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Öğe Helicobacter pylori seropositivity and atherosclerosis risk factors(Karger, 2004) Köksal, A.; Ekmekci, Y.; Karadeniz, Y.; Köklü, S.; Apan, T.; Yilmaz, M.; Yildiz, A.Certain viral and bacterial infections may contribute to the initiation and progression of atherosclerosis. The aim of this study is to determine whether Helicobacter pylori ( HP) seropositivity contributes to conventional atherosclerosis risk factors in the development of an early sign of atherosclerosis: intima-media thickness (IMT) of the carotid artery. Eighty-four patients who had at least two conventional atherosclerosis risk factors and a control group of 50 patients having no risk factors for atherosclerosis were enrolled in the study. None of the patients had ever received HP eradication treatment. HP IgG antibodies were determined by enzyme-linked immunosorbent assay. Carotid artery IMT was measured 1 cm before the carotid bifurcation. Seventy-five percent of the study group was HP seropositive. HP seropositive ( n = 64) and seronegative ( n = 21) groups were identical in terms of sex distribution, smoking pattern, mean age, hemoglobin, leukocyte, platelet, C-reactive protein, erythrocyte sedimentation rate, glucose, cholesterol, triglyceride, low-density lipoprotein, high-density lipoprotein, systolic blood pressure and diastolic blood pressure levels. There was no significant difference between the mean carotid IMT of HP seropositive (0.8 +/- 0.3 mm) and negative ( 0.8 +/- 8 0.3 mm) patients in the study group. Similar to the study group, there was no statistically significant difference between mean carotid IMT of HP seropositive (0.56 +/- 0.19 mm) and negative patients (0.67 +/- 0.13 mm) in the control group ( p = 0.2). Future studies concerning virulent strains are needed to determine the probable role of HP in atherosclerosis. Copyright (C) 2004 S. Karger AG, Basel.Öğe Magnetic resonance imaging of the intratemporal facial nerve in idiopathic peripheral facial palsy(Elsevier Science Inc, 2003) Yetiser, S.; Kazkayas, M.; Altinok, D.; Karadeniz, Y.The aim of this study was to investigate the prevalence of facial nerve involvement with gadolinium-enhanced magnetic resonance imaging (Gd-MRI) in patients with idiopathic peripheral facial palsy (IPFP), and to discuss the localization and the pattern of enhancement. A total of 13 patients (9 female, 4 male) with IFPF were included in this study. Topographic tests and electromyography (EMG) were performed, and MRI was taken. Ten subjects whose cranial MRIs were taken for nonorganic pathology served as the control group. Twelve of 13 paralytic facial nerves had enhancement on postcontrast images. Two facial nerves of the control group demonstrated enhancement. We found a correlation between the enhancement of the facial nerve and the time for recovery. The average time from the onset of facial palsy to the recovery in patients with enhancement was 14 weeks, whereas it was 6 weeks in patient with no enhancement. Finally, all patients had complete recovery of the facial nerve function. We concluded that contrast enhancement of the paralytic facial nerve can be a radiological sign of a neural inflammation and may indicate a prolonged recovery. (C) 2003 Elsevier Science Inc. All rights reserved.Öğe De novo translocation t(5;6)(q35;q21) in an infant with Walker-Warburg syndrome(Wiley-Liss, 2002) Karadeniz, N.; Zenciroğlu, A.; Gürer, Y.K.Y.; Senbil, N.; Karadeniz, Y.; Topaloğlu, H.…Öğe Perception of bronchoconstriction in obstructive pulmonary diseases (disease-specific dyspnoea)(Portland Press Ltd, 2003) Ekici, A.; Yilmaz, S.; Ekici, M.; Kalpaklioglu, F.; Karadeniz, Y.; Arslan, M.; Kurtipek, E.The perception of dyspnoea differs between subjects with obstructive pulmonary diseases, partly because the underlying mechanisms for bronchoconstriction are different. We investigated the perception of bronchoconstriction in subjects with bronchiectasis, asthma and chronic bronchitis and possible contributing factors. Forty-seven non-smoking subjects with bronchiectasis, 50 subjects with asthma and 31 with chronic bronchitis were challenged with histamine. The Borg score was assessed before and after each challenge. The perception score corresponding to a fall in the forced expiratory volume in 1 s (FEV1)by 20% (PS20) was calculated. The mean values of DeltaBorg/DeltaFEV(1), (the Borg score change divided by the change in FEV1 as a percentage of the baseline FEV1) and PS20 of subjects with bronchiectasis and chronic bronchitis were significantly lower than in subjects with asthma after histamine challenge. The ratio of non-perceivers was higher in bronchiectasis (25.5%) and in chronic bronchitis (32.3%) than in asthma (4.0%). When all subjects were considered, DeltaBorg/DeltaFEV, values were significantly related to female sex(r(2)=11.5%, P=0.0001), but not to age, duration of the disease, PD20 or baseline FEV1%. The present study indicates that perception of histamine-induced bronchoconstriction is lower in patients with bronchiectasis and chronic bronchitis than in asthmatic patients, and that sex partially contributes to this difference.Öğe Resistance index in fetal interlobar renal artery with renal pelvic dilatation up to 10 MM(John Wiley & Sons Inc, 2003) Kara, S.A.; Noyan, V.; Karadeniz, Y.; Yücel, A.; Altinok, D.; Bayram, M.Purpose. The purpose of this study was to compare the resistance indices (RIs) in the fetal interlobar renal arteries (IRAs) of third-trimester fetuses with or without pelvicaliceal dilatation of up to 10 mm and to compare them with those of the full-term healthy infants. Methods. Women with uncomplicated, low-risk, singleton third-trimester pregnancies were examined sonographically. The RIs in the IRAs were measured in the fetuses, who were stratified into 3 groups according to the anteroposterior diameter of the renal pelvic dilatation: group I, no dilatation; group II, 1-5-mm dilatation, and group III, 6-10-mm dilatation. Results. In total, 178 women were examined. We could study both kidneys in 139 of the fetuses; in the other 39, only 1 kidney could be imaged perfectly. This yielded a total of 317 kidneys. Group I fetuses included 172 (54%); group II, 98 (31%); and group III, 47 (15%) of the kidneys. The mean ( standard deviation) RIs in the IRAs were 0.81 +/- 0.09, 0.80 +/- 0.07, and 0.80 +/- 0.06 in the 3 groups, respectively, with no statistically significant difference between the groups (p = 0.72). There was also no statistically significant difference between the RIs recorded in the right and left kidneys. The mean RI in the IRAs of the 34 infants who were available for follow-up 6-12 weeks after delivery was 0.73 +/- 0.07, which was significantly less than that recorded in the third-trimester fetuses (P = 0.005). Conclusions. The RI in the fetal IRA does not differ in fetuses with and without renal pelvic dilatation of up to 10 mm. Thus, an increase in the RI or an RI that significantly differs between the right and left kidneys should be investigated further for possible renal pathology. (C) 2003 Wiley Periodicals, Inc.
