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Öğe Decreased Serum Adenosine Deaminase Activity Correlated with Clinical Score and Serum Proteins in Calves with Cryptosporidiosis(Zoological Soc Pakistan, 2016) Yarim, Gul Fatma; Yagci, Bugrahan Bekir; Ertekin, Ali; Kazak, FilizThis study was aimed to investigate serum adenosine deaminase (ADA) activity in calves with cryptosporidiosis. Significantly higher serum concentrations of globulin (P<0.01), blood urea nitrogen (P<0.01) and creatinine (P<0.01) were found and significantly lower albumin concentration (P<0.01) and albumin to globulin (A/G) ratio (P<0.001) in calves with cryptosporidiosis compared to healthy calves. Serum adenosine deaminase (ADA) activity was determined as 4.12+/-0.91 U/l; in calves with cryptosporidiosis compared to 10.27+/-1.71 U/l in healthy calves, which was significant at P<0.01 level. Serum ADA was negatively correlated with clinical score (P<0.05), which serum total protein concentration (P<0.05), serum globulin concentration (P<0.01) and serum A/G ratio (P<0.05) were positivity correlated in calves with cryptosporidiosis. From these results we concluded that cryptosporidiosis infection is closely related to low serum ADA activity which correlated with clinical score and serum total protein, globulin and A/G ratio in-calves. The results of the present study indicate possible role of ADA in development and progression of cryptosporidiosis.Öğe THE MILK IGF-2 LEVEL IS POSITIVELY CORRELATED WITH MILK YIELD IN ANATOLIAN WATER BUFFALOES(Int Buffalo Information Ctr, 2023) Guler, Hakan; Yarim, Gul Fatma; Yarim, Murat; Duru, Ozkan; Gokceoglu, AyrisThe aim of this study was to investigate the relationship between milk insulin-like growth factor-2 (IGF-2) concentration and milk yield in Anatolian water buffaloes. This study was conducted on milk samples from 80 Anatolian water buffaloes. Milk samples collected from buffaloes were evaluated for subclinical mastitis. For this purpose, the California mastitis test and somatic cell count were performed in milk samples taken from four different mammary lobes of buffaloes. The milk IGF-2 level was determined by an enzyme-linked immunosorbent assay kit. Milk IGF-2 concentration ranged from 21.6 ng/ml -63.2 ng/ml in Anatolian water buffaloes. The IGF-2 concentration in Anatolian water buffaloes milk was 40.1 & PLUSMN;8.5 ng/ml. Milk IGF-2 was positively correlated with milk yield (r2=0.941, P<0.01). Our results showed that milk IGF-2 concentration was associated with milk yield in Anatolian buffaloes. These findings show that locally synthesized IGF-2 can affect milk yield. This study contributes to the understanding of the composition of buffalo milk, which has an important value in human nutrition. It is recommended to confirm the results of similar measurements in milk from other animal species used for human consumption.