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Öğe Sanguisorba minor subsp. Balearica inhibit production of cytokines in a chronic model of inflammation induced by complete Freund's adjuvant(Elsevier Ireland Ltd, 2019) Genc, A. I.; Adali, O.; Kul, O.; Ozkan, A. M. GenclerRheumatoid arthritis is an idiopathic auto-immune disease characterized destruction of cartilage and synovial membrane. TNF-alpha, IL-12 and IL-1 are well known inflammatory mediators of “rheumatoid arthritis”. These cytokines activate synoviocytes and chondrocytes and this results in the secretion of matrix metalloproteinase into the synovial fluid. Analgesic and anti-inflammatory drugs are used to suppress the symptoms. However, all these have several side effects. New therapies targeting the underlying immune process have been proposed. Recent research aims to discover long-acting anti-inflammatory drugs with minimal side effects. Sanguisorba minor subsp. Balearica (Smb) is known as a medicinal plant and has been used for treatment of various disorders. The usage of Smb for relieving of inflammation is noteworthy. This study aims to invastigate possible cytokine mediated anti-inflammatory effects of (Smb) on arthritic ratsÖğe The Effects of Urotensin II Agonist and Antagonist on the Testicular Damage of Streptozotocin-induced Diabetic Rats(Wiley-Blackwell, 2016) Sengul, Emin; Gelen, Volkan; Celebi, Fikret; Cinar, Ali; Atmaca, Hasan Tarik…Öğe Effect Of Angiotensin Iı Receptor Blocker Telmisartan On Bone Fracture Healing In Rats: Relationship Between Vegf And Telmisartan(Springer London Ltd, 2015) Akoz, A.; Halici, Z.; Akpinar, E.; Topcu, A.; Yayla, M.; Aydin, A. Ali; Bayraktutan, Z.…Öğe Does Bosentan Protect Diabetic Brain Alterations in Rats? The Role of Endothelin-1 in the Diabetic Brain (conferenceObject)(Springer, 2015) Demir, R.; Cadirci, E.; Akpinar, E.; Cayir, Y.; Atmaca, H. T.; Un, H.; Demir…Öğe The effects of ozone therapy on cavernosal damage due to ischemia / reperfusion injury induced priapism in rat models(Wiley-Blackwell, 2011) Basar, M.; Aydos, T.; Kul, O.; Atmaca, T.; Uzunalioglu, T.; Kisa, U.…