Bağ dokusu hastalıklarında koroidal kalınlık değişikleri
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Tarih
2016
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Çalışmanın amacı bağ dokusu hastalıklarında (BDH) koroid kalınlığı (KK) değişikliklerinin Spektral Domein optik koherens tomografi (SD OKT) kullanılarak değerlendirilmesidir.Gereç ve Yöntemler: Bu prospektif klinik çalışmada, en az 3 aydır remisyonda olan ve bağ dokusu hastalığı tanısı almış 34 hasta ve yaş ve cinsiyet uyumu olan 30 sağlam kişi kontrol grubu olarak değerlendirilmiştir. Santral makula kalınlığı (SMK) subfoveal, nazal ve temporal 500, 1500 mikron mesafelerdeki KK, SD OKT ile ölçülmüştür.Bulgular: Hasta grubunda ortalama SMK (219,2 ?m) kontrol grubuna göre (225,5 ?m) daha ince bulunmuştur. Ancak aradaki fark istatistiksel olarak anlamlı değildi (P = 0,2). Aynı zamanda ortalama KK her ölçüm noktası için hasta grubunda incelmiş olarak bulunmuştur fakat aradaki fark yine istatistiksel olarak anlamlı değildi (P > 0,05). Sonuçlar: İstatistiksel olarak anlamlı olmamasına rağmen BDH'larında koroid dokusu kalınlığı incelmiş olarak bulunmuştur
Aim: The aim of this study is to evaluate the choroidal thickness (CT) changes in connective tissue disease (CTD) using spectral domain optical coherence tomography (SD OCT) with enhanced depth imaging (EDI).Material and Methods: In this prospective clinical study, we included 34 subjects who were diagnosed as CTD in remission for at least 3 months, and age and gender matched 30 healthy controls. Central macular thickness (CMT), subfoveal CT, and CT at nasal (N) and temporal (T) distances of 500 ?m (N500 and T500, respectively) and 1500 ?m (N500 and T1500, respectively) from the central fovea were measured by EDI OCT.Results: The mean CMT of the patient group (219.2 ?m) was thinner compared to the control group (225.5 ?m), but the difference was not statistically significant (P = 0.2). At the same time, mean CT values were thinner at all measure points in the CTD subjects. The mean subfoveal CT, N500, N1500, T500 and T1500 were not significantly different in comparison to controls (all P > 0.05). Conclusion: Although our results did not reach statistical significance, we found that choroidal tissue was thinner in patients with CTD
Aim: The aim of this study is to evaluate the choroidal thickness (CT) changes in connective tissue disease (CTD) using spectral domain optical coherence tomography (SD OCT) with enhanced depth imaging (EDI).Material and Methods: In this prospective clinical study, we included 34 subjects who were diagnosed as CTD in remission for at least 3 months, and age and gender matched 30 healthy controls. Central macular thickness (CMT), subfoveal CT, and CT at nasal (N) and temporal (T) distances of 500 ?m (N500 and T500, respectively) and 1500 ?m (N500 and T1500, respectively) from the central fovea were measured by EDI OCT.Results: The mean CMT of the patient group (219.2 ?m) was thinner compared to the control group (225.5 ?m), but the difference was not statistically significant (P = 0.2). At the same time, mean CT values were thinner at all measure points in the CTD subjects. The mean subfoveal CT, N500, N1500, T500 and T1500 were not significantly different in comparison to controls (all P > 0.05). Conclusion: Although our results did not reach statistical significance, we found that choroidal tissue was thinner in patients with CTD
Açıklama
Anahtar Kelimeler
Tıbbi Laboratuar Teknolojisi, Tıbbi Araştırmalar Deneysel
Kaynak
Turkish Journal of Clinics and Laboratory
WoS Q Değeri
Scopus Q Değeri
Cilt
7
Sayı
3
Künye
Diner O., Ayyıldız Ö., Durukan H., Özge G., Küçükevcilioğlu M., Yumuşa E. (2016). Bağ dokusu hastalıklarında koroidal kalınlık değişikleri. Turkish Journal of Clinics and Laboratory, 7(3), 60 - 64.
