Investigation of the prognostic value of blood parameters in patients with rinoserebral mucormycosis

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dc.contributor.authorDemir, Ismail
dc.contributor.authorYalçın, Muhammed Zeki
dc.contributor.authorAydın, Sukru
dc.contributor.authorMuluk, Nuray Bayar
dc.contributor.authorBurulday, Veysel
dc.date.accessioned2025-01-21T16:13:20Z
dc.date.available2025-01-21T16:13:20Z
dc.date.issued2023
dc.departmentKırıkkale Üniversitesi
dc.description.abstractMucormycosis is a rapidly invasive, life-threatening opportunistic fungal infection, usually in immunocompromised patients. Suspicion, early diagnosis, debridement and anti-fungal treatment are important prognostic factors. The most common clinical manifestations of rhinocerebral mucormycosis are fever, headache, facial and ocular oedema. Invasion of surrounding tissues, the eye, skull base and brain is critical for disease progression. The purpose of this study was to investigate the predictive value of blood parameters in patients with mucormycosis. The preoperative 10-day blood parameters of 23 patients with clinical, radiological and pathological diagnoses of mucormycosis were compared in terms of etiology, gender and site of involvement. When the results were compared, the neutrophil-lymphocyte ratio (NLR) on days 1, 2, 5, 7, 8, 9, and 10 was significantly higher in patients with skull base involvement compared to those without skull base involvement (p<0.05). When comparing the regions of involvement, a significant correlation was found between cranial and turbinate involvement and between lamina papricea and ocular involvement (p<0.05). It was suggested that the NLR rate could be predicted as a poor prognostic factor in patients with mucormycosis.
dc.identifier.doi10.5455/medscience.2023.06.095
dc.identifier.endpage640
dc.identifier.issn2147-0634
dc.identifier.issue3
dc.identifier.startpage635
dc.identifier.trdizinid1259411
dc.identifier.urihttps://doi.org/10.5455/medscience.2023.06.095
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1259411
dc.identifier.urihttps://hdl.handle.net/20.500.12587/21901
dc.identifier.volume12
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofMedicine Science
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectTıbbi Araştırmalar Deneysel
dc.subjectGenel ve Dahili Tıp
dc.subjectPatoloji
dc.subjectMikrobiyoloji
dc.subjectKulak
dc.subjectBurun
dc.subjectBoğaz
dc.subjectSağlık Bilimleri ve Hizmetleri
dc.titleInvestigation of the prognostic value of blood parameters in patients with rinoserebral mucormycosis
dc.typeArticle

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