Yazar "Ceylan, Ebubekir" seçeneğine göre listele

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    Alterations in serum thiol-disulfiide homeostasis and ischemiamodifiied albumin concentrations in clinical canine parvoviral enteritis
    (Tubitak Scientific & Technological Research Council Turkey, 2024) Şenel, Yasin; Terzi, Osman Safa; Kara, Erdal; Erel, Özcan; Neşelioğlu, Salim; Ceylan, Ebubekir
    Monitoring biomarkers related to inflammation and oxidative stress is critical in dogs because parvovirus causes both inflammatory and antioxidant alterations. The aim of this study was to investigate inflammatory and antioxidant changes caused by canine parvoviral enteritis to better understand the oxidative stress process related to this disease. Thus, the total thiol, native thiol, disulfide, and ischemia-modified albumin levels of Canine parvovirus infected symptomatic puppies and healthy puppies were examined. Using the results of complete blood counts, the blood serum thiol-disulfide homeostasis and ischemia modified albumin levels of the puppies with Canine parvoviral enteritis (n = 65) and the healthy puppies (n = 34) were compared. Canine parvoviral enteritis and control groups showed a statistically significant difference in thiol disulfide levels (p < 0.01), while no significant difference was observed in ischemia modified albumin levels between the two groups. As a result of this study, a picture contradictory to the literature information was discovered; it is believed that integrating research on oxidative stress at various stages of disease progression, including the early stage, clinical period and recovery processes may provide more information about the dynamics of oxidative stress during disease progression.
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    Öğe
    Dynamic thiol-disulphide homeostasis and ischemia modified albumin levels in neonatal calf diarrhea
    (Ankara Univ, 2023) Terzi, Osman Safa; Kara, Erdal; Senel, Yasin; Ceylan, Ebubekir; Neselioglu, Salim; Erel, Ozcan
    The aim of this study was to determine dynamic thiol-disulphide homeostasis (TDH) parameters and ischemia modified albumin (IMA) levels in calves with neonatal diarrhea and compare with healthy controls. A total of 50 calves were included in the study. There were 25 calves in both diarrhea and healthy groups. Serum native thiol, total thiol, disulfide and IMA levels were measured using new methods. Native thiol (P=0.025) and total thiol (P=0.041) values decreased significantly in calves with neonatal diarrhea compared to the healthy control group. Disulphide (P=0.133), disulphide/native thiol ratio (P=0.001) and IMA (P=0.0018) parameters were lower in healthy group, and the difference between the two groups was significant for the parameters other than disulphide. This study shows that TDH is impaired in neonatal calf diarrhea and IMA levels are increased due to oxidative stress.
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    Öğe
    Failure of passive transfer in neonatal calves in dairy farms in Ankara region
    (2021) Kara, Erdal; Ceylan, Ebubekir
    This study, as a model for the farms in Turkey implementing professional herd management protocols, was conducted to\rexamine a variety of factors in relation to the prevalence of failure of passive transfer (FPT) and the passive transfer (PT) in dairy farms\rin Ankara. A total of 400 calves and 363 cows from 9 different farms practicing professional herd management systems and employ\rfull-time veterinarians were included in the study. Following the birth of the calf, colostrum was taken from cows, blood samples were\rtaken from calves at 24–48 h of age and analysed for IgG using ELISA. FPT was determined in 69 (17.25%) of 400 calves examined and\r44 (12.12%) of 363 cows produced insufficient quality colostrum (IgG concentration ? 50 mg/mL). The average blood IgG concentration\rof calves was 14.16 mg/mL, and the average colostrum IgG concentration was 90.41 mg/mL. When various data related to FPT are\revaluated, the risk of FPT increases 15.4 times in calves fed with insufficient quality colostrum, and the risk of overcoming diseases\rin calves with FPT increases 1.6 times until weaning. In conclusion, the FPT rate was around 20% in dairy farms in Ankara, where\radvanced herd management techniques were practiced and still pose a serious risk.
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    Öğe
    Failure of passive transfer in neonatal calves in dairy farms in Ankara region
    (Tubitak Scientific & Technological Research Council Turkey, 2021) Kara, Erdal; Ceylan, Ebubekir
    This study, as a model for the farms in Turkey implementing professional herd management protocols, was conducted to examine a variety of factors in relation to the prevalence of failure of passive transfer (FPT) and the passive transfer (PT) in dairy farms in Ankara. A total of 400 calves and 363 cows from 9 different farms practicing professional herd management systems and employ full-time veterinarians were included in the study. Following the birth of the calf, colostrum was taken from cows, blood samples were taken from calves at 24-48 h of age and analysed for IgG using ELISA. FPT was determined in 69 (17.25%) of 400 calves examined and 44 (12.12%) of 363 cows produced insufficient quality colostrum (IgG concentration. 50 mg/mL). The average blood IgG concentration of calves was 14.16 mg/mL, and the average colostrum IgG concentration was 90.41 mg/mL. When various data related to FPT are evaluated, the risk of FPT increases 15.4 times in calves fed with insufficient quality colostrum, and the risk of overcoming diseases in calves with FPT increases 1.6 times until weaning. In conclusion, the FPT rate was around 20% in dairy farms in Ankara, where advanced herd management techniques were practiced and still pose a serious risk.
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    Öğe
    Yerli Kara ve İsviçre Esmeri Irkı Sığırların Kolostrum Kalitesinin Karşılaştırılması
    (2020) Kara, Erdal; Terzi, Osman Safa; Şenel, Yasin; Ceylan, Ebubekir
    Ruminant plasentaları sindesmokoryal tipte olduğu için maternal sirkülasyonla yavru sirkülasyonubirbirinden ayrılmaktadır. Bu sebeple yenidoğan buzağılar neonatal dönem olarak da isimlendirilendoğumu takiben ilk 28 günlük periyotta, annelerinin kolostrumundan alacakları bağışıklıkbileşenlerine ihtiyaç duyarlar. Pasif immun transfer başarısı için toplam kolostralImmunlobülinlerinlerin %85-90’ını oluşturan Immunglobülin G’nin kolostrumdaki miktarı kalitenoktasında belirleyicidir. Çalışmanın amacı; yerli gen kaynaklarımızdan olan Yerli Kara ırkı sığırlarile kombine verimli bir kültür ırkı olan İsviçre Esmeri’nin kolostrum kalitelerinin karşılaştırılmasıdır.Çalışmanın hayvan materyalini 40 saf Yerli Kara sığır ve 39 saf İsviçre Esmeri sığır oluşturdu.Kolostrum Immunglobulin G seviyesi ELISA yöntemi kullanılarak belirlendi. Yerli Kara ve İsviçreEsmeri sığırların tanımlayıcı istatistik verilerine göre ortalama Immunglobulin G konsantrasyonlarısırasıyla; 133.1±77.28 mg/mL, 74.60±28.44 mg/mL olduğu tespit edildi. İki grup arasındakiImmunglobulin G verileri bağımsız t testi ile karşılaştırıldığında istatistiksel olarak önemli olduğutespit edildi (P<0.001). Sonuç olarak; bu çalışmayla Yerli Kara ırkının kolostrum kalitesinin sütüretimi yüksek olan İsviçre Esmeri ırkına oranla oldukça yüksek olduğu görüldü.