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Öğe Malondialdehyde levels and total antioxidant capacity in the dental follicles of the asymptomatic impacted third molars(Cumhuriyet University Faculty of Dentistry, 2015) Tekin U.; Kisa U.; Atil F.; Hendek M.K.; Dogan O.; Gurcan S.Objectives: Malondialdehyde (MDA), is one of many low molecular weight end products of lipid peroxidation (LPO), increases in oxidative stress. Antioxidants such as total antioxidant capacity (TAC) have a protective effect against reactive oxygen species. The aim of this study is to examine the development of the antioxidant defense mechanism in dental follicles (DFs) of radiologically asymptomatic impacted third molars (ITMs) by using MDA and TAC. Materials and Methods: This study involved 40 DFs of 40 patients referred for clinically and radiographically asymptomatic ITMs. 40 healthy gingival tissues in the same patients obtained during surgical removal of teeth as a control group. This study involved DFs widths on periapical radiographs narrower than 2.5 mm were included in the study. All of tissues samples were analyzed for MDA and TAC. Results: Levels of the MDA and TAC in DFs were significantly higher than the levels of MDA and TAC provided from healthy gingival tissues of the same patients (p<0.05). Conclusions: The results of our study showed that an important antioxidant defense mechanism may also occur in DFs of asymptomatic ITMs. In the light of these preliminary findings of the presented study, supplementary studies should be undertaken to establish the differences between inflammation affecting the DFs and clinical outcomes.Öğe Viburnum opulus: could it be a new alternative, such as lemon juice, to pharmacological therapy in hypocitraturic stone patients?(2014) Tuglu D.; Yılmaz E.; Yuvanc E.; Erguder I.; Kisa U.; Bal F.; Batislam E.OBJECTIVE: Citrate, potassium, and calcium levels in Viburnum opulus (V. opulus) and lemon juice were compared to evaluate the usability of V. opulus in mild to moderate level hypocitraturic stone disease.MATERIALS AND METHODS: V. opulus and lemon fruits were squeezed in a blender and 10 samples of each of 100 ml were prepared. Citrate, calcium, sodium, potassium, magnesium, and pH levels in these samples were examined.RESULTS: Potassium was found to be statistically significantly higher in V. opulus than that in lemon juice (p = 0.006) whereas sodium (p = 0.004) and calcium (p = 0.008) were found to be lower. There was no difference between them in terms of the amount of magnesium and citrate.CONCUSIONS: Because V. opulus contains citrate as high as lemon juice does and it is a potassium-rich and calciumand sodium-poor fluid, it can be an alternative to pharmaceutical treatment in mild-to-moderate degree hypocitraturic stone patients. These findings should be supported with clinical studies.