Decreased Serum Adenosine Deaminase Activity Correlated with Clinical Score and Serum Proteins in Calves with Cryptosporidiosis
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Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Zoological Soc Pakistan
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
This study was aimed to investigate serum adenosine deaminase (ADA) activity in calves with cryptosporidiosis. Significantly higher serum concentrations of globulin (P<0.01), blood urea nitrogen (P<0.01) and creatinine (P<0.01) were found and significantly lower albumin concentration (P<0.01) and albumin to globulin (A/G) ratio (P<0.001) in calves with cryptosporidiosis compared to healthy calves. Serum adenosine deaminase (ADA) activity was determined as 4.12+/-0.91 U/l; in calves with cryptosporidiosis compared to 10.27+/-1.71 U/l in healthy calves, which was significant at P<0.01 level. Serum ADA was negatively correlated with clinical score (P<0.05), which serum total protein concentration (P<0.05), serum globulin concentration (P<0.01) and serum A/G ratio (P<0.05) were positivity correlated in calves with cryptosporidiosis. From these results we concluded that cryptosporidiosis infection is closely related to low serum ADA activity which correlated with clinical score and serum total protein, globulin and A/G ratio in-calves. The results of the present study indicate possible role of ADA in development and progression of cryptosporidiosis.
Açıklama
Anahtar Kelimeler
Adenosine deaminase, calf, cryptosporidiosis
Kaynak
Pakistan Journal Of Zoology
WoS Q Değeri
Q4
Scopus Q Değeri
Q4
Cilt
48
Sayı
4
Künye
closedAccess
