The Effective Ethanol Rate Against the Toxicity of Ethylene Glycol

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dc.contributor.authorGökalp, Faik
dc.date.accessioned2025-01-21T16:28:42Z
dc.date.available2025-01-21T16:28:42Z
dc.date.issued2021
dc.departmentKırıkkale Üniversitesi
dc.description.abstractEthylene glycol (EG) is a toxic substance and EG metabolites cause metabolic acidosis. The major emphasis in this study is to get rid of the toxicity of EG before conversion to its metabolites. The interaction between ethylene glycol and ethanol has been studied using DFT (Density functional theory method). In ethylene glycol metabolites in the blood; Glycolic acid is more stable and gloxal less stable. The interaction of ethylene glycol with ethanol has been considered for ethylene glycol metabolism. Thermodynamic values obtained from ethylene glycol metabolites and ethanol were also analyzed. According to the analyst results of ethanol and ethylene glycol ratios; The maximum effective point is very stable in the blood and its solubility is determined at this rate. It is very important to determine the most appropriate rate in the prevention of toxicity. This study is an important study in terms of the use of ethanol in the prevention of toxicity of EG, the first of its rates and in terms of preventing the loss of time and substance. © 2021. All Rights Reserved.
dc.description.sponsorshipKırıkkale University, (BAP-2016/016,2017/019)
dc.identifier.doi10.33435/TCANDTC.813939
dc.identifier.endpage26
dc.identifier.issn2587-1722
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85111260407
dc.identifier.scopusqualityQ3
dc.identifier.startpage20
dc.identifier.urihttps://doi.org/10.33435/TCANDTC.813939
dc.identifier.urihttps://hdl.handle.net/20.500.12587/23617
dc.identifier.volume5
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherDergiPark
dc.relation.ispartofTurkish Computational and Theoretical Chemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectblood; density functional theory; Ethanol; ethylene glycol; glyoxal
dc.titleThe Effective Ethanol Rate Against the Toxicity of Ethylene Glycol
dc.typeArticle

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