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Öğe Compass cutter for periareolar incisions(Springer, 2008) Yazici, I.; Cavusoglu, T.; Karakaya, E. I.; Vargel, I.…Öğe Cryogel scaffolds with stem cells for bone tissue engineering: an animal model(Mary Ann Liebert Inc, 2008) Boelgen, N.; Vargel, I.; Cavusoglu, T.; Korkusuz, P.; Guezel, E.; Piskin, E.…Öğe Electrospun spiral-wounded polycaprolactone scaffolds with or without stem cells for cranial bone defects: an animal model(Mary Ann Liebert Inc, 2008) Isoglu, I. A.; Bolgen, N.; Vargel, I.; Cavusoglu, T.; Korkusuz, P.; Guzel, E.; Piskin, E.…Öğe Filling cranial defects in rats: 6 months animal study(Mary Ann Liebert Inc, 2008) Aydin, H. M.; Vargel, I.; Cavusoglu, T.; Korkusuz, P.; Guzel, E.; Piskin, E.[Abstract No tAvailable]Öğe Influence of scaffold composition over invitro osteogenic differentiation of hBMSCs and invivo inflammatory response(Sage Publications Ltd, 2014) Costa-Pinto, Ana R.; Vargel, I.; Tuzlakoglu, K.; Correlo, V. M.; Sol, P. C.; Faria, S.; Neves, Nuno M.To understand the role of chitosan in chitosan-poly(butylene succinate) scaffolds (50% wt), 50%, 25%, and 0% of chitosan were used to produce different scaffolds. These scaffolds were invitro seeded and cultured with human bone marrow stromal cells in osteogenic conditions, revealing that higher percentage of chitosan showed enhanced cell viability over time, adhesion, proliferation, and osteogenic differentiation. Scaffolds were also implanted in cranial defects and iliac submuscular region in Wistar rats, and the results evidenced that chitosan-containing scaffolds displayed mild inflammatory response and good integration with surrounding tissues, showed by connective tissue colonization and the presence of new blood vessels. Scaffolds without chitosan-evidenced necrotic tissue in scaffolds' interior, proving that chitosan exerts a positive effect over cell behavior and displays a milder host inflammatory response invivo.Öğe Lactide-PEG cryostructures with stem cells as tissue engineering scaffolds in reconstruction of cranial bone defects in rat model(Mary Ann Liebert Inc, 2008) Egri, S.; Vargel, I.; Cavusoglu, T.; Korkusuz, P.; Guzel, E.; Uckan, D.; Piskin, E.…
