 4 and Group 5 were significantly lower than Group 2. In contrary Group 6 values were significantly higher than Group 2. The increasing doses of udenafil demonstrated antioxidant properties on the testis tissue and histopathological that protects the testicles.Öğe Relationship between nocturnal penile tumescance (NPT) rigi scan monitoring results, symptom scores (IIEF) and Sildenafil responses(Wiley-Blackwell Publishing, Inc, 2004) Basar, M.; Tuglu, D.; Yilmaz, E.; Basar, H.; Batislam, E.…Öğe Relationship with international index of erectile function (IIEF) and international prostate symptom scores' (IPSS) degrees in patienst with BPH after 50 years old(Wiley-Blackwell Publishing, Inc, 2004) Basar, M.; Yilmaz, E.; Unal, S.; Basar, H.; Batislam, E.…Öğe Retinal nerve fiber layer thickness in the acute phase of sildenafil treatment(Verduci Publisher, 2015) Ornek, K.; Tuglu, D.; Ogurel, R.; Ornek, N.; Yilmaz, E.; Batislam, E.OBJECTIVE: To evaluate the early effect of sildenafil on the retinal nerve fiber layer (RNFL) thickness. PATIENTS AND METHODS: Sixty eyes of 60 patients were enrolled in the study. The patients underwent RNFL analysis by scanning laser polarimetry (Nerve Fiber Analyzer, GDx VCC: 5.3.3; Laser Diagnostic Technologies, San Diego, CA, USA) before and after a single 100 mg dose of sildenafil. Sixty eyes of 60 volunteers of similar age and sex distribution were taken as the control group. The RNFL thickness parameters evaluated included temporal, superior, nasal, inferior, temporal (TSNIT) average, superior average (SA), inferior average (IA), TSNIT standard deviation (SD), and nerve fiber index (NFI). RESULTS: The mean age of the patients was 53,52 +/- 9,26 years. The mean pre- and post-treatment TSNIT, SA, IA, TSNIT SD, and NFI of the patients were 57.46 +/- 4.94 mu versus 56.90 +/- 4.59 microns (mu), 68.93 +/- 6,12 mu versus 67,79 +/- 5,49 mu, 66,71 +/- 7.10 mu versus 66.31 +/- 6.82 mu, 24 +/- 3.86 mu versus 23.40 +/- 4.05 mu, and 16.50 +/- 6.08 mu versus 14.92 +/- 6.76 mu, respectively. There were no statistically significant differences between pre- and post-treatment RNFL thicknesses (p = 0.527, p = 0.281, p = 0.754, p = 0.416, p = 0.185, respectively). CONCLUSIONS: A single 100 mg dose of sildenafil seems to have no unfavorable effect on RNFL thickness in the acute phase of treatment.Öğe Retroperitoneoscopic nephrectomy detected in an incidental renal cell carcinoma in an atrophic kidney(2003) Batislam, E.; Başar, M.M.; Ferhat, M.Herein, we present a case of retroperitoneoscopic simple nephrectomy for a small renal cell carcinoma in atrophic kidney. After search of Turkish indexes and Turkish publications in international indexes, we though that this case has been the first national publication of its kind.Öğe Sexual dysfunction in women with Fibromyalgia(Wiley-Blackwell Publishing, Inc, 2004) Aydin, G.; Basar, M.; Keles, I; Ergun, G.; Yildiz, O.; Batislam, E.…Öğe Sildenafil citrate for penile hemodynamic determination: An alternative to intracavernosal agents in Doppler ultrasound evaluation of erectile dysfunction(Elsevier Science Inc, 2001) Başar, M.M.; Batislam, E.; Altınok, D.; Yılmaz, E.; Basar, H.Objectives. To suggest a new noninvasive method for penile Doppler ultrasound (PDU) evaluation of erectile dysfunction using oral sildenafil citrate as an erection induction agent. Methods. A total of 20 patients admitted with the complaint of erectile dysfunction were evaluated by the short form of the international Index of Erectile Function. A total score of less than 25 was accepted as erectile dysfunction and PDU was performed. The initial penile study consisted of PDU examination under visual sexual stimulation (VSS), and the peak systolic velocity, end-diastolic velocity, and resistance index were recorded. Measurements of all the parameters were repeated on the same patients after intracavernosal papaverine, intracavernosal prostaglandin E-1 (PGE(1)), and oral sildenafil citrate administration, plus VSS. All patients had these four tests in the same order at weekly intervals. Sildenafil citrate was given orally 45 minutes before Doppler investigation, and patients had VSS during the waiting period. The patients were asked about their satisfaction and comfort after each test. Statistical analysis was performed using the Wilcoxon and Mann-Whitney U tests. Results. The measurements with papaverine, PGE(1), and sildenafil citrate were significantly different from those after only VSS (P < 0.008); however, the papaverine, PGE(1), and sildenafil citrate results were not different from each other according to the peak systolic velocity, end-diastolic velocity, and resistance index measurements (P > 0.008). Patients commented that although PGE(1) was the strongest erectogenic agent, sildenafil citrate was the most convenient. Conclusions. Since the results of PDU with oral sildenafil citrate in association with VSS were not statistically different, we suggest a new noninvasive erection induction method for the purpose of PDU evaluation of erectile dysfunction. UROLOGY 57: 623-627, 2001. (C) 2001, Elsevier Science Inc.Öğe Sildenafil citrate for penile hemodynamic determination: An alternative to intracavernosal agents in Doppler ultrasound evaluation of erectile dysfunction - Reply (editorial material)(Elsevier Science Inc, 2001) Basar, M.M.; Batislam, E.; Altinok, D.; Yilmaz, E.; Basar, H.…Öğe Sildenafil itself can not be a possible cause of non-arteritic ischemic optic neuropathy(Wiley-Blackwell Publishing, Inc, 2004) Taner, P.; Basar, M. M.; Bilgili, M. Y.; Ergin, A.; Batislam, E.…Öğe Two clinical problems in elderly men: Osteoporosis and erectile dysfunction(Taylor & Francis Inc, 2005) Keleş, Işık; Aydın, Gülümser; Orkun, S.; Basar, M. Murad; Batislam, E.Seventy-six of 108 random men aged 50 years or over were evaluated for erectile dysfunction with interviews of patients using the International Index of Erectile Function Form and minimal evaluation. Serum hormone concentrations were measured. Bone mineral density was measured using dual energy x-ray absorptiometry. Hormone levels did not show significance in terms of erectile dysfunction or bone mineral density results. Erectile dysfunction was determined in 57 (75%) of 76 palients. Ten (13.2%) patients had osteoporosis and 45 (59.2%) had osteopenia at the bone mineral density measurements. The distribution of bone mineral density groups relating to erectile dysfunction did not show significance. The frequencies of osteoporosis and erectile dysfunction increased with age, but the association of these conditions seems to be independent of each other and hormonal changes appear not to be the major determinants for both conditions in elderly men.
