Dynamic thiol-disulphide homeostasis and ischemia modified albumin levels in neonatal calf diarrhea

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Tarih

2023

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Ankara Univ

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

The aim of this study was to determine dynamic thiol-disulphide homeostasis (TDH) parameters and ischemia modified albumin (IMA) levels in calves with neonatal diarrhea and compare with healthy controls. A total of 50 calves were included in the study. There were 25 calves in both diarrhea and healthy groups. Serum native thiol, total thiol, disulfide and IMA levels were measured using new methods. Native thiol (P=0.025) and total thiol (P=0.041) values decreased significantly in calves with neonatal diarrhea compared to the healthy control group. Disulphide (P=0.133), disulphide/native thiol ratio (P=0.001) and IMA (P=0.0018) parameters were lower in healthy group, and the difference between the two groups was significant for the parameters other than disulphide. This study shows that TDH is impaired in neonatal calf diarrhea and IMA levels are increased due to oxidative stress.

Açıklama

Anahtar Kelimeler

Dynamic thiol-disulphide homeostasis; Ischemia modified albumin; Neonatal calf diarrhea; Oxidative stress

Kaynak

Ankara Universitesi Veteriner Fakultesi Dergisi

WoS Q Değeri

Q3

Scopus Q Değeri

Q3

Cilt

70

Sayı

1

Künye