Malondialdehyde levels and total antioxidant capacity in the dental follicles of the asymptomatic impacted third molars
Yükleniyor...
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Cumhuriyet University Faculty of Dentistry
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objectives: Malondialdehyde (MDA), is one of many low molecular weight end products of lipid peroxidation (LPO), increases in oxidative stress. Antioxidants such as total antioxidant capacity (TAC) have a protective effect against reactive oxygen species. The aim of this study is to examine the development of the antioxidant defense mechanism in dental follicles (DFs) of radiologically asymptomatic impacted third molars (ITMs) by using MDA and TAC. Materials and Methods: This study involved 40 DFs of 40 patients referred for clinically and radiographically asymptomatic ITMs. 40 healthy gingival tissues in the same patients obtained during surgical removal of teeth as a control group. This study involved DFs widths on periapical radiographs narrower than 2.5 mm were included in the study. All of tissues samples were analyzed for MDA and TAC. Results: Levels of the MDA and TAC in DFs were significantly higher than the levels of MDA and TAC provided from healthy gingival tissues of the same patients (p<0.05). Conclusions: The results of our study showed that an important antioxidant defense mechanism may also occur in DFs of asymptomatic ITMs. In the light of these preliminary findings of the presented study, supplementary studies should be undertaken to establish the differences between inflammation affecting the DFs and clinical outcomes.
Açıklama
Anahtar Kelimeler
Dental follicle, Malondialdehyde, Oral mucosa, Total antioxidant capacity
Kaynak
Cumhuriyet Dental Journal
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
18
Sayı
2
Künye
Tekin, U., Kısa, Ü., Atıl, F., Karşıyaka, M. H., Doğan, Ö., Gürcan, S. (2015). Malondialdehyde levels and total antioxidant capacity in the dental follicles of the asymptomatic impacted third molars. Cumhuriyet Dental Journal , 18(2), 108 - 115.
