The Effect of Fluoride Toxication on Duodenum, Jejunum and Ileum of Broilers

Basit Öğe Kaydı
dc.contributor.authorAydoğan, İlkay
dc.contributor.authorYıldırım, Ebru
dc.contributor.authorKabakçı, Ruhi
dc.contributor.authorSümer, Tuğçe
dc.date.accessioned2025-01-21T16:19:36Z
dc.date.available2025-01-21T16:19:36Z
dc.date.issued2018
dc.departmentKırıkkale Üniversitesi
dc.description.abstractThe aim of this study is to evaluate the effect of fluoride toxication on the contraction and histopathological changes of duodenum, jejunum and ileum of broiler chicken. A total of 80 Ross 308 one-day-old male chicks assigned to 2 treatment groups with 4 replicates of 10 birds per replicated. 1st group was control group and the second group was a fluoride toxicated group, which was given 800 mg / kg flouride with the diet. Between 42 and 49 days of the study, randomly 3 chickens were chosen from each replicate group. Therefore totally 24 chickens were used to determine the contractile activity and examine the histopathological changes in the intestine. The broilers were decapitated and the duodenum, jejunum and ileum preparations were isolated, and mounted under 1 g of basal tension at isolated organ bath. The acetylcholine contractions were examined. There were no significant difference in the contraction of jejunum and ileum preparations, but the duodenum contractions were significantly decreased in fluoride given group as compared to control group, and in fluoride given group 7 of 13 duodenal samples showed no response to ACh. Microscopically; duodenal villus height / villus width ratio was 3.88 in fluoride group, while 6.84 in the control group. This significant ratio difference showed that fluoride could have a toxic effect caused by the villi thickness with severe mononuclear cell infiltration, hyperplasia of the lymphoid follicles and mild haemorrhagia in lamina propria. However there were no histopathological changes in jejunum and ileum between fluoride and control groups. These histopathological results were supported by the pharmacological findings. It is concluded that fluoride toxication affected the duodenal contractions and caused histopathological changes on the normal villus structure of duodenum in the broiler chicken.
dc.identifier.endpage39
dc.identifier.issn1302-3209
dc.identifier.issn2147-9003
dc.identifier.issue2
dc.identifier.startpage34
dc.identifier.trdizinid399234
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/399234
dc.identifier.urihttps://hdl.handle.net/20.500.12587/23121
dc.identifier.volume15
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofTavukçuluk Araştırma Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectZiraat Mühendisliği
dc.subjectGıda Bilimi ve Teknolojisi
dc.subjectVeterinerlik
dc.titleThe Effect of Fluoride Toxication on Duodenum, Jejunum and Ileum of Broilers
dc.typeArticle

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