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Öğe Change in retrobulbar circulation during menstrual cycle assessed by Doppler ultrasound(Elsevier Science Inc, 2002) Karadeniz, M.Y.; Yücel, A.; Kara, S.A.; Noyan, V.; Altinok, D.; Ergin, A.; Güney, S.Our purpose was to study the hemodynamic changes in the ophthalmic, central retinal and posterior ciliary arteries during the normal menstrual cycle and to relate the vascular changes to menstrual cycle. A total of 23 healthy women underwent serial color Doppler ultrasonography at least six times during a normal menstrual cycle, twice each in follicular, ovulatory and luteal phases. Pulsatility and resistance index and peak systolic velocity of the each arteries were assessed with color Doppler imaging. There was no statistical difference in any of the parameters during the menstrual cycle. This was supposed to be because generalized hormonal effects on heart rate, blood pressure, blood volume, cardiac output and on the diameter of the vessel cancel each other and this effect maintains the same ocular blood flow and perfusion during the menstrual cycle. (E-mail: mykaradeniz@hotmai.com) (C) 2002 World Federation for Ultrasound in Medicine Biology.Öğe Comparison of microlaparoscopy and conventional laparoscopy for tubal sterilization under local anesthesia with mild sedation(Journal Amer Assoc Gynecologic Laparoscopists, 2001) Tiras, MB; Gökçe, O.; Noyan, V.; Zeyneloglu, H.B.; Güner, H.; Yildirim, M.; Risquez, F.Study Objective. To compare tubal sterilization performed by microlaparoscopy and conventional laparoscopy. Design. Prospective, randomized trial (Canadian Task Force classification 1). Setting. Gazi University School of Medicine. Patients. Twenty women undergoing surgical sterilization. Intervention. Ten sterilizations by conventional laparoscopy and 10 by microlaparoscopy. Measurements and Main Results. The techniques were comparable in quality of visualization, operating time, amount of drugs used for sedation and local anesthesia, and intraoperative pain scores. However, the postoperative analgesic requirement was significantly less in women treated by by microlaparoscopy. Conclusion. Tubal sterilization by microlaparoscopy does not differ greatly from conventional laparoscopic sterilization.Öğe Cytotoxin associated gene A-positive Helicobacter pylori strains in dyspeptic pregnant women(Elsevier Sci Ireland Ltd, 2004) Noyan, V.; Apan, T.Z.; Yücel, A.; Sağsöz, N.Objective: The aim of the present study was to compare the Helicobacter pylori (HP) seropositivity and cytotoxin associated gene A (cagA) status in pregnant women with dyspeptic complaints and pregnant women with no gastrointestinal symptoms. Study design: Seventy-one consecutive pregnant women with gastrointestinal complaints and 72 age-matched pregnant women without any gastrointestinal symptoms or a history of gastrointestinal disease were included in the study. Demographic characteristics and H. pylori and cytotoxin associated gene A status of the groups were analysed. Results: The prevalence of H. pylori seropositivity was slightly but not significantly higher in patients with dyspeptic complaints compared to the controls (74.6% versus 63.8%, respectively, P > 0.05). The incidence of dyspeptic complaints were 53.5% in HP-seropositive and 40.9% in HP-seronegative women (P > 0.05). The prevalence of cytotoxin associated gene A positivity among H. pylori-seropositive women was significantly higher in dyspeptic pregnants compared to the controls (75.5% versus 45.7%, respectively, P = 0.002). Among HP-seropositive women, the incidence of dyspeptic complaints was significantly higher in cagA-positive patients compared to the cagA-negative ones (65.6% versus 34.2%, respectively, P = 0.002). When analysed according to the trimesters, the prevalence of cytotoxin associated gene A positivity among H. pylori-seropositive women was significantly higher in dyspeptic pregnants compared to the controls in the first trimester (68.0% versus 34.8%, respectively, P = 0.021). Conclusion: Cytotoxin associated gene A-positive, virulant H. pylori strains were found to be more frequently associated with dyspeptic complaints in pregnant women. (C) 2004 Elsevier Ireland Ltd. All rights reserved.