Single, pauci, and multi-allergen immunotherapy

dc.contributor.authorCingi, C.
dc.contributor.authorWise, S. K.
dc.contributor.authorLin, S. Y.
dc.contributor.authorMuluk, N. Bayar
dc.contributor.authorFranzeses, C. B.
dc.contributor.authorRudenko, M.
dc.contributor.authorScadding, G. K.
dc.date.accessioned2020-06-25T18:29:59Z
dc.date.available2020-06-25T18:29:59Z
dc.date.issued2018
dc.departmentKırıkkale Üniversitesi
dc.description.abstractSingle, pauci, and multi-allergen immunotherapy. Objectives: This paper's aim is to review single, pauci, and multi-allergen immunotherapy. Methods: Search is made through PubMed, Google, Google Scholar and Proquest Central database of the Kirikkale University Library. Results: Allergen immunotherapy (AIT) modifies the immune response to a specific allergen. AIT has been used to treat allergic rhinitis, allergic conjunctivitis, allergic asthma and also insect venom allergy. Immunotherapy can be administered subcutaneously (SCIT) or sublingually (SLIT). Patients may be mono-, pauci-, or polysensitized to allergens. Polysensitization is more common and usually increases with age. AIT is maximally effective when one or two allergens are used. There is a similar effect in both mono and polysensitized patients. However, in polysensitized patients, immunotherapy with multiple allergens is less effective compared with desensitization treatment in monosensitized patients using one allergen. This may relate to dose, or to the fact that polysensitization might merely reflect cross-reactivity to one or two major causative allergens. Conclusion: We suggest that in polyallergy, where symptoms of rhinitis or asthma, are related to the exposure of multiple allergens; would be a better subject for multiple allergen desensitizations than polysensitization. This need is to explore in well-designed experiments.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.endpage84en_US
dc.identifier.issn1781-782X
dc.identifier.issue2en_US
dc.identifier.startpage79en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12587/7526
dc.identifier.volume14en_US
dc.identifier.wosWOS:000438319400001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherRoyal Belgian Soc Ear, Nose, Throat, Head & Neck Surgeryen_US
dc.relation.ispartofB-Ent
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAllergen immunotherapyen_US
dc.subjectallergensen_US
dc.subjectsensitizationen_US
dc.subjectsubcutaneous immunotherapyen_US
dc.subjectsublingual im-munotherapyen_US
dc.subjectallergic rhinitisen_US
dc.subjectallergic conjunctivitisen_US
dc.subjectallergic asthmaen_US
dc.subjectpolyallergyen_US
dc.subjectpolysensitizationen_US
dc.titleSingle, pauci, and multi-allergen immunotherapyen_US
dc.typeArticle

Dosyalar