Bacteriophage Applications to Control Listeria monocytogenes in Foods
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Tarih
2022
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Nova Science Publishers, Inc.
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Foods are playing a significant role in human infections and intoxications because they are frequent vehicles of some human pathogens. Animals are primary reservoir of many zoonotic diseases and can transmit pathogens via foods particularly with cross contamination during production and processing entire food chain. Due to lack of hygienic precautions during stable to table, contaminations of food and food products with Listeria monocytogenes can cause foodborne listeriosis. Bacteriophages were first described as bacteria-eating viruses. Compared to other antibacterial agents such as antibiotics and antiseptics, bacteriophages have a different and functional antimicrobial activity. Bacteriophages can be applied to living tissues without causing any harm due to their highly selective toxicity. This is the most important advantage when they compared with antibiotics and antiseptics. Rapidly growing bacterial resistance to antibiotics and urgent need for development of alternative methods, increasing interest in using bacteriophages in treatment, and prophylaxes or as biocontrol agents in foods nowadays. In addition to the systems like HACCP and GMP for food safety from farm to table, the use of specific virulent bacteriophages for Listeria monocytogenes in order to reduce the bacterial load in foods of animal origin emerges as promising method. It is reported that the use of specific virulent bacteriophages to Listeria monocytogenes as a biocontrol and decontamination agent in foods, don’t cause any side effects in humans. Although there are many advantages of bacteriophages such as specificity, effectiveness and showing no toxicity to humans, they have some disadvantages that limit their usage as a decontamination agent. Therefore, further studies should focus on improving the efficiency of lytic activity of bacteriophages to increase the reduction level of pathogens in different food models. Being not cost effective and easy to isolate from different sources make bacteriophages appropriate to be used in various forms such as mixing in food, spraying, attaching to food packaging material or dipping food in phage water alone and/or together with other inhibitors. The phages can prolong the shelf life of foods significantly. In addition to these, they can also be used for the decontamination of the surfaces of food processing plants, treatment of wastewater, and also phage therapy in human and animal diseases including listeriosis, since the world is entering most likely to a post antibiotic era because of rapid increase in antibiotic resistance of pathogens due to imprudent use of antimicrobials. © 2022 by Nova Science Publishers, Inc.
Açıklama
Anahtar Kelimeler
Bacteriophages; Biocontrol; Food; Listeria monocytogenes
Kaynak
Listeria Monocytogenes: Microbiology, Sites of Infection and Treatment
WoS Q Değeri
Scopus Q Değeri
N/A
