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    Effects of boric acid on experimental periodontitis and alveolar bone loss in rats
    (Pergamon-Elsevier Science Ltd, 2012) Demirer, Serhat; Kara, M. Isa; Erciyas, Kamile; Ozdemir, Hakan; Ozer, Hatice; Ay, Sinan
    Objective: The goal of the present study was to evaluate the histopathologic and morphometric effects of systemic boric acid in a rat periodontitis model. Design: Twenty-four Wistar rats were divided into three groups of eight animals each: non-ligated (NL), ligature only (LO), and ligature and treated with boric acid (BA) (3 mg/kg per day for 11 days). A 4/0 silk suture was placed in a subgingival position around the mandibular first molars; after 11 days the rats were sacrificed, and changes in alveolar bone levels were measured clinically and tissues were histopathologically examined to assess the differences amongst the study groups. Results: The ratio of presence of inflammatory cell infiltration (ICI) and osteoclast number in the LO group was significantly higher than that of the NL and BA groups (p < 0.05). The ratio of presence of osteoblastic activity in the LO group was significantly lower than that of the NL and BA groups (p < 0.05). Alveolar bone loss was also significantly higher in the LO group compared to the BA and NL groups (p < 005). Conclusions: This study has demonstrated that systemic administration of boric acid reduced periodontal inflammation and alveolar bone loss in periodontal disease in rats. (C) 2011 Elsevier Ltd. All rights reserved.
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    Effects of Orthodontic Treatment on Patients' Dental Anxiety and Oral Health Knowledge
    (Aves Press Ltd, 2009) Ozturk, Firat; Sokucu, Oral; Demirer, Serhat; Nalcaci, Ruhi; Ozdemir, Hakan
    The aim of this study was to investigate effects of orthodontic treatment on both anxiety and oral health knowledge of orthodontic patients. The study was carried out in 184 patients. Four groups were formed according to the stage of orthodontic treatment. Group 1 consisted of 47 individuals selected from patients who were awaiting orthodontic treatment; groups 2 and 3, comprised 44 and 46 individuals who had been undergoing orthodontic treatment for a period of 1-12 and 12-26 months respectively, and group 4, 47 orthodontically treated individuals. The modified Dental Anxiety Scale was used to measure dental anxiety. Oral health knowledge was assessed using several questions concerning etiology, symptoms and prevention. Chi-squire test was used for statistical assessment. The anxiety level of patients in group 1 was significantly higher than the subjects in group 4. Patients in groups 2, 3 and 4 mostly knew that gum bleeding is a sign of periodontal disease (81.8, 84.7, 80.1 per cent respectively); and this was 63.8 per cent for group 1. Patients in all groups were aware how to prevent, however those who were undergoing or had completed treatment were more informed about symptoms of periodontal disease. Only 19.6 and 52.1 per cent of subjects in group 3 had the knowledge to identify dental plaque and what it can cause respectively; which was the highest ratio among the groups. Orthodontic treatment involves some degree of exposure, consequently creates a positive influence on patients' anxiety and periodontal health knowledge.
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    Periodontal Healing of Marginal Flap Versus Paramarginal Flap in Palatally Impacted Canine Surgery: A Prospective Study
    (W B Saunders Co-Elsevier Inc, 2009) Kosger, Hueseyin; Polat, Hidayet B.; Demirer, Serhat; Ozdemir, Hakan; Ay, Sinan
    Purpose: The aim of the present study was to compare the influence of 2 mucoperiosteal flaps, marginal and paramarginal, on the periodontal healing of adjacent maxillary teeth after extraction of palatally impacted canines. Patients and Methods: Marginal (15 patients) and paramarginal (16 patients) techniques were used to remove palatally impacted canines. The periodontal examination of the adjacent teeth included evaluation of the plaque index, gingival index, probing depth, and clinical crown length preoperatively and at the first, third, and sixth months postoperatively using an individual acrylic stent. Results: No significant differences between the marginal and paramarginal flaps were found with respect to plaque index, gingival index, labial and palatal probing depth, and labial and palatal clinical crown length at all follow-up points. Conclusion: The results of our study have shown that the paramarginal flap design is a good alternative to the marginal flap design. (C) 2009 American Association of Oral and Maxillofacial Surgeons J Oral Maxillofac Surg 67: 1826-1831, 2009