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  • Küçük Resim
    Öğe
    Association of asthma-related symptoms with snoring and apnea and effect on health-related quality of life
    (Elsevier, 2005) Ekici, Aynur; Ekici, Mehmet; Kurtipek, Ercan; Keleş, Hatice; Kara, Türkan; Tunçkol, Müge; Koçyiğit, Pınar
    Objectives: This study aimed to investigate the association of asthma-related symptoms with snoring and apnea, and to assess their effects on health-related quality of life (HRQL). Design: Population-based cross-sectional study. Subjects and methods: A total of 10,224 parents and grandparents of students from 14 randomly selected primary schools in city center were asked to answer questionnaires sent by their children. All subjects were questioned for asthma-related symptoms, sleep-related disorders (snoring and apnea), and for HRQL using the Respiratory Questionnaire, Sleep and Health Questionnaire, and Short Form-12 (SF-12) Health Survey, respectively. Results: The overall response rate to questionnaires was 97.7%, and all analysis was performed on 7,469 subjects (3,920 women and 3,549 men) who provided sufficient responses to questions. There were 2,713 subjects who reported asthma-related symptoms. The snoring and the observed apnea were more prevalent in subjects with asthma-related symptoms (54.0% vs 41.4%; odds ratio [OR], 1.7; 95% confidence interval [CI], 1.5 to 1.8; p < 0.001) than those without asthma-related symptoms (16.7% vs 7.0%; OR, 2.7; 95% CI, 2.3 to 3.1; p < 0.001), respectively. Asthma-related symptoms were found to be associated with snoring (OR, 1.5; 95% CI, 1.3 to 1.6; p < 0.001) and observed apnea (OR, 2.2; 95% CI, 1.8 to 2.5; p < 0.001) after adjusting for gender, age, body mass index, income, education, and smoking. Also, HRQL was found to be adversely affected by asthma-related symptoms, snoring, and observed apnea (beta = - 0.26, p < 0.001; beta = - 0.07, p < 0.001; and beta = - 0.08, p < 0.001, respectively, for SF-12 overall score) after adjusting for other confounding factors. Conclusion: Present data suggest that there is a link between the sleep-related breathing disorders and asthma-related symptoms. Moreover, the presence of snoring and observed apnea in individuals with asthma-related symptoms causes further impairment in HRQL. The effects on HRQL of coexistence of these three disorders should be supported by clinical studies.
  • Küçük Resim
    Öğe
    Effect of psychological on respiratory symptoms
    (2005) Ekici, Aydanur; Oğuztürk, Ömer; Ekici, Mehmet; Kurtipek, Ercan; Akın, Ahmet; Arslan, Mesut; Tunçkol, Müge
    Amaç: Psikolojik durumun solunum semptomu bildirmeye ve solunum sisteminin objektif ölçümlerine etkisinin olup olmadığını araştırdık. Materyal ve Metotlar: Çalışmaya silah fabrikasında çalışan 1090 erkek işçi ve biomasse maruz kalan 420 kadın alındı. Olgular respiratuar sorgulama formu ile sorgulanarak portable spirometre cihazı ile solunum fonksiyonları ölçüldü.Psikolojik durum HAD scalası ile ölçülerek ;median değere göre yüksek ve düşük HAD total skorlu gruplar olarak sınıflandırıldılar. Bulgular: Erkeklerde: Kronik öksürük (%17,6 vs %10,7 p0,001), Kronik balgam (13,2% vs.8,9%, p0,02) ve muhtemel astım (%39,5 vs %25,5, p0,0001) yüksek HAD total skorlu grupta düşük HAD total skorlu grupa göre önemli olarak daha sık bulunurken kesin astım (%6,2 vs %4,6, p0,2) için gruplar arasında fark yoktu. Kadınlarda: Kronik öksürük (%34,8 vs %23,5 p0,009), kronik balgam (%23,9 vs. %15,4, p0,02) ve muhtemel astım (%53,5 vs %35,3, p0,0001) yüksek HAD total skorlu grupta düşük HAD total skorlu grupa göre önemli olarak daha sık bulunurken kesin astım (%7,0 vs %9,0, p0,4) için gruplar arasında fark yoktu. Sonuç: Respiratuar sorgulamada semptom bildirme sıklığı psikolojik durumdan etkilenebilir.Respiratuar sorgulama ve psikolojik durum göstergeleri eşzamanlı olarak yorumlanmalıdır.