Evaluation of minimal erythema dose in patients who use dihydropyridinic calcium channel blockers

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dc.contributor.authorDemırkan, Serkan
dc.contributor.authorSavk, Ekin
dc.contributor.authorSendur, Neslihan
dc.contributor.authorKaraman, Goksun
dc.contributor.authorUslu, Meltem
dc.date.accessioned2025-01-21T16:17:23Z
dc.date.available2025-01-21T16:17:23Z
dc.date.issued2018
dc.departmentKırıkkale Üniversitesi
dc.description.abstractAim: One of the most frequent and reliable methods for determining phototoxicity is to monitor the minimal erythemadose(MED) related to UVA after using the drug.In our study, it was aimed to determine whether dihydropyridine-derived calcium channel blockers cause phototoxicity.Material and Methods: Eight open areas of 1 cm2 were left on the backs of the patients. Eight different doses of UVA wereapplied to these 8 areas starting at 2 j / cm2 and increasing to 16 j / cm2; After 24 hours, the first area which had significanterythema was checked. This value is defined as minimal erythematous dose (MED). MED values of patients were measuredbefore treatment and on the 7th day of treatment.Results: Thirty-nine hypertensive patients, 20 female and 19 male, were included in the study.Conclusion: Dihydropyridine-derived calcium channel blockers did not cause a change in MED for UVA and therefore didnot cause phototoxicity.
dc.identifier.doi10.18663/tjcl.370070
dc.identifier.endpage280
dc.identifier.issn2149-8296
dc.identifier.issue4
dc.identifier.startpage277
dc.identifier.trdizinid415045
dc.identifier.urihttps://doi.org/10.18663/tjcl.370070
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/415045
dc.identifier.urihttps://hdl.handle.net/20.500.12587/22627
dc.identifier.volume9
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofTurkish Journal of Clinics and Laboratory
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectGenel ve Dahili Tıp
dc.subjectTıbbi Laboratuar Teknolojisi
dc.titleEvaluation of minimal erythema dose in patients who use dihydropyridinic calcium channel blockers
dc.typeArticle

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