Öğe Effects of a monthly injectable steroidal contraceptive, Mesigyna, on menstrual pattern, lipoproteins, and coagulation parameters(Elsevier Science Inc, 2001) Tiras, M.B.; Noyan, V.; Fener, N.; Guner, H.; Yildirim, M.; Darney, P.D.The objective of this study was to determine the effects of a once-monthly injectable contraceptive (Mesigyna) on menstrual pattern, lipoproteins, and coagulation parameters. Thirty-six women aged 18-35 years requesting monthly injectable contraception were included. Before injecting estradiol valerate 5 mg and norethisterone enanthate 50 mg, coagulation, lipoprotein, and liver function parameters were determined. After the 3- and 6-month injections, the same coagulation and serum lipid measurements and liver function tests were repeated, and women were questioned about their menstrual patterns and side effects. Thirty women who completed 6 months were evaluated. At the end of 3 months, two-thirds of the 30 women had normal menstrual patterns; at the end of 6 months, 80% of the women had normal menses. Serum LDL, total cholesterol, and triglyceride levels did not change significantly, while HDL and VLDL decreased significantly (p = 0.032 and p = 0.039, respectively) at 6 months. PT and aPTT measures did not change at the end of 6 months, while fibrinogen levels were significantly lower (p = 0.013). Serum total bilirubin levels increased (p = 0.022) and albumin levels decreased (p = 0.022) at the end of 6 months. Mesigyna was well tolerated and side effects and menstrual abnormalities were acceptable. There were no clinically significant changes in lipoprotein, coagulation, or hepatic parameters. (C) 2001 Elsevier Science Inc. All rights reserved.Öğe Ovarian wedge resection by minilaparatomy in infertile patients with polycystic ovarian syndrome: a new technique(Elsevier Sci Ireland Ltd, 2003) Yildirim, M.; Noyan, V.; Tiras, M.B.; Yildiz, A.; Guner, H.Objective: To determine the effects of ovarian wedge resection by minilaparotomy in infertile patients with polycystic ovarian syndrome (PCOS). Study design: One hundred and thirty-four anovulatory patients with PCOS, who were previously treated with clomiphene citrate and gonadotropins and did not concieve were operated via minilaparotomy with microsurgical principles and ovarian wedge resection was performed on each subject. Pregnancy rates and adhesion formation were investigated retrospectively. Results: A total of 121 pregnancies were achieved in 2 years (90%). One hundred and four patients concieved within the first 6 months (78%) and the remaining 17 patients concieved within 2 years (13%) following the operation. Sixty-eight patients had a second pregnancy later. In the post-operative period, 24 patients had cesarean delivery and 20 had diagnostic laparoscopy. Out of these 44 patients, only 5 of them were found to have minimal adhesions. Conclusion: This technique offers high pregnancy rates and minimal adhesion formation. Ovarian wedge resection by minilaparotomy might be an alternative treatment approach in patients with PCOS who did not concieve with standart ovulation induction protocols. (C) 2002 Published by Elsevier Science Ireland Ltd.Öğe Resistance index in fetal interlobar renal artery with renal pelvic dilatation up to 10 MM(John Wiley & Sons Inc, 2003) Kara, S.A.; Noyan, V.; Karadeniz, Y.; Yücel, A.; Altinok, D.; Bayram, M.Purpose. The purpose of this study was to compare the resistance indices (RIs) in the fetal interlobar renal arteries (IRAs) of third-trimester fetuses with or without pelvicaliceal dilatation of up to 10 mm and to compare them with those of the full-term healthy infants. Methods. Women with uncomplicated, low-risk, singleton third-trimester pregnancies were examined sonographically. The RIs in the IRAs were measured in the fetuses, who were stratified into 3 groups according to the anteroposterior diameter of the renal pelvic dilatation: group I, no dilatation; group II, 1-5-mm dilatation, and group III, 6-10-mm dilatation. Results. In total, 178 women were examined. We could study both kidneys in 139 of the fetuses; in the other 39, only 1 kidney could be imaged perfectly. This yielded a total of 317 kidneys. Group I fetuses included 172 (54%); group II, 98 (31%); and group III, 47 (15%) of the kidneys. The mean ( standard deviation) RIs in the IRAs were 0.81 +/- 0.09, 0.80 +/- 0.07, and 0.80 +/- 0.06 in the 3 groups, respectively, with no statistically significant difference between the groups (p = 0.72). There was also no statistically significant difference between the RIs recorded in the right and left kidneys. The mean RI in the IRAs of the 34 infants who were available for follow-up 6-12 weeks after delivery was 0.73 +/- 0.07, which was significantly less than that recorded in the third-trimester fetuses (P = 0.005). Conclusions. The RI in the fetal IRA does not differ in fetuses with and without renal pelvic dilatation of up to 10 mm. Thus, an increase in the RI or an RI that significantly differs between the right and left kidneys should be investigated further for possible renal pathology. (C) 2003 Wiley Periodicals, Inc.